Bases Moleculares de la Proliferación Celular y Enfermedades Raras

Lineas de Investigación

01. Angiogénesis y microentorno tumoral: Identificación y caracterización de moduladores de angiogénesis. Metabolismo en el microentorno tumoral.

02. Metabolismo de aminas biógenas y poliaminas en la salud y la enfermedad.

03. Bioinformática y redes: Modelos de interactomas, redes de enfermedad y de fármacos con métodos predictivos.

04. Flujos de trabajo bioinformáticos para la automatizacion de análisis genómicos. Análisis de expresión de transposones en cáncer.

05. Aplicaciones de las líneas 1-4 a las enfermedades raras.



Proyectos de Investigación

Medina Torres, Miguel Ángel

IP Acciones Complementarias

PLAN PROPIO_AREA 5_2020 Área 5. IBIMA Rare: Enfermedades raras

Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
. 2020

PID2019-108096RB-C21 Aproximaciones sistémicas basadas en asociaciones fenotipo-genotipo para mejorar el diagnóstico de pacientes con enfermedades raras

Ministerio de Asuntos Económicos y Transformación Digital
. 2020

PID2019-105010RB-I00. ANGIOGENESIS, INFLAMACION Y METABOLISMO COMO DIANAS TERAPEUTICAS DE LA ANGIOGENESIS PATOLOGICA EMPLEANDO ENFOQUES BIOTECNOLOGICOS

Ministerio de Asuntos Económicos y Transformación Digital
. 2020

PI-0075-2017 Utilización de Datos Clínicos E In Vitro para Desarrollar Un Modelo Predictivo de la Alergenicidad de Proteínas Vegetales de la Familia Ltp Mediante Métodos Bioinformáticos de Aprendizaje Autómatico.

CONSEJERÍA DE SALUD
PROYECTOS DE INVESTIGACIÓN EN SALUD 2017

Publicaciones científicas

  • Todo
  • D1
  • Q1
  • Q2
  • Otro


A comparative study of the antiangiogenic activity of hydroxytyrosyl alkyl ethers

Marrero AD, Castilla L, Espartero JL, Madrona A, R Quesada A, Medina MÁ, Martínez-Poveda B
Food Chem 2020 Dec 15;333:127476


Control of tumor angiogenesis and metastasis through modulation of cell redox state

Serrano JJ, Delgado B, Medina MÁ
Biochim Biophys Acta Rev Cancer 2020 Apr;1873(2):188352


An improved de novo assembling and polishing of Solea senegalensis transcriptome shed light on retinoic acid signalling in larvae

Córdoba-Caballero J, Seoane P, Jabato FM, Perkins JR, Manchado M, Claros MG
Sci Rep 2020 Nov 26;10(1):20654


Development of whole-genome multiplex assays and construction of an integrated genetic map using SSR markers in Senegalese sole

Guerrero-Cózar I, Perez-Garcia C, Benzekri H, Sánchez JJ, Seoane P, Cruz F, Gut M, Zamorano MJ, Claros MG, Manchado M
Sci Rep 2020 Dec 14;10(1):21905


Fasentin diminishes endothelial cell proliferation, differentiation and invasion in a glucose metabolism-independent manner

Ocaña MC, Martínez-Poveda B, Marí-Beffa M, Quesada AR, Medina MÁ
Sci Rep 2020 Apr 9;10(1):6132


Glucose Favors Lipid Anabolic Metabolism in the Invasive Breast Cancer Cell Line MDA-MB-231

Ocaña MC, Martínez-Poveda B, Quesada AR, Medina MÁ
Biology (Basel) 2020 Jan 10;9(1):16


In vitro evaluation of the antitumoral and antiangiogenic effects of extracts from Spondias mombin L

Rey-Blanes C, Pérez-Portero Y, Morris-Quevedo HJ, Casas V, Abdala R, Quesada AR, Martínez-Poveda B, Medina MÁ
leaves Biomed Pharmacother


Metabolic Reprogramming is a Hallmark of Metabolism Itself

Medina MÁ
Bioessays 2020 Oct;42(10):e2000058


Phenotype-genotype comorbidity analysis of patients with rare disorders provides insight into their pathological and molecular bases

