Degeneration and Regeneration of the Central Nervous System

Lineas de Investigación

01. Experimental studies on possible stem cell therapies in the treatment of foetal-neonatal hydrocephalus.

02. Long-term microglia conditioning.



Proyectos de Investigación

Terapia celular combinada basada en el uso de células madre no embrionarias humanas para la recuperación de la pared ventricular dañada por hidrocefalia

Universidad de Málaga
. 2019

Evaluación de una innovadora terapia celular para el tratamiento de la hidrocefalia posthemorrágica basada en células madre mesenquimales e inducidas humanas

Junta de Andalucía
. 2019

PI19/00778 Testing non-embryonic based stem cells as regenerative cell sources for treating neonates with intraventricular hemorrhages that develop posthemorrhagic hydrocephalus. IP ANTONIO JESUS JIMENEZ LARA

ISCIII
. 2019

Publicaciones científicas

  • Todo
  • D1
  • Q1
  • Q2
  • Otro

Pharmacological blockade of fatty acid amide hydrolase (FAAH) by URB597 improves memory and changes the phenotype of hippocampal microglia despite ethanol exposure

Rivera, P; Fernandez-Arjona, MD; Silva-Pena, D; Blanco, E; Vargas, A; Lopez-Avalos, MD; Grondona, JM; Serrano, A; Pavon, FJ; de Fonseca, FR; Suarez, J
Biochemical Pharmacology 2018


Evaluation of the quality of care of elderly patients with chronic and breakthrough pain treated with opioids: SAND study

Rodriguez, MJ; de la Torre, R; Ortega, JL; Trinidad, JM; Benitez, D; Jimenez, AJ; Sanz-Yague, A; Soler, B; Torres, LM
Current Medical Research And Opinion 2018


Stress, Depression, Resilience and Ageing: A Role for the LPA-LPA(1) Pathway

Roman, MF; Sara, T; Estela, CO; Margarita, PM; Guillermo, ET; Fernando, RD; Javier, SL; Carmen, P
Current Neuropharmacology 2018


Effects of genetic deletion versus pharmacological blockade of the LPA(1) receptor on depression-like behaviour and related brain functional activity

Moreno-Fernandez, RD; Nieto-Quero, A; Gomez-Salas, FJ; Chun, J; Estivill-Torrus, G; de Fonseca, FR; Santin, LJ; Perez-Martin, M; Pedraza, C
Disease Models & Mechanisms 2018


A Simple Endoscopic Score Modified for the Upper Gastrointestinal Tract in Crohn’s Disease [UGI-SES-CD]: A Report From the ImageKids Study

Ledder, O; Church, P; Cytter-Kuint, R; Martinez-Leon, M; Sladek, M; Coppenrath, E; Weiss, B; Yerushalmi, B; de Carpi, JM; Duchano, L; Towbin, A; Assa, A; Shaoul, R; Mearin, ML; Alex, G; Griffiths, A; Tumer, D
Journal Of Crohns & Colitis 2018


A Distinct Metabolite Profile Correlates with Neurodegenerative Conditions and the Severity of Congenital Hydrocephalus.

Garcia-Bonilla, Maria; Garcia-Martin, Maria L; Munoz-Hernandez, M Carmen; Dominguez-Pinos, Dolores; Martinez-Leon, Maria I; Penalver, Ana; Castilla, Laura; Alonso, Francisco J; Marquez, Javier; Shumilov, Kirill; Hidalgo-Sanchez, Ramon; Gutierrez, Antonia; Paez-Gonzalez, Patricia; Jimenez, Antonio J
Journal Of Neuropathology And Experimental Neurology 2018


Expression of a Novel Ciliary Protein, IIIG9, During the Differentiation and Maturation of Ependymal Cells

Cifuentes, M; Baeza, V; Arrabal, PM; Visser, R; Grondona, JM; Saldivia, N; Martinez, F; Nualart, F; Salazar, K
Molecular Neurobiology 2018


SVCT2 Expression and Function in Reactive Astrocytes Is a Common Event in Different Brain Pathologies

Salazar, K; Martinez, F; Perez-Martin, M; Cifuentes, M; Trigueros, L; Ferrada, L; Espinoza, F; Saldivia, N; Bertinat, R; Forman, K; Oviedo, MJ; Lopez-Gambero, AJ; Bonansco, C; Bongarzone, ER; Nualart, F
Molecular Neurobiology 2018

maLPA1-null mice as an endophenotype of anxious depression

Moreno-Fernandez, RD; Perez-Martin, M; Castilla-Ortega, E; del Valle, CR; Garcia-Fernandez, MI; Chun, J; Estivill-Torrus, G; de Fonseca, FR; Santin, LJ; Pedraza, CTranslational Psychiatry. 2017

Microglia Morphological Categorization in a Rat Model of Neuroinflammation by Hierarchical Cluster and Principal Components Analysis

Fernandez-Arjona, MD; Grondona, JM; Granados-Duran, P; Fernandez-Llebrez, P; Lopez-Avalos, MDFrontiers In Cellular Neuroscience. 2017

Perianal Pediatric Crohn Disease Is Associated With a Distinct Phenotype and Greater Inflammatory Burden

Assa, A; Amitai, M; Greer, ML; Castro, DA; Kuint, RC; Martinez-Leon, M; Herman-Sucharska, I; Coppenrath, E; Anupindi, S; Towbin, A; Moote, D; Konen, O; Pratt, LT; Griffiths, A; Turner, DJournal Of Pediatric Gastroenterology And Nutrition. 2017

Ventricular Zone Disruption in Human Neonates With Intraventricular Hemorrhage

McAllister, JP; Guerra, MM; Ruiz, LC; Jimenez, AJ; Dominguez-Pinos, D; Sival, D; den Dunnen, W; Morales, DM; Schmidt, RE; Rodriguez, EM; Limbrick, DDJournal Of Neuropathology And Experimental Neurology. 2017

Microbial neuraminidase induces a Moderate and Transient Myelin Vacuolation independent of complement system activation

Granados-Duran, P; Lopez-Avalos, MD; Cifuentes, M; Perez-Martin, M; Fernandez-Arjona, MD; Hughes, TR; Johnson, K; Morgan, BP; Fernandez-Llebrez, P; Grondona, JMFrontiers In Neurology. 2017

A vesicle trafficking protein alpha SNAP regulates Paneth cell differentiation in vivo

Lechuga, S; Naydenov, NG; Feygin, A; Jimenez, AJ; Ivanov, AIBiochemical And Biophysical Research Communications. 2017


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