Lineas de Investigación

01. Estudio de los mecanismos implicados en la generación del cáncer de piel con búsqueda específica de nuevos factores pronósticos, así como el abordaje terapeútico de las mismas.

02. Prevención del cáncer cutáneo con investigaciones en el campo de la fotoprotección

03. Análisis de la etiopatogenia de la psoriasis y su tratamiento tanto por mecanismos inmunoterapeúticos y fototerapia.



Estudios Clínicos

Ensayo Clínico fase II para evaluar la seguridad y eficacia de dos modelos de piel autóloga creada mediante ingeniería de tejidos en la cirugía reconstructiva del carcinoma basocelular..

Fundación Pública Andaluza Progreso y Salud
Fase: II Ensayo Clínico Comercial


Publicaciones científicas

  • Todo
  • D1
  • Q1
  • Q2
  • Otro

Long-term safety of nine systemic medications for psoriasis: A cohort study using the Spanish Registry of Adverse Events for Biological Therapy in Dermatological Diseases (BIOBADADERM) Registry

Daudén E, Carretero G, Rivera R, Ferrándiz C, Llamas-Velasco M, de la Cueva P, Belinchón I, Gómez-García FJ, Herrera-Acosta E, Ruiz-Genao DP, Ferrán-Farrés M, Alsina M, Baniandrés-Rodríguez O, Sánchez-Carazo JL, Sahuquillo-Torralba A, Fernández-Freire LR, Vilar-Alejo J, García-Donoso C, Carrascosa JM, Herrera-Ceballos E, López-Estebaranz JL, Botella-Estrada R, Segovia-Muñoz E, Descalzo MA, García-Doval I; BIOBADADERM Study Group
J Am Acad Dermatol 2020 Jul;83(1):139-150


Quality of Life of Cohabitants of People Living with Acne

Martínez-García E, Arias-Santiago S, Herrera-Acosta E, Affleck A, Herrera-Ceballos E, Buendía-Eisman A
Acta Derm Venereol 2020 Oct 14;100(17):adv00290


Skin and Arterial Wall Deposits of 18F-NaF and Severity of Disease in Patients with Pseudoxanthoma Elasticum

Gutierrez-Cardo A, Lillo E, Murcia-Casas B, Carrillo-Linares JL, García-Argüello F, Sánchez-Sánchez P, Rodriguez-Morata A, Aranda IB, Sánchez-Chaparro MÁ, García-Fernández M, Valdivielso P
J Clin Med 2020 May 8;9(5):1393


Comparative study of the efficacy and safety of secukinumab vs ixekizumab in moderate-to-severe psoriasis after 1 year of treatment: Real-world practice

Herrera-Acosta E, Garriga-Martina GG, Suárez-Pérez JA, Martínez-García EA, Herrera-Ceballos E
Dermatol Ther 2020 May;33(3):e13313


Effect of Nail Thickness on Visible Radiation Transmittance: Implications for New Photodynamic Therapy Technologies in Onychomycosis

de Gálvez EN, Aguilera J, de Gálvez MV, Fonda-Pascual P, Herrera-Ceballos E, Gago-Calderón A
Photochem Photobiol 2020 Nov;96(6):1267-1272


Ixekizumab vs ustekinumab for skin clearance in patients with moderate to severe psoriasis after a year of treatment: Real-world practice

Herrera-Acosta E, Garriga-Martina GG, Suárez-Pérez JA, Martínez-García E, Herrera-Ceballos E
Dermatol Ther 2020 Nov;33(6):e14202


Real-world effectiveness and safety of apremilast in psoriasis at 52 weeks: a retrospective, observational, multicentre study by the Spanish Psoriasis Group

Del Alcázar E, Suárez-Pérez JA, Armesto S, Rivera R, Herrera-Acosta E, Herranz P, Martín I, Montesinos E, Hospital M, Vilarrasa E, Ferran M, Ruiz-Villaverde R, Sahuquillo-Torralba A, Ruiz-Genao DP, Pérez-Barrio S, Muñoz C, Llamas M, Valentí F, Mitxelena MJ, López-Ferrer A, Carretero G, Vidal D, Mollet J, Belinchón I, Carrascosa JM
J Eur Acad Dermatol Venereol 2020 Dec;34(12):2821-2829