Díaz-Santiago E, Jabato FM, Rojano E, Seoane P, Pazos F, Perkins JR, Ranea JAG
PLoS Genet 2020 Oct 1;16(10):e1009054


Gene Expression Profile of Mexican Lime (Citrus aurantifolia) Trees in Response to Huanglongbing Disease caused by Candidatus Liberibacter asiaticus

Arce-Leal ÁP, Bautista R, Rodríguez-Negrete EA, Manzanilla-Ramírez MÁ, Velázquez-Monreal JJ, Santos-Cervantes ME, Méndez-Lozano J, Beuzón CR, Bejarano ER, Castillo AG, Claros MG, Leyva-López NE
Microorganisms 2020 Apr 7;8(4):528


Graphene Oxide and Reduced Derivatives, as Powder or Film Scaffolds, Differentially Promote Dopaminergic Neuron Differentiation and Survival

Rodriguez-Losada N, Wendelbob R, Ocaña MC, Casares AD, Guzman de Villoría R, Aguirre Gomez JA, Arraez MA, Gonzalez-Alegre P, Medina MA, Arenas E, Narvaez JA
Front Neurosci 2020 Dec 21;14:570409


Expression-based, consistent biomarkers for prognosis and diagnosis in lung cancer

Arroyo M, Larrosa R, Gómez-Maldonado J, Cobo MÁ, Claros MG, Bautista R
Clin Transl Oncol 2020 Oct;22(10):1867-1874

