Lineas de Investigación

Estudio de reacciones alérgicas

01. Reacciones de hipersensibilidad a fármacos mediadas por mecanismos inmunológicos específicos, IgE o células T.

02. Reacciones de hipersensibilidad a fármacos mediadas por otros mecanismos.

03. Reacciones alérgicas a alimentos.

04. Enfermedades alérgicas respiratorias: rinitis y asma

05. Tratamiento inmunomoduladores específicos: Inmunoterapia y desensibilización

Proyecto DIFAMEM



Proyectos de Investigación

RH-0085-2020_NPS Optimización del diagnóstico y tratamiento de las enfermedades alérgicas

Consejería de Salud y Familias
. 2020

EIR20-002 Premio Ibima-Eir al mejor expediente investigador

Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
. 2020

CPII20-00028 Contratos Miguel Servet Tipo IIl 2020 María Isabel Montañez Vega

Instituto de Salud Carlos III
. 2020

A1-0030-2020 Solicitud para el refuerzo anual de la actividad investigadora en las unidades asistenciales del servicio andaluz de Salud ( SAS)

Servicio Andaluz de Salud (SAS)
. 2020

SFC-0002-2020 Papel de las células linfoides innatas tipo 2 en las reacciones alérgicas a alimentos y evaluación de la de la respuesta inmunológica inducida por la inmunoterapia con alérgenos.

Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
. 2020

PI-0099-2020 Papel de las células linfoides innatas tipo 2 (ILC2) en las reacciones alérgicas a alimentos y su implicación en la respuesta inmunológica durante la inmunoterapia especifica.

Consejería de Salud y Familias
. 2020

PI20/01715 Estudio de la prevalencia, clarificación de la inmunopatología e identificaicón de biomarcadores diagnósticos de alergia respiratoria local en fenotipos graves y de díficil control de rinitis y asma

Instituto de Salud Carlos III
. 2020

PI20/01540 Hipersensibilidad a anti-inflamatorios no esteroides: Fenotipado preciso e historia natural. Papel de la atopía y de una respuesta inmute innata

Instituto de Salud Carlos III
. 2020

PI20/01540 Hipersensibilidad a anti-inflamatorios no esteroides: Fenotipado preciso e historia natural. Papel de la atopía y de una respuesta inmute innata

Consejería de Salud y Familias
. 2020

PI-0127-2020 Aproximación diagnóstica al paciente alérgico a antibióticos betalactámicos mediante la optimización del test de activación de basófilos profundizando en los mecanismos de degranulación del basófilo y la sensibilización pasiva.

Consejería de Salud y Familias
. 2020

RH-0099-2020_AAV Optimización del diagnóstico y tratamiento de las enfermedades alérgicas

Consejería de Salud y Familias
. 2020

PI20/01734 Nanoarquitecturas altamente eficientes para un entrecruzamiento eficaz de la IgE en mastocitos y basófilos. Aplicación al diagnóstico de reacciones alérgicas a amoxicilina y ácido clavulánico

Instituto de Salud Carlos III
. 2020

CA18226 – New approaches for the detection of pathogens and aeroallergens

Comisión Europea
. 2019

C1-0019-2019 SOLICITUD PARA EL PROGRAMA NICOLÁS MONARDES, CONVOCATORIA 2019

Servicio Andaluz de Salud (SAS)
. 2019

B-0005-2019 ACCIONES PARA EL REFUERZO CON RECURSOS HUMANOS DE LA ACTIVIDAD INVESTIGADORA EN LAS UNIDADES DE GESTIÓN CLÍNICA DEL SERVICIO ANDALUZ DE SALUD 2019. ACCIÓN B CLÍNICOS INVESTIGADORES.

Servicio Andaluz de Salud (SAS)
. 2019

A1-0015-2019 SOLICITUD PARA EL REFUERZO ANUAL DE LA ACTIVIDAD INVESTIGADORA EN LAS UNIDADES DE GESTIÓN CLÍNICA (UGC) DEL SERVICIO ANDALUZ DE SALUD (SAS)

Servicio Andaluz de Salud (SAS)
. 2019

PI-0076-2019. CARACTERIZACIÓN DEL FENOTIPO-ENDOTIPO E IDENTIFICACIÓN DE BIOMARCADORES EN REACCIONES DE HIPERSENSIBILIDAD A QUIMIOTERÁPICOS (SALES DE PLATINO Y TAXANOS)

Consejería de Salud y Familias
. 2019

AC19/00082 DrNanoDAll – Nanodiagnosis for Betalactam Hypersensitivity

ISCIII
. 2019

SEAIC 18B02. “Hipersensibilidad cruzada a ibuprofeno y otros derivados arilpropiónicos: entidades clínicas y mecanismos. Atopia e interacción fenotipo-genotipo”.

SOCIEDAD ESPAÑOLA DE ALERGOLOGÍA E INMUNOLOGÍA CLÍNICA
Sociedad Española de Alergología e Inmunología Clínica 2019

EF-0162-2018. Endofenotipos graves de enfermedades alérgicas respiratorias

CONSEJERÍA DE SALUD
ESTANCIAS FORMATIVAS DE INVESTIGACIÓN E INNOVACIÓN 2018

CM17/00141 Rio Hortega

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS RÍO HORTEGA 2017

MS15/00103 Contrato Miguel Servet Tipo I

INSTITUTO DE SALUD CARLOS III
CONTRATOS MIGUEL SERVET TIPO I 2015

PI17/01237 Aplicación de nanoarquitecturas sintéticas al estudio de los mecanismos de activación del basófilo y al diagnóstico en reacciones alérgicas a amoxicilina.