  1. Dirschka, T, Ekanayake-Bohlig, S, Dominicus, R, Aschoff, R, Herrera-Ceballos, E, Botella-Estrada, R et al.. A randomized, intraindividual, non-inferiority, Phase III study comparing daylight photodynamic therapy with BF-200 ALA gel and MAL cream for the treatment of actinic keratosis. J Eur Acad Dermatol Venereol. 2019;33 (2):288-297. doi: 10.1111/jdv.15185. PubMed PMID:30022544 PubMed Central PMC6585804.
Search PubMed
  1. Valencia-Vera, E, Aguilera, J, Cobos, A, Bernabó, JL, Pérez-Valero, V, Herrera-Ceballos, E et al.. Association between seasonal serum folate levels and ultraviolet radiation. J Photochem Photobiol B. 2019;190 :66-71. doi: 10.1016/j.jphotobiol.2018.10.012. PubMed PMID:30502586 .
Search PubMed
  1. Aterido, A, Cañete, JD, Tornero, J, Ferrándiz, C, Pinto, JA, Gratacós, J et al.. Genetic variation at the glycosaminoglycan metabolism pathway contributes to the risk of psoriatic arthritis but not psoriasis. Ann Rheum Dis. 2019;78 (3):. doi: 10.1136/annrheumdis-2018-214158. PubMed PMID:30552173 .
Search PubMed
  1. Montes-Torres, A, Aparicio, G, Rivera, R, Vilarrasa, E, Marcellán, M, Notario, J et al.. Safety and effectiveness of conventional systemic therapy and biological drugs in patients with moderate to severe psoriasis and HIV infection: a retrospective multicenter study. J Dermatolog Treat. 2019;30 (5):461-465. doi: 10.1080/09546634.2018.1535690. PubMed PMID:30307344 .
Search PubMed
  1. López Jiménez, P, Suárez Pérez, J, Herrera Acosta, E, Aguilera Arjona, J, Mendiola Fernández, MV, Bosch García, R et al.. Secukinumab versus ustekinumab for skin clearance in patients with moderate to severe psoriasis after a year of treatment: Real-world practice. Dermatol Ther. 2019;32 (4):e12937. doi: 10.1111/dth.12937. PubMed PMID:30983098 .
Search PubMed
  1. de la Coba, F, Aguilera, J, Korbee, N, de Gálvez, MV, Herrera-Ceballos, E, Álvarez-Gómez, F et al.. UVA and UVB Photoprotective Capabilities of Topical Formulations Containing Mycosporine-like Amino Acids (MAAs) through Different Biological Effective Protection Factors (BEPFs). Mar Drugs. 2019;17 (1):. doi: 10.3390/md17010055. PubMed PMID:30646557 PubMed Central PMC6356945.
Search PubMed
  1. de Gálvez, MV, Aguilera, J, Sánchez-Roldán, C, Herrera-Acosta, E, Herrera-Ceballos, E. Water-Filtered Infrared Radiation Decreases the Generation of Photodermatoses Dependent on Ultraviolet and Visible Radiation. Photochem Photobiol. 2019;95 (3):874-878. doi: 10.1111/php.13049. PubMed PMID:30447157 .
Search PubMed
  1. Baños-Arévalo, AJ, López-Navarro, N, Gallego-Domínguez, E, Herrera, E. Acral Metastasis of the Fingers: Report of 2 Cases. Actas Dermosifiliogr (Engl Ed). 2018;109 (10):e1-e4. doi: 10.1016/j.ad.2017.03.024. PubMed PMID:29724431 .
Search PubMed
  1. Garcia-Doval, I, Descalzo, MA, Mason, KJ, Cohen, AD, Ormerod, AD, Gómez-García, FJ et al.. Cumulative exposure to biological therapy and risk of cancer in patients with psoriasis: a meta-analysis of Psonet studies from Israel, Italy, Spain, the U.K. and Republic of Ireland. Br J Dermatol. 2018;179 (4):863-871. doi: 10.1111/bjd.16715. PubMed PMID:29723914 .
Search PubMed
  1. Cao, S, Wen, D, Chen, X, Duan, X, Zhang, L, Wang, B et al.. Source identification of pollution and health risks to metals in household indoor and outdoor dust: A cross-sectional study in a typical mining town, China. Environ Pollut. 2021;293 :118551. doi: 10.1016/j.envpol.2021.118551. PubMed PMID:34813887 .
  2. van Hemert, ND, Voskuil, M, Rozemeijer, R, Stein, M, Frambach, P, Pereira, B et al.. 3-Year Clinical Outcomes After Implantation of Permanent-Polymer Versus Polymer-Free Stent: ReCre8 Landmark Analysis. JACC Cardiovasc Interv. 2021;14 (22):2477-2486. doi: 10.1016/j.jcin.2021.08.078. PubMed PMID:34794654 .
  3. Huang, X, Sang, S, Yuan, Z, Duan, Q, Guo, X, Zhang, H et al.. Magnetoelastic Immunosensor via Antibody Immobilization for the Specific Detection of Lysozymes. ACS Sens. 2021;6 (11):3933-3939. doi: 10.1021/acssensors.1c00802. PubMed PMID:34677933 .
  4. Yoo, HJ, Li, YG, Cui, WY, Chung, W, Shin, YB, Kim, YS et al.. Discrimination and isolation of the virus from free RNA fragments for the highly sensitive measurement of SARS-CoV-2 abundance on surfaces using a graphene oxide nano surface. Nano Converg. 2021;8 (1):31. doi: 10.1186/s40580-021-00281-8. PubMed PMID:34661769 PubMed Central PMC8521082.
  5. Ko, E, Hur, W, Son, SE, Seong, GH, Han, DK. Au nanoparticle-hydrogel nanozyme-based colorimetric detection for on-site monitoring of mercury in river water. Mikrochim Acta. 2021;188 (11):382. doi: 10.1007/s00604-021-05032-4. PubMed PMID:34657212 .
  6. Hanfi, MY, Yarmoshenko, IV, Zhukovsky, MV. ASSESSMENT OF RADIATION DOSE FROM INHALATION OF OUTDOOR DUST CONTAINING NATURAL RADIONUCLIDES. Radiat Prot Dosimetry. 2021;196 (3-4):184-189. doi: 10.1093/rpd/ncab148. PubMed PMID:34608944 .
  7. Dehghani, M, Mohammadpour, A, Abbasi, A, Rostami, I, Gharehchahi, E, Derakhshan, Z et al.. Health risks of inhalation exposure to BTEX in a municipal wastewater treatment plant in Middle East city: Shiraz, Iran. Environ Res. 2021; :112155. doi: 10.1016/j.envres.2021.112155. PubMed PMID:34606839 .
  8. Kong, H, Song, Z, Li, W, Bao, Y, Qu, D, Ma, Y et al.. Skin-Inspired Hair-Epidermis-Dermis Hierarchical Structures for Electronic Skin Sensors with High Sensitivity over a Wide Linear Range. ACS Nano. 2021;15 (10):16218-16227. doi: 10.1021/acsnano.1c05199. PubMed PMID:34605628 .
  9. Ziembicki, S, Kirkham, TL, Demers, PA, Peters, CE, Gorman Ng, M, Davies, HW et al.. Diesel Engine Exhaust Exposure in the Ontario Civil Infrastructure Construction Industry. Ann Work Expo Health. 2021; :. doi: 10.1093/annweh/wxab068. PubMed PMID:34585719 .
  10. Zhu, L, Wei, Q, Porchas, M, Brierley, P, Friedman, M, Crosby, K et al.. Plant-based antimicrobials inactivate Listeria monocytogenes and Salmonella enterica on melons grown in different regions of the United States. Food Microbiol. 2022;101 :103876. doi: 10.1016/j.fm.2021.103876. PubMed PMID:34579844 .
  11. Lytou, AE, Schoina, E, Liu, Y, Michalek, K, Stanley, MS, Panagou, EZ et al.. Quality and Safety Assessment of Edible Seaweeds Alaria esculenta and Saccharina latissima Cultivated in Scotland. Foods. 2021;10 (9):. doi: 10.3390/foods10092210. PubMed PMID:34574321 PubMed Central PMC8472205.
  12. Zhang, W, Zhao, X, Diao, L, Li, H, Tong, Z, Gu, Z et al.. Highly Sensitive Uric Acid Detection Based on a Graphene Chemoresistor and Magnetic Beads. Biosensors (Basel). 2021;11 (9):. doi: 10.3390/bios11090304. PubMed PMID:34562894 PubMed Central PMC8468455.
  13. Li, J, Yang, Z, Mao, LF, Chen, RH, Yu, XF, Yang, XH et al.. Reverse transcription recombinase-aided amplification assay for rapid detection of the influenza A(H1N1)pdm09 H275Y mutation that confers oseltamivir resistance. Mol Cell Probes. 2021;60 :101771. doi: 10.1016/j.mcp.2021.101771. PubMed PMID:34560257 .
  14. Sankoh, A, Jin, W, Zhong, Z, He, J, Hong, Y, Giddings, R et al.. DFT-Spread Spectrally Overlapped Hybrid OFDM-Digital Filter Multiple Access IMDD PONs. Sensors (Basel). 2021;21 (17):. doi: 10.3390/s21175903. PubMed PMID:34502798 PubMed Central PMC8433889.
  15. Park, YJ, Woo, HY, Kim, MB, Ahn, J, Heo, J. Primary hepatic sarcoidosis presenting with cholestatic liver disease and mimicking primary biliary cholangitis. Yeungnam Univ J Med. 2021; :. doi: 10.12701/yujm.2021.01151. PubMed PMID:34411476 .
  16. Orellana Mendoza, E, Cuadrado, W, Yallico, L, Zárate, R, Quispe-Melgar, HR, Limaymanta, CH et al.. Heavy metals in soils and edible tissues of Lepidium meyenii (maca) and health risk assessment in areas influenced by mining activity in the Central region of Peru. Toxicol Rep. 2021;8 :1461-1470. doi: 10.1016/j.toxrep.2021.07.016. PubMed PMID:34401355 PubMed Central PMC8353470.
  17. Ma, X, Wu, J, Jiang, L, Wang, M, Deng, G, Qu, S et al.. On-chip integration of a metal-organic framework nanomaterial on a SiO2 waveguide for sensitive VOC sensing. Lab Chip. 2021;21 (17):3298-3306. doi: 10.1039/d1lc00503k. PubMed PMID:34378614 .
  18. Yang, M, Chen, Y, Yan, P, Dong, J, Duan, W, Xu, L et al.. A photoelectrochemical aptasensor of ciprofloxacin based on Bi24O31Cl10/BiOCl heterojunction. Mikrochim Acta. 2021;188 (9):289. doi: 10.1007/s00604-021-04952-5. PubMed PMID:34355248 .
  19. Willson-Kerns, C, Brazile, WJ. Noise Exposure and Evaluation at Tire- Changing Facilities. Ann Work Expo Health. 2021;65 (8):930-939. doi: 10.1093/annweh/wxab031. PubMed PMID:34228059 .
  20. Zou, Z, Shi, ZZ, Wu, JG, Wu, C, Zeng, QX, Zhang, YY et al.. Atomically Dispersed Co to an End-Adsorbing Molecule for Excellent Biomimetically and Prime Sensitively Detecting O2•- Released from Living Cells. Anal Chem. 2021;93 (31):10789-10797. doi: 10.1021/acs.analchem.1c00483. PubMed PMID:34212722 .
Search PubMed
  1. de Troya-Martín, M, de Gálvez-Aranda, MV, Rivas-Ruiz, F, Blázquez-Sánchez, N, Fernández-Morano, MT, Padilla-España, L et al.. Prevalence and predictors of sunburn among beachgoers. Photodermatol Photoimmunol Photomed. 2018;34 (2):122-129. doi: 10.1111/phpp.12354. PubMed PMID:28976044 .
Search PubMed
  1. Belinchón, I, Ramos, JM, Carretero, G, Ferrándiz, C, Rivera, R, Daudén, E et al.. Adverse events associated with discontinuation of the biologics/classic systemic treatments for moderate-to-severe plaque psoriasis: data from the Spanish Biologics Registry, Biobadaderm. J Eur Acad Dermatol Venereol. 2017;31 (10):1700-1708. doi: 10.1111/jdv.14314. PubMed PMID:28485816 .
Search PubMed
  1. Pérez-Plaza, A, Carretero, G, Ferrandiz, C, Vanaclocha, F, Gómez-García, FJ, Herrera-Ceballos, E et al.. Comparison of phenotype, comorbidities, therapy and adverse events between psoriatic patients with and without psoriatic arthritis. Biobadaderm registry. J Eur Acad Dermatol Venereol. 2017;31 (6):1021-1028. doi: 10.1111/jdv.14188. PubMed PMID:28252811 .
Search PubMed
  1. Dávila-Seijo, P, Dauden, E, Descalzo, MA, Carretero, G, Carrascosa, JM, Vanaclocha, F et al.. Infections in Moderate to Severe Psoriasis Patients Treated with Biological Drugs Compared to Classic Systemic Drugs: Findings from the BIOBADADERM Registry. J Invest Dermatol. 2017;137 (2):313-321. doi: 10.1016/j.jid.2016.08.034. PubMed PMID:27677836 .
Search PubMed
  1. Tejera-Vaquerizo, A, Pérez-Cabello, G, Marínez-Leborans, L, Gallego, E, Oliver-Martínez, V, Martín-Cuevas, P et al.. Is mitotic rate still useful in the management of patients with thin melanoma?. J Eur Acad Dermatol Venereol. 2017;31 (12):2025-2029. doi: 10.1111/jdv.14485. PubMed PMID:28750139 .
Search PubMed
  1. Losantos, R, Funes-Ardoiz, I, Aguilera, J, Herrera-Ceballos, E, García-Iriepa, C, Campos, PJ et al.. Rational Design and Synthesis of Efficient Sunscreens To Boost the Solar Protection Factor. Angew Chem Int Ed Engl. 2017;56 (10):2632-2635. doi: 10.1002/anie.201611627. PubMed PMID:28128519 .
Search PubMed
  1. Belinchón, I, Ramos, JM, Carretero, G, Ferrándiz, C, Rivera, R, Daudén, E et al.. Adverse events associated with discontinuation of the biologics/classic systemic treatments for moderate-to-severe plaque psoriasis: data from the Spanish Biologics Registry, Biobadaderm. J Eur Acad Dermatol Venereol. 2017;31 (10):1700-1708. doi: 10.1111/jdv.14314. PubMed PMID:28485816 .
Search PubMed
  1. Pérez-Plaza, A, Carretero, G, Ferrandiz, C, Vanaclocha, F, Gómez-García, FJ, Herrera-Ceballos, E et al.. Comparison of phenotype, comorbidities, therapy and adverse events between psoriatic patients with and without psoriatic arthritis. Biobadaderm registry. J Eur Acad Dermatol Venereol. 2017;31 (6):1021-1028. doi: 10.1111/jdv.14188. PubMed PMID:28252811 .
Search PubMed
  1. Dávila-Seijo, P, Dauden, E, Descalzo, MA, Carretero, G, Carrascosa, JM, Vanaclocha, F et al.. Infections in Moderate to Severe Psoriasis Patients Treated with Biological Drugs Compared to Classic Systemic Drugs: Findings from the BIOBADADERM Registry. J Invest Dermatol. 2017;137 (2):313-321. doi: 10.1016/j.jid.2016.08.034. PubMed PMID:27677836 .
Search PubMed
  1. Tejera-Vaquerizo, A, Pérez-Cabello, G, Marínez-Leborans, L, Gallego, E, Oliver-Martínez, V, Martín-Cuevas, P et al.. Is mitotic rate still useful in the management of patients with thin melanoma?. J Eur Acad Dermatol Venereol. 2017;31 (12):2025-2029. doi: 10.1111/jdv.14485. PubMed PMID:28750139 .
Search PubMed
  1. Losantos, R, Funes-Ardoiz, I, Aguilera, J, Herrera-Ceballos, E, García-Iriepa, C, Campos, PJ et al.. Rational Design and Synthesis of Efficient Sunscreens To Boost the Solar Protection Factor. Angew Chem Int Ed Engl. 2017;56 (10):2632-2635. doi: 10.1002/anie.201611627. PubMed PMID:28128519 .
Search PubMed
  1. de Troya-Martín, M, Padilla-España, L, Férnandez-Morano, T, Delgado-Sánchez, N, Blázquez Sánchez, N, Rivas-Ruiz, F et al.. Sun Protection Habits and Attitudes Among Healthcare Personnel in a Mediterranean Population. J Cancer Educ. 2016;31 (4):789-795. doi: 10.1007/s13187-015-0913-1. PubMed PMID:26370806 .
Search PubMed
  1. Dávila-Seijo, P, Dauden, E, Carretero, G, Ferrandiz, C, Vanaclocha, F, Gómez-García, FJ et al.. Survival of classic and biological systemic drugs in psoriasis: results of the BIOBADADERM registry and critical analysis. J Eur Acad Dermatol Venereol. 2016;30 (11):1942-1950. doi: 10.1111/jdv.13682. PubMed PMID:27329511 .
Search PubMed
  1. Julià, A, Pinto, JA, Gratacós, J, Queiró, R, Ferrándiz, C, Fonseca, E et al.. A deletion at ADAMTS9-MAGI1 locus is associated with psoriatic arthritis risk. Ann Rheum Dis. 2015;74 (10):1875-81. doi: 10.1136/annrheumdis-2014-207190. PubMed PMID:25990289 .
Search PubMed
  1. Julià, A, Ferrándiz, C, Dauden, E, Fonseca, E, Fernández-López, E, Sanchez-Carazo, JL et al.. Association of the PDE3A-SLCO1C1 locus with the response to anti-TNF agents in psoriasis. Pharmacogenomics J. 2015;15 (4):322-5. doi: 10.1038/tpj.2014.71. PubMed PMID:25403996 .
Search PubMed
  1. Tejera-Vaquerizo, A, Arias-Santiago, S, Nagore, E, Martín-Cuevas, P, Orgaz-Molina, J, Traves, V et al.. Defining the dermoscopic characteristics of fast-growing cutaneous melanomas. Melanoma Res. 2015;25 (3):269-72. doi: 10.1097/CMR.0000000000000157. PubMed PMID:25919929 .
Search PubMed
  1. Tejera-Vaquerizo, A, Nagore, E, Puig, S, Robert, C, Saiag, P, Martín-Cuevas, P et al.. Effect of time to sentinel-node biopsy on the prognosis of cutaneous melanoma. Eur J Cancer. 2015;51 (13):1780-93. doi: 10.1016/j.ejca.2015.05.023. PubMed PMID:26072362 PubMed Central PMC4768477.
Search PubMed
  1. de Gálvez, MV, Aguilera, J, Bernabó, JL, Sánchez-Roldán, C, Herrera-Ceballos, E. Human Hair as a Natural Sun Protection Agent: A Quantitative Study. Photochem Photobiol. ;91 (4):966-70. doi: 10.1111/php.12433. PubMed PMID:25682789 .
Search PubMed
  1. Carretero, G, Ferrandiz, C, Dauden, E, Vanaclocha Sebastián, F, Gómez-García, FJ, Herrera-Ceballos, E et al.. Risk of adverse events in psoriasis patients receiving classic systemic drugs and biologics in a 5-year observational study of clinical practice: 2008-2013 results of the Biobadaderm registry. J Eur Acad Dermatol Venereol. 2015;29 (1):156-63. doi: 10.1111/jdv.12492. PubMed PMID:24684267 .
Search PubMed
  1. Medina, C, Carretero, G, Ferrandiz, C, Dauden, E, Vanaclocha, F, Gómez-García, FJ et al.. Safety of classic and biologic systemic therapies for the treatment of psoriasis in elderly: an observational study from national BIOBADADERM registry. J Eur Acad Dermatol Venereol. 2015;29 (5):858-64. doi: 10.1111/jdv.12688. PubMed PMID:25185962 .
Search PubMed

Subscribe

Suscríbete a nuestro Newsletter y recibe en tu correo todas las últimas novedades del Instituto.
Consulta el histórico de Newsletter:

Calle Doctor Miguel Díaz Recio , 28 Málaga 29010

(+34) 951 440 260
Fax: (+34) 951 440 263