  1. Ashford, P, Pang, CSM, Moya-García, AA, Adeyelu, T, Orengo, CA. A CATH domain functional family based approach to identify putative cancer driver genes and driver mutations. Sci Rep. 2019;9 (1):263. doi: 10.1038/s41598-018-36401-4. PubMed PMID:30670742 PubMed Central PMC6343001.
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  1. Arroyo, M, Bautista, R, Larrosa, R, Cobo, MÁ, Claros, MG. Biomarker potential of repetitive-element transcriptome in lung cancer. PeerJ. 2019;7 :e8277. doi: 10.7717/peerj.8277. PubMed PMID:31875158 PubMed Central PMC6925957.
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  1. Doña, I, Jurado-Escobar, R, Perkins, JR, Ayuso, P, Plaza-Serón, MC, Pérez-Sánchez, N et al.. Eicosanoid mediator profiles in different phenotypes of nonsteroidal anti-inflammatory drug-induced urticaria. Allergy. 2019;74 (6):1135-1144. doi: 10.1111/all.13725. PubMed PMID:30667070 .
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  1. Carrillo, P, Martínez-Poveda, B, Cheng-Sánchez, I, Guerra, J, Tobia, C, López-Romero, JM et al.. Exploring the Antiangiogenic Potential of Solomonamide A Bioactive Precursors: In Vitro and in Vivo Evidences of the Inhibitory Activity of Solo F-OH During Angiogenesis. Mar Drugs. 2019;17 (4):. doi: 10.3390/md17040228. PubMed PMID:30991727 PubMed Central PMC6520732.
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  1. Rodriguez, MJ, Ramos-Soriano, J, Perkins, JR, Mascaraque, A, Torres, MJ, Gomez, F et al.. Glycosylated nanostructures in sublingual immunotherapy induce long-lasting tolerance in LTP allergy mouse model. Sci Rep. 2019;9 (1):4043. doi: 10.1038/s41598-019-40114-7. PubMed PMID:30858392 PubMed Central PMC6411722.
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  1. Ocaña, MC, Martínez-Poveda, B, Quesada, AR, Medina, MÁ. Highly Glycolytic Immortalized Human Dermal Microvascular Endothelial Cells are Able to Grow in Glucose-Starved Conditions. Biomolecules. 2019;9 (8):. doi: 10.3390/biom9080332. PubMed PMID:31374952 PubMed Central PMC6723428.
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  1. Abdala Díaz, RT, Casas Arrojo, V, Arrojo Agudo, MA, Cárdenas, C, Dobretsov, S, Figueroa, FL et al.. Immunomodulatory and Antioxidant Activities of Sulfated Polysaccharides from Laminaria ochroleuca, Porphyra umbilicalis, and Gelidium corneum. Mar Biotechnol (NY). 2019;21 (4):577-587. doi: 10.1007/s10126-019-09905-x. PubMed PMID:31250232 .
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  1. Ocaña, MC, Martínez-Poveda, B, Quesada, AR, Medina, MÁ. Metabolism within the tumor microenvironment and its implication on cancer progression: An ongoing therapeutic target. Med Res Rev. 2019;39 (1):70-113. doi: 10.1002/med.21511. PubMed PMID:29785785 .
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  1. González-Gordo, S, Bautista, R, Claros, MG, Cañas, A, Palma, JM, Corpas, FJ et al.. Nitric oxide-dependent regulation of sweet pepper fruit ripening. J Exp Bot. 2019;70 (17):4557-4570. doi: 10.1093/jxb/erz136. PubMed PMID:31046097 PubMed Central PMC6736391.
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  1. García-Ponce, ÁL, Martínez-Poveda, B, Blanco-López, Á, Medina, MÁ, Quesada, AR. Not all has been said about glucose oxidase/peroxidase: New pedagogical uses for a classical and robust undergraduate laboratory experiment. Biochem Mol Biol Educ. 2019;47 (3):341-347. doi: 10.1002/bmb.21224. PubMed PMID:30735292 .
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  1. Sánchez-Jiménez, F, Medina, MÁ, Villalobos-Rueda, L, Urdiales, JL. Polyamines in mammalian pathophysiology. Cell Mol Life Sci. 2019;76 (20):3987-4008. doi: 10.1007/s00018-019-03196-0. PubMed PMID:31227845 .
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  1. Perkins, JR, Acosta-Herrera, M, Plaza-Serón, MC, Jurado-Escobar, R, Doña, I, García-Martín, E et al.. Polymorphisms in CEP68 gene associated with risk of immediate selective reactions to non-steroidal anti-inflammatory drugs. Pharmacogenomics J. 2019;19 (2):191-199. doi: 10.1038/s41397-018-0038-0. PubMed PMID:30093714 .
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  1. Palomares, F, Ramos-Soriano, J, Gomez, F, Mascaraque, A, Bogas, G, Perkins, JR et al.. Pru p 3-Glycodendropeptides Based on Mannoses Promote Changes in the Immunological Properties of Dendritic and T-Cells from LTP-Allergic Patients. Mol Nutr Food Res. 2019;63 (20):e1900553. doi: 10.1002/mnfr.201900553. PubMed PMID:31368251 .
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  1. Polonio, Á, Pineda, M, Bautista, R, Martínez-Cruz, J, Pérez-Bueno, ML, Barón, M et al.. RNA-seq analysis and fluorescence imaging of melon powdery mildew disease reveal an orchestrated reprogramming of host physiology. Sci Rep. 2019;9 (1):7978. doi: 10.1038/s41598-019-44443-5. PubMed PMID:31138852 PubMed Central PMC6538759.
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  1. Cheng-Sánchez, I, Torres-Vargas, JA, Martínez-Poveda, B, Guerrero-Vásquez, GA, Medina, MÁ, Sarabia, F et al.. Synthesis and Antitumor Activity Evaluation of Compounds Based on Toluquinol. Mar Drugs. 2019;17 (9):. doi: 10.3390/md17090492. PubMed PMID:31450731 PubMed Central PMC6780176.
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  1. Seoane, P, Tapia-Paniagua, ST, Bautista, R, Alcaide, E, Esteve, C, Martínez-Manzanares, E et al.. TarSynFlow, a workflow for bacterial genome comparisons that revealed genes putatively involved in the probiotic character of Shewanella putrefaciens strain Pdp11. PeerJ. 2019;7 :e6526. doi: 10.7717/peerj.6526. PubMed PMID:30842906 PubMed Central PMC6397758.
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  1. Polonio, Á, Seoane, P, Claros, MG, Pérez-García, A. The haustorial transcriptome of the cucurbit pathogen Podosphaera xanthii reveals new insights into the biotrophy and pathogenesis of powdery mildew fungi. BMC Genomics. 2019;20 (1):543. doi: 10.1186/s12864-019-5938-0. PubMed PMID:31272366 PubMed Central PMC6611051.
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  1. Martínez-Poveda, B, Torres-Vargas, JA, Ocaña, MDC, García-Caballero, M, Medina, MÁ, Quesada, AR et al.. The Mediterranean Diet, a Rich Source of Angiopreventive Compounds in Cancer. Nutrients. 2019;11 (9):. doi: 10.3390/nu11092036. PubMed PMID:31480406 PubMed Central PMC6769787.
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  1. Carrillo, P, Martínez-Poveda, B, Medina, MÁ, Quesada, AR. The strigolactone analog GR-24 inhibits angiogenesis in vivo and in vitro by a mechanism involving cytoskeletal reorganization and VEGFR2 signalling. Biochem Pharmacol. 2019;168 :366-383. doi: 10.1016/j.bcp.2019.07.019. PubMed PMID:31351052 .
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  1. Rodriguez, MJ, Palomares, F, Bogas, G, Torres, MJ, Diaz-Perales, A, Rojo, J et al.. Transcriptional Profiling of Dendritic Cells in a Mouse Model of Food-Antigen-Induced Anaphylaxis Reveals the Upregulation of Multiple Immune-Related Pathways. Mol Nutr Food Res. 2019;63 (3):e1800759. doi: 10.1002/mnfr.201800759. PubMed PMID:30458065 .
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  1. Carmona, R, Claros, M, de Alché, J. Bioinformatic Prediction of S-Nitrosylation Sites in Large Protein Datasets. Methods Mol Biol. 2018;1747 :241-250. doi: 10.1007/978-1-4939-7695-9_19. PubMed PMID:29600464 .
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  1. López-Jiménez, A, Gallardo, E, Espartero, JL, Madrona, A, Quesada, AR, Medina, MÁ et al.. Comparison of the anti-angiogenic potential of hydroxytyrosol and five derivatives. Food Funct. 2018;9 (8):4310-4316. doi: 10.1039/c8fo01140k. PubMed PMID:30040093 .
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  1. Romero-Sánchez, LB, Marí-Beffa, M, Carrillo, P, Medina, MÁ, Díaz-Cuenca, A. Copper-containing mesoporous bioactive glass promotes angiogenesis in an in vivo zebrafish model. Acta Biomater. 2018;68 :272-285. doi: 10.1016/j.actbio.2017.12.032. PubMed PMID:29288822 .
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  1. Cheng-Sánchez, I, Carrillo, P, Sánchez-Ruiz, A, Martínez-Poveda, B, Quesada, AR, Medina, MA et al.. Exploring the Ring-Closing Metathesis for the Construction of the Solomonamide Macrocyclic Core: Identification of Bioactive Precursors. J Org Chem. 2018;83 (10):5365-5383. doi: 10.1021/acs.joc.7b02988. PubMed PMID:29676156 .
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  1. García-Caballero, M, Quesada, AR, Medina, MA, Marí-Beffa, M. Fishing anti(lymph)angiogenic drugs with zebrafish. Drug Discov Today. 2018;23 (2):366-374. doi: 10.1016/j.drudis.2017.10.018. PubMed PMID:29081356 .
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  1. García-Vilas, JA, Morilla, I, Bueno, A, Martínez-Poveda, B, Medina, MÁ, Ranea, JAG et al.. In silico prediction of targets for anti-angiogenesis and their in vitro evaluation confirm the involvement of SOD3 in angiogenesis. Oncotarget. 2018;9 (25):17349-17367. doi: 10.18632/oncotarget.24693. PubMed PMID:29707113 PubMed Central PMC5915121.
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  1. Medina, MÁ. Mathematical modeling of cancer metabolism. Crit Rev Oncol Hematol. 2018;124 :37-40. doi: 10.1016/j.critrevonc.2018.02.004. PubMed PMID:29548484 .
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  1. Bueno, A, Rodríguez-López, R, Reyes-Palomares, A, Rojano, E, Corpas, M, Nevado, J et al.. Phenotype-loci associations in networks of patients with rare disorders: application to assist in the diagnosis of novel clinical cases. Eur J Hum Genet. 2018;26 (10):1451-1461. doi: 10.1038/s41431-018-0139-x. PubMed PMID:29946186 PubMed Central PMC6138686.
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  1. Herrera-Uribe, J, Zaldívar-López, S, Aguilar, C, Luque, C, Bautista, R, Carvajal, A et al.. Regulatory role of microRNA in mesenteric lymph nodes after Salmonella Typhimurium infection. Vet Res. 2018;49 (1):9. doi: 10.1186/s13567-018-0506-1. PubMed PMID:29391047 PubMed Central PMC5796392.
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  1. Mehta, PK, Jeon, J, Ryu, K, Park, SH, Lee, KH. Ratiometric fluorescent detection of lead ions in aquatic environment and living cells using a fluorescent peptide-based probe. J Hazard Mater. 2021;427 :128161. doi: 10.1016/j.jhazmat.2021.128161. PubMed PMID:35033727 .
  2. Alghamdi, AG, El-Saeid, MH, Alzahrani, AJ, Ibrahim, HM. Heavy metal pollution and associated health risk assessment of urban dust in Riyadh, Saudi Arabia. PLoS One. 2022;17 (1):e0261957. doi: 10.1371/journal.pone.0261957. PubMed PMID:34990460 PubMed Central PMC8735667.
  3. Bennett, G, Van Reybrouck, J, Shemsanga, C, Kisaka, M, Tomašek, I, Fontijn, K et al.. Identification of low fluoride areas using conceptual groundwater flow model and hydrogeochemical system analysis in the aquifer system on the flanks of an active volcano: Mount Meru, Northern Tanzania. Sci Total Environ. 2021;814 :152682. doi: 10.1016/j.scitotenv.2021.152682. PubMed PMID:34971682 .
  4. Cummings, JL, Atri, A, Ismail, Z, Dickerson, BC, Ballard, C, Grossberg, GT et al.. Development and assessment of a brief screening tool for psychosis in dementia. Alzheimers Dement. 2021;17 Suppl 8 :e057766. doi: 10.1002/alz.057766. PubMed PMID:34971295 .
  5. Yang, H, Sun, Z, Qin, X, Wu, H, Zhang, H, Liu, G et al.. Ultrasmall Au nanoparticles modified 2D metalloporphyrinic metal-organic framework nanosheets with high peroxidase-like activity for colorimetric detection of organophosphorus pesticides. Food Chem. 2021;376 :131906. doi: 10.1016/j.foodchem.2021.131906. PubMed PMID:34968912 .
  6. Zerizghi, T, Guo, Q, Tian, L, Wei, R, Zhao, C. An integrated approach to quantify ecological and human health risks of soil heavy metal contamination around coal mining area. Sci Total Environ. 2021;814 :152653. doi: 10.1016/j.scitotenv.2021.152653. PubMed PMID:34954188 .
  7. Huang, J, Wu, Y, Li, Y, Sun, J, Xie, Y, Fan, Z et al.. Do trace metal(loid)s in road soils pose health risks to tourists? A case of a highly-visited national park in China. J Environ Sci (China). 2022;111 :61-74. doi: 10.1016/j.jes.2021.02.032. PubMed PMID:34949374 .
  8. Kelekis, A, Bonaldi, G, Cianfoni, A, Filippiadis, D, Scarone, P, Bernucci, C et al.. Intradiscal oxygen-ozone chemonucleolysis versus microdiscectomy for lumbar disc herniation radiculopathy: a non-inferiority randomized control trial. Spine J. 2021; :. doi: 10.1016/j.spinee.2021.11.017. PubMed PMID:34896609 .
  9. Giazitzi, K, Ventat Oglou, B, Boskou, G. Do ready-to-eat meals of Greek supermarkets need reformulation?. Int J Food Sci Nutr. 2021; :1-10. doi: 10.1080/09637486.2021.2012645. PubMed PMID:34886768 .
  10. Krupnova, TG, Rakova, OV, Bondarenko, KA, Saifullin, AF, Popova, DA, Potgieter-Vermaak, S et al.. Elemental Composition of PM2.5 and PM10 and Health Risks Assessment in the Industrial Districts of Chelyabinsk, South Ural Region, Russia. Int J Environ Res Public Health. 2021;18 (23):. doi: 10.3390/ijerph182312354. PubMed PMID:34886089 PubMed Central PMC8657131.
  11. Li, Q, Li, G, Fan, L, Yu, Y, Liu, J. Click reaction triggered turn-on fluorescence strategy for highly sensitive and selective determination of steroid hormones in food samples. Food Chem. 2022;374 :131565. doi: 10.1016/j.foodchem.2021.131565. PubMed PMID:34875430 .
  12. Liu, Z, Duan, C, Liu, F, Chan, CCS, Zhu, H, Yuan, L et al.. Perovskite Bifunctional Diode with High Photovoltaic and Electroluminescent Performance by Holistic Defect Passivation. Small. 2021; :e2105196. doi: 10.1002/smll.202105196. PubMed PMID:34874619 .
  13. Cao, S, Wen, D, Chen, X, Duan, X, Zhang, L, Wang, B et al.. Source identification of pollution and health risks to metals in household indoor and outdoor dust: A cross-sectional study in a typical mining town, China. Environ Pollut. 2022;293 :118551. doi: 10.1016/j.envpol.2021.118551. PubMed PMID:34813887 .
  14. van Hemert, ND, Voskuil, M, Rozemeijer, R, Stein, M, Frambach, P, Pereira, B et al.. 3-Year Clinical Outcomes After Implantation of Permanent-Polymer Versus Polymer-Free Stent: ReCre8 Landmark Analysis. JACC Cardiovasc Interv. 2021;14 (22):2477-2486. doi: 10.1016/j.jcin.2021.08.078. PubMed PMID:34794654 .
  15. Huang, X, Sang, S, Yuan, Z, Duan, Q, Guo, X, Zhang, H et al.. Magnetoelastic Immunosensor via Antibody Immobilization for the Specific Detection of Lysozymes. ACS Sens. 2021;6 (11):3933-3939. doi: 10.1021/acssensors.1c00802. PubMed PMID:34677933 .
  16. Yoo, HJ, Li, YG, Cui, WY, Chung, W, Shin, YB, Kim, YS et al.. Discrimination and isolation of the virus from free RNA fragments for the highly sensitive measurement of SARS-CoV-2 abundance on surfaces using a graphene oxide nano surface. Nano Converg. 2021;8 (1):31. doi: 10.1186/s40580-021-00281-8. PubMed PMID:34661769 PubMed Central PMC8521082.
  17. Ko, E, Hur, W, Son, SE, Seong, GH, Han, DK. Au nanoparticle-hydrogel nanozyme-based colorimetric detection for on-site monitoring of mercury in river water. Mikrochim Acta. 2021;188 (11):382. doi: 10.1007/s00604-021-05032-4. PubMed PMID:34657212 .
  18. Hanfi, MY, Yarmoshenko, IV, Zhukovsky, MV. ASSESSMENT OF RADIATION DOSE FROM INHALATION OF OUTDOOR DUST CONTAINING NATURAL RADIONUCLIDES. Radiat Prot Dosimetry. 2021;196 (3-4):184-189. doi: 10.1093/rpd/ncab148. PubMed PMID:34608944 .
  19. Dehghani, M, Mohammadpour, A, Abbasi, A, Rostami, I, Gharehchahi, E, Derakhshan, Z et al.. Health risks of inhalation exposure to BTEX in a municipal wastewater treatment plant in Middle East city: Shiraz, Iran. Environ Res. 2022;204 (Pt B):112155. doi: 10.1016/j.envres.2021.112155. PubMed PMID:34606839 .
  20. Kong, H, Song, Z, Li, W, Bao, Y, Qu, D, Ma, Y et al.. Skin-Inspired Hair-Epidermis-Dermis Hierarchical Structures for Electronic Skin Sensors with High Sensitivity over a Wide Linear Range. ACS Nano. 2021;15 (10):16218-16227. doi: 10.1021/acsnano.1c05199. PubMed PMID:34605628 .
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  1. Seoane, P, Espigares, M, Carmona, R, Polonio, Á, Quintana, J, Cretazzo, E et al.. TransFlow: a modular framework for assembling and assessing accurate de novo transcriptomes in non-model organisms. BMC Bioinformatics. 2018;19 (Suppl 14):416. doi: 10.1186/s12859-018-2384-y. PubMed PMID:30453874 PubMed Central PMC6245506.
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  1. García-Vilas, JA, Medina, MÁ. Updates on the hepatocyte growth factor/c-Met axis in hepatocellular carcinoma and its therapeutic implications. World J Gastroenterol. 2018;24 (33):3695-3708. doi: 10.3748/wjg.v24.i33.3695. PubMed PMID:30197476 PubMed Central PMC6127652.
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  1. Fernández-Reina, A, Urdiales, JL, Sánchez-Jiménez, F. What We Know and What We Need to Know about Aromatic and Cationic Biogenic Amines in the Gastrointestinal Tract. Foods. 2018;7 (9):. doi: 10.3390/foods7090145. PubMed PMID:30181486 PubMed Central PMC6164962.
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  1. Carmona, R, Arroyo, M, Jiménez-Quesada, MJ, Seoane, P, Zafra, A, Larrosa, R et al.. Automated identification of reference genes based on RNA-seq data. Biomed Eng Online. 2017;16 (Suppl 1):65. doi: 10.1186/s12938-017-0356-5. PubMed PMID:28830520 PubMed Central PMC5568602.
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  1. Olsson, S, Seoane-Zonjic, P, Bautista, R, Claros, MG, González-Martínez, SC, Scotti, I et al.. Development of genomic tools in a widespread tropical tree, Symphonia globulifera L.f.: a new low-coverage draft genome, SNP and SSR markers. Mol Ecol Resour. 2017;17 (4):614-630. doi: 10.1111/1755-0998.12605. PubMed PMID:27718316 .
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  1. Jimenez-Quesada, MJ, Carmona, R, Lima-Cabello, E, Traverso, JÁ, Castro, AJ, Claros, MG et al.. Generation of nitric oxide by olive (Olea europaea L.) pollen during in vitro germination and assessment of the S-nitroso- and nitro-proteomes by computational predictive methods. Nitric Oxide. 2017;68 :23-37. doi: 10.1016/j.niox.2017.06.005. PubMed PMID:28645873 .
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  1. Balado, M, Benzekri, H, Labella, AM, Claros, MG, Manchado, M, Borrego, JJ et al.. Genomic analysis of the marine fish pathogen Photobacterium damselae subsp. piscicida: Insertion sequences proliferation is associated with chromosomal reorganisations and rampant gene decay. Infect Genet Evol. 2017;54 :221-229. doi: 10.1016/j.meegid.2017.07.007. PubMed PMID:28688976 .
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  1. Díaz-Santiago, E, Rodríguez-Caso, L, Cárdenas, C, Serrano, JJ, Quesada, AR, Medina, MÁ et al.. Homocysteine pre-treatment increases redox capacity in both endothelial and tumor cells. Redox Rep. 2017;22 (4):183-189. doi: 10.1080/13510002.2016.1183348. PubMed PMID:27198616 PubMed Central PMC6837415.
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  1. García-Vilas, JA, Quesada, AR, Medina, MÁ. Hydroxytyrosol targets extracellular matrix remodeling by endothelial cells and inhibits both ex vivo and in vivo angiogenesis. Food Chem. 2017;221 :1741-1746. doi: 10.1016/j.foodchem.2016.10.111. PubMed PMID:27979155 .
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  1. Zafra, A, Carmona, R, Traverso, JA, Hancock, JT, Goldman, MHS, Claros, MG et al.. Identification and Functional Annotation of Genes Differentially Expressed in the Reproductive Tissues of the Olive Tree (Olea europaea L.) through the Generation of Subtractive Libraries. Front Plant Sci. 2017;8 :1576. doi: 10.3389/fpls.2017.01576. PubMed PMID:28955364 PubMed Central PMC5601413.
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  1. Martínez-Poveda, B, Quesada, AR, Medina, MÁ. Pleiotropic Role of Puupehenones in Biomedical Research. Mar Drugs. 2017;15 (10):. doi: 10.3390/md15100325. PubMed PMID:29065486 PubMed Central PMC5666431.
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  1. García-Caballero, M, Martínez-Poveda, B, Medina, MA, Quesada, AR. The Natural Antiangiogenic Compound AD0157 Induces Caspase-Dependent Apoptosis in Human Myeloid Leukemia Cells. Front Pharmacol. 2017;8 :802. doi: 10.3389/fphar.2017.00802. PubMed PMID:29163182 PubMed Central PMC5682012.
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