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD (FIS) 2017

CP15/00103 Development of antibiotic conjugates with nanostructures or proteins and their application to the in vitro diagnosis of antibiotic allergy

INSTITUTO DE SALUD CARLOS III
CONTRATOS MIGUEL SERVET TIPO I 2015

B-0001-2017_Acción B Clínicos investigadores

SERVICIO ANDALUZ DE SALUD
ACCIÓN B - CLÍNICOS INVESTIGADORES. REFUERZO ANUAL DE LA ACTIVIDAD INVESTIGADORA EN LAS UGC DEL SAS 2017

JR15/00036 Contrato Juan Rodés

INSTITUTO DE SALUD CARLOS III
CONTRATOS JUAN RODES 2015

SEAIC-002-2016 Hipersensibilidad a antiinflamatorios no esteroideos: caracterización de nuevos fenotipos, papel de la atopia y análisis de la historia natural

SOCIEDAD ESPAÑOLA DE ALERGOLOGÍA E INMUNOLOGÍA CLINICA
AYUDAS PARA TRABAJOS DE INVESTIGACIÓN SEAIC 2016

PI17/01593 Hipersensibilidad a anti-inflamatorios no esteroideos por intolerancia cruzada: definición precisa de fenotipos, historia natural y mecanismos implicados.

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD (FIS) 2017

RYC-2013-13138 Ramón y Cajal Tahía Diana Fernández Duarte. Se presenta por el área científica de Biomedicina

MINISTERIO DE ECONOMIA Y EMPRESA
AYUDAS RAMÓN Y CAJAL 2014

PI-0241-2016 Desarrollo de Métodos In Vitro para el Diagnóstico de Alergia Al Ácido Clavulánico: Identificación de Los Determinantes Antigénicos Implicados en la Respuesta Inmunológica

CONSEJERÍA DE SALUD
PROYECTOS DE INVESTIGACIÓN EN SALUD 2016

FI18-00133 Contrato PFIS 2018 Raquel Jurado Escobar. Jefe de Grupo: José Antonio Cornejo García

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS PFIS: CONTRATOS PREDOCTORALES DE FORMACIÓN EN INVESTIGACIÓN EN SALUD 2018

RB-0001-2018 Estudio de mecanismos inmunológicos y búsqueda de biomarcadores en hipersensibilidad a fármacos, alergia respiratoria y alergia a alimentos. UGC Alergología del HRUM

SERVICIO ANDALUZ DE SALUD
RENOVACIÓN DE LA ACCIÓN B (REFUERZOS DE LARGA DURACIÓN) DE LA CONVOCATORIA 2018

INT18/00006 AllerScreening. Point of care device based on KETs for diagnosis of food allergies

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS JOSÉ MARÍA SEGOVIA DE ARANA 2018

RD16/0006/0001 Asma, Reacciones Adversas y Alérgicas – ARADYAL

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONVOCATORIA DE REDES TEMÁTICAS DE INVESTIGACIÓN COOPERATIVA EN SALUD (RETICS) 2016

PE-0172-2018. Aplicación de nano-partículas y búsqueda de biomarcadores para el diagnóstico in vitro de alergia a betalactámicos.

CONSEJERÍA DE SALUD
PROYECTOS ESTRATÉGICOS DE I+D+i CON FORTALECIMIENTO DE CAPITAL HUMANO INVESTIGADOR 2018

PI18/00095 Aproximación diagnóstica al paciente alérgico a betalactámicos mediante modelos matemáticos y pruebas in vitro. Estrategia innovadora de tratamiento basada en nano-estructuras.

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD 2018

MV18-00014 Papel de las Células Linfoides Innatas de Tipo 2 (ILC2) en el desarrollo de tolerancia inmunológica durante la inmunoterapia específica con el alérgeno

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - MOVILIDAD DE PERSONAL INVESTIGADOR CONTRATADO EN EL MARCO DE LA AES (M-AES) 2018

CD16/00042 Contrato Sara Borrell 2016 Mª Francisca Palomares Jerez Jefe de Grupo: Cristobalina Mayorga Mayorga

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS SARA BORRELL 2016

PC-0098-2017 Estudio de la Respuesta Inmunológica Humoral y de Células Efectoras Clásicas en Pacientes Con Asma Alérgico Local

CONSEJERÍA DE SALUD
PROYECTOS DE INVESTIGACIÓN COORDINADOS 2017

MS14/00034 Contrato Miguel Servet Tipo I José Antonio Cornejo García

INSTITUTO DE SALUD CARLOS III
CONTRATOS MIGUEL SERVET TIPO I 2014

CM17/00140 Rio Hortega 2017 Ibon Eguiluz Gracia.Jefe de grupo: Cristobalina Mayorga Mayorga

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS RÍO HORTEGA 2017

PI-0176-2018. Identificación multidimensional de biomarcadores diagnósticos, pronósticos y de respuesta a corticoides en pacientes con enfermedad alérgica respiratoria

CONSEJERÍA DE SALUD
PROYECTOS DE INVESTIGACIÓN EN SALUD 2018

JR18-00054 Contrato Juan Rodés 2018 GADOR BOGAS HERRERA

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS JUAN RODÉS 2018

JR15/00034 Contrato Juan Rodes Francisca Gómez Pérez

INSTITUTO DE SALