Lineas de Investigación

01. Estudio de las bases embrionarias de la enfermedad cardiovascular. Estudio de los mecanismos celulares y moleculares de la fisiopatología cardiovascular

02. Desarrollo embrionario cardiovascular.

03. Reparación y regeneración cardiovascular.

04. Fibrosis en el contexto de las cardiomiopatías.

05. Histopatología cardiovascular.

06. Diferenciación de progenitores cardiovasculares.

07. Patología vascular.



Proyectos de Investigación

PIER-0084-2019. Origen embrionario del Síndrome de Canal Auriculoventricular Completo-Tetralogía de Fallot (CAVC-ToF) y del Defecto de la Comunicación Interauricular (CIA): Mecanismos Celulares y Moleculares.

Consejería de Salud y Familias
. 2019

PC-0066-2017 Funciones del Gen Wt1 en el Miocardio Embrionario y Adulto de Un Modelo Animal

CONSEJERÍA DE SALUD
PROYECTOS DE INVESTIGACIÓN COORDINADOS 2017

RD16/0011/0030 Red de Terapia Celular – TerCel

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONVOCATORIA DE REDES TEMÁTICAS DE INVESTIGACIÓN COOPERATIVA EN SALUD (RETICS) 2016

Publicaciones científicas

  • Todo
  • D1
  • Q1
  • Q2
  • Otro
  1. Skröder, H, Pettersson, H, Norlén, F, Gustavsson, P, Rylander, L, Albin, M et al.. Occupational exposure to whole body vibrations and birth outcomes - A nationwide cohort study of Swedish women. Sci. Total Environ. 2020;751 :141476. doi: 10.1016/j.scitotenv.2020.141476. PubMed PMID:32871309 .
  2. Tudi, M, Ruan, HD, Yu, Y, Wang, L, Wei, B, Tong, S et al.. Bioaccumulation and translocation of trace elements in soil-irrigation water-wheat in arid agricultural areas of Xin Jiang, China. Ecotoxicology. 2020; :. doi: 10.1007/s10646-020-02267-4. PubMed PMID:32860622 .
  3. Kim, SJ, Oh, MJ. Potentiality to natural immunization inducement against VHS in olive flounder by live VHSV immersion vaccination at temperature controlled culture condition. Virus Res. 2020;288 :198140. doi: 10.1016/j.virusres.2020.198140. PubMed PMID:32846195 .
  4. Wallentine, S, Bandaranayake, S, Biswas, S, Baker, LR. Plasmon-Resonant Vibrational Sum Frequency Generation of Electrochemical Interfaces: Direct Observation of Carbon Dioxide Electroreduction on Gold. J Phys Chem A. 2020; :. doi: 10.1021/acs.jpca.0c04268. PubMed PMID:32846085 .
  5. Tirloni, E, Nauta, M, Vasconi, M, Di Pietro, V, Bernardi, C, Stella, S et al.. Growth of Listeria monocytogenes in ready-to-eat "shrimp cocktail": Risk assessment and possible preventive interventions. Int. J. Food Microbiol. 2020;334 :108800. doi: 10.1016/j.ijfoodmicro.2020.108800. PubMed PMID:32829187 .
  6. Dey Bhowmik, A, Podder, S, Mondal, P, Shaw, P, Bandyopadhyay, A, Das, A et al.. Chronic exposure to environmentally relevant concentration of fluoride alters Ogg1 and Rad51 expressions in mice: Involvement of epigenetic regulation. Ecotoxicol. Environ. Saf. 2020;202 :110962. doi: 10.1016/j.ecoenv.2020.110962. PubMed PMID:32800233 .
  7. Mahfooz, Y, Yasar, A, Guijian, L, Islam, QU, Akhtar, ABT, Rasheed, R et al.. Critical risk analysis of metals toxicity in wastewater irrigated soil and crops: a study of a semi-arid developing region. Sci Rep. 2020;10 (1):12845. doi: 10.1038/s41598-020-69815-0. PubMed PMID:32733057 PubMed Central PMC7393170.
  8. Han, L, Peng, R, Jiang, W, Xu, T, Zhang, C, Chen, K et al.. Coordination-driven reversible surfaces with site-specifically immobilized nanobody for dynamic cancer cell capture and release. J Mater Chem B. 2020;8 (33):7511-7520. doi: 10.1039/d0tb00574f. PubMed PMID:32677632 .
  9. Zhao, ML, Zeng, WJ, Chai, YQ, Yuan, R, Zhuo, Y. An Affinity-Enhanced DNA Intercalator with Intense ECL Embedded in DNA Hydrogel for Biosensing Applications. Anal. Chem. 2020;92 (16):11044-11052. doi: 10.1021/acs.analchem.0c00152. PubMed PMID:32677426 .
  10. Yu, H, McCuller, L, Tse, M, Kijbunchoo, N, Barsotti, L, Mavalvala, N et al.. Quantum correlations between light and the kilogram-mass mirrors of LIGO. Nature. 2020;583 (7814):43-47. doi: 10.1038/s41586-020-2420-8. PubMed PMID:32612226 .
  11. Souza Neto, HF, Pereira, WVDS, Dias, YN, Souza, ES, Teixeira, RA, Lima, MW et al.. Environmental and human health risks of arsenic in gold mining areas in the eastern Amazon. Environ. Pollut. 2020;265 (Pt B):114969. doi: 10.1016/j.envpol.2020.114969. PubMed PMID:32559696 .
  12. Ge, R, Zhao, H, Wei, JX, Duan, YQ, Bai, Z, Li, C et al.. Improved two-step optimization procedure used for designing an apodizer and Lyot stop in the Lyot coronagraph. Appl Opt. 2020;59 (16):4939-4952. doi: 10.1364/AO.391959. PubMed PMID:32543491 .
  13. Akshaya, KB, Anitha, V, Nidhin, M, Sudhakar, YN, Louis, G. Electrochemical sensing of vitamin B12 deficiency marker methylmalonic acid using PdAu-PPy tailored carbon fiber paper electrode. Talanta. 2020;217 :121028. doi: 10.1016/j.talanta.2020.121028. PubMed PMID:32498897 .
  14. Tamele, IJ, Vasconcelos, V. Microcystin Incidence in the Drinking Water of Mozambique: Challenges for Public Health Protection. Toxins (Basel). 2020;12 (6):. doi: 10.3390/toxins12060368. PubMed PMID:32498435 PubMed Central PMC7354522.
  15. Bandi, R, Alle, M, Park, CW, Han, SY, Kwon, GJ, Kim, JC et al.. Rapid synchronous synthesis of Ag nanoparticles and Ag nanoparticles/holocellulose nanofibrils: Hg(II) detection and dye discoloration. Carbohydr Polym. 2020;240 :116356. doi: 10.1016/j.carbpol.2020.116356. PubMed PMID:32475600 .
  16. Zhao, X, Yang, Y, Chiribella, G. Quantum Metrology with Indefinite Causal Order. Phys. Rev. Lett. 2020;124 (19):190503. doi: 10.1103/PhysRevLett.124.190503. PubMed PMID:32469602 .
  17. Ayres Cacciatore, F, Dalmás, M, Maders, C, Ataíde Isaía, H, Brandelli, A, da Silva Malheiros, P et al.. Carvacrol encapsulation into nanostructures: Characterization and antimicrobial activity against foodborne pathogens adhered to stainless steel. Food Res. Int. 2020;133 :109143. doi: 10.1016/j.foodres.2020.109143. PubMed PMID:32466924 .
  18. Wang, Y, Yu, J, Mao, YF, Chen, J, Wang, S, Chen, HZ et al.. Stable, high-performance sodium-based plasmonic devices in the near infrared. Nature. 2020;581 (7809):401-405. doi: 10.1038/s41586-020-2306-9. PubMed PMID:32461649 .
  19. Löfgren, L, Forsberg, GB, Davidsson, P, Eketjäll, S, Whatling, C. Development of a highly sensitive liquid chromatography-mass spectrometry method to quantify plasma leukotriene E4 and demonstrate pharmacological suppression of endogenous 5-LO pathway activity in man. Prostaglandins Other Lipid Mediat. 2020;150 :106463. doi: 10.1016/j.prostaglandins.2020.106463. PubMed PMID:32450304 .
  20. Bao, H, Duan, J, Jin, S, Lu, X, Li, P, Qu, W et al.. Spin squeezing of 1011 atoms by prediction and retrodiction measurements. Nature. 2020;581 (7807):159-163. doi: 10.1038/s41586-020-2243-7. PubMed PMID:32405021 .
Search PubMed
  1. Carmona, R, Ariza, L, Cano, E, Jiménez-Navarro, M, Muñoz-Chápuli, R. Mesothelial-mesenchymal transitions in embryogenesis. Semin. Cell Dev. Biol. 2019;92 :37-44. doi: 10.1016/j.semcdb.2018.09.006. PubMed PMID:30243860 .
Search PubMed
  1. Skröder, H, Pettersson, H, Norlén, F, Gustavsson, P, Rylander, L, Albin, M et al.. Occupational exposure to whole body vibrations and birth outcomes - A nationwide cohort study of Swedish women. Sci. Total Environ. 2020;751 :141476. doi: 10.1016/j.scitotenv.2020.141476. PubMed PMID:32871309 .
  2. Tudi, M, Ruan, HD, Yu, Y, Wang, L, Wei, B, Tong, S et al.. Bioaccumulation and translocation of trace elements in soil-irrigation water-wheat in arid agricultural areas of Xin Jiang, China. Ecotoxicology. 2020; :. doi: 10.1007/s10646-020-02267-4. PubMed PMID:32860622 .
  3. Kim, SJ, Oh, MJ. Potentiality to natural immunization inducement against VHS in olive flounder by live VHSV immersion vaccination at temperature controlled culture condition. Virus Res. 2020;288 :198140. doi: 10.1016/j.virusres.2020.198140. PubMed PMID:32846195 .
  4. Wallentine, S, Bandaranayake, S, Biswas, S, Baker, LR. Plasmon-Resonant Vibrational Sum Frequency Generation of Electrochemical Interfaces: Direct Observation of Carbon Dioxide Electroreduction on Gold. J Phys Chem A. 2020; :. doi: 10.1021/acs.jpca.0c04268. PubMed PMID:32846085 .
  5. Tirloni, E, Nauta, M, Vasconi, M, Di Pietro, V, Bernardi, C, Stella, S et al.. Growth of Listeria monocytogenes in ready-to-eat "shrimp cocktail": Risk assessment and possible preventive interventions. Int. J. Food Microbiol. 2020;334 :108800. doi: 10.1016/j.ijfoodmicro.2020.108800. PubMed PMID:32829187 .
  6. Dey Bhowmik, A, Podder, S, Mondal, P, Shaw, P, Bandyopadhyay, A, Das, A et al.. Chronic exposure to environmentally relevant concentration of fluoride alters Ogg1 and Rad51 expressions in mice: Involvement of epigenetic regulation. Ecotoxicol. Environ. Saf. 2020;202 :110962. doi: 10.1016/j.ecoenv.2020.110962. PubMed PMID:32800233 .
  7. Mahfooz, Y, Yasar, A, Guijian, L, Islam, QU, Akhtar, ABT, Rasheed, R et al.. Critical risk analysis of metals toxicity in wastewater irrigated soil and crops: a study of a semi-arid developing region. Sci Rep. 2020;10 (1):12845. doi: 10.1038/s41598-020-69815-0. PubMed PMID:32733057 PubMed Central PMC7393170.
  8. Han, L, Peng, R, Jiang, W, Xu, T, Zhang, C, Chen, K et al.. Coordination-driven reversible surfaces with site-specifically immobilized nanobody for dynamic cancer cell capture and release. J Mater Chem B. 2020;8 (33):7511-7520. doi: 10.1039/d0tb00574f. PubMed PMID:32677632 .
  9. Zhao, ML, Zeng, WJ, Chai, YQ, Yuan, R, Zhuo, Y. An Affinity-Enhanced DNA Intercalator with Intense ECL Embedded in DNA Hydrogel for Biosensing Applications. Anal. Chem. 2020;92 (16):11044-11052. doi: 10.1021/acs.analchem.0c00152. PubMed PMID:32677426 .
  10. Yu, H, McCuller, L, Tse, M, Kijbunchoo, N, Barsotti, L, Mavalvala, N et al.. Quantum correlations between light and the kilogram-mass mirrors of LIGO. Nature. 2020;583 (7814):43-47. doi: 10.1038/s41586-020-2420-8. PubMed PMID:32612226 .
  11. Souza Neto, HF, Pereira, WVDS, Dias, YN, Souza, ES, Teixeira, RA, Lima, MW et al.. Environmental and human health risks of arsenic in gold mining areas in the eastern Amazon. Environ. Pollut. 2020;265 (Pt B):114969. doi: 10.1016/j.envpol.2020.114969. PubMed PMID:32559696 .
  12. Ge, R, Zhao, H, Wei, JX, Duan, YQ, Bai, Z, Li, C et al.. Improved two-step optimization procedure used for designing an apodizer and Lyot stop in the Lyot coronagraph. Appl Opt. 2020;59 (16):4939-4952. doi: 10.1364/AO.391959. PubMed PMID:32543491 .
  13. Akshaya, KB, Anitha, V, Nidhin, M, Sudhakar, YN, Louis, G. Electrochemical sensing of vitamin B12 deficiency marker methylmalonic acid using PdAu-PPy tailored carbon fiber paper electrode. Talanta. 2020;217 :121028. doi: 10.1016/j.talanta.2020.121028. PubMed PMID:32498897 .
  14. Tamele, IJ, Vasconcelos, V. Microcystin Incidence in the Drinking Water of Mozambique: Challenges for Public Health Protection. Toxins (Basel). 2020;12 (6):. doi: 10.3390/toxins12060368. PubMed PMID:32498435 PubMed Central PMC7354522.
  15. Bandi, R, Alle, M, Park, CW, Han, SY, Kwon, GJ, Kim, JC et al.. Rapid synchronous synthesis of Ag nanoparticles and Ag nanoparticles/holocellulose nanofibrils: Hg(II) detection and dye discoloration. Carbohydr Polym. 2020;240 :116356. doi: 10.1016/j.carbpol.2020.116356. PubMed PMID:32475600 .
  16. Zhao, X, Yang, Y, Chiribella, G. Quantum Metrology with Indefinite Causal Order. Phys. Rev. Lett. 2020;124 (19):190503. doi: 10.1103/PhysRevLett.124.190503. PubMed PMID:32469602 .
  17. Ayres Cacciatore, F, Dalmás, M, Maders, C, Ataíde Isaía, H, Brandelli, A, da Silva Malheiros, P et al.. Carvacrol encapsulation into nanostructures: Characterization and antimicrobial activity against foodborne pathogens adhered to stainless steel. Food Res. Int. 2020;133 :109143. doi: 10.1016/j.foodres.2020.109143. PubMed PMID:32466924 .
  18. Wang, Y, Yu, J, Mao, YF, Chen, J, Wang, S, Chen, HZ et al.. Stable, high-performance sodium-based plasmonic devices in the near infrared. Nature. 2020;581 (7809):401-405. doi: 10.1038/s41586-020-2306-9. PubMed PMID:32461649 .
  19. Löfgren, L, Forsberg, GB, Davidsson, P, Eketjäll, S, Whatling, C. Development of a highly sensitive liquid chromatography-mass spectrometry method to quantify plasma leukotriene E4 and demonstrate pharmacological suppression of endogenous 5-LO pathway activity in man. Prostaglandins Other Lipid Mediat. 2020;150 :106463. doi: 10.1016/j.prostaglandins.2020.106463. PubMed PMID:32450304 .
  20. Bao, H, Duan, J, Jin, S, Lu, X, Li, P, Qu, W et al.. Spin squeezing of 1011 atoms by prediction and retrodiction measurements. Nature. 2020;581 (7807):159-163. doi: 10.1038/s41586-020-2243-7. PubMed PMID:32405021 .
Search PubMed
  1. Herrero, D, Cañón, S, Pelacho, B, Salvador-Bernáldez, M, Aguilar, S, Pogontke, C et al.. Bmi1-Progenitor Cell Ablation Impairs the Angiogenic Response to Myocardial Infarction. Arterioscler. Thromb. Vasc. Biol. 2018;38 (9):2160-2173. doi: 10.1161/ATVBAHA.118.310778. PubMed PMID:29930004 PubMed Central PMC6202133.
Search PubMed
  1. Ariza, L, Cañete, A, Rojas, A, Muñoz-Chápuli, R, Carmona, R. Role of the Wilms' tumor suppressor gene Wt1 in pancreatic development. Dev. Dyn. 2018;247 (7):924-933. doi: 10.1002/dvdy.24636. PubMed PMID:29708625 .
Search PubMed
  1. Cañete, A, Carmona, R, Ariza, L, Sánchez, MJ, Rojas, A, Muñoz-Chápuli, R et al.. A population of hematopoietic stem cells derives from GATA4-expressing progenitors located in the placenta and lateral mesoderm of mice. Haematologica. 2017;102 (4):647-655. doi: 10.3324/haematol.2016.155812. PubMed PMID:28057738 PubMed Central PMC5395105.
Search PubMed
  1. Carmona, R, Cañete, A, Cano, E, Ariza, L, Rojas, A, Muñoz-Chápuli, R et al.. Conditional deletion of WT1 in the septum transversum mesenchyme causes congenital diaphragmatic hernia in mice. Elife. 2016;5 :. doi: 10.7554/eLife.16009. PubMed PMID:27642710 PubMed Central PMC5028188.
Search PubMed
  1. Cano, E, Carmona, R, Ruiz-Villalba, A, Rojas, A, Chau, YY, Wagner, KD et al.. Extracardiac septum transversum/proepicardial endothelial cells pattern embryonic coronary arterio-venous connections. Proc. Natl. Acad. Sci. U.S.A. 2016;113 (3):656-61. doi: 10.1073/pnas.1509834113. PubMed PMID:26739565 PubMed Central PMC4725486.
Search PubMed
  1. Villa Del Campo, C, Lioux, G, Carmona, R, Sierra, R, Muñoz-Chápuli, R, Clavería, C et al.. Myc overexpression enhances of epicardial contribution to the developing heart and promotes extensive expansion of the cardiomyocyte population. Sci Rep. 2016;6 :35366. doi: 10.1038/srep35366. PubMed PMID:27752085 PubMed Central PMC5082763.
Search PubMed
  1. Ruiz-Villalba, A, Simón, AM, Pogontke, C, Castillo, MI, Abizanda, G, Pelacho, B et al.. Interacting resident epicardium-derived fibroblasts and recruited bone marrow cells form myocardial infarction scar. J. Am. Coll. Cardiol. 2015;65 (19):2057-66. doi: 10.1016/j.jacc.2015.03.520. PubMed PMID:25975467 .
Search PubMed
  1. Cano, E, Carmona, R, Velecela, V, Martínez-Estrada, O, Muñoz-Chápuli, R. The proepicardium keeps a potential for glomerular marker expression which supports its evolutionary origin from the pronephros. Evol. Dev. ;17 (4):224-30. doi: 10.1111/ede.12130. PubMed PMID:26174098 .
Search PubMed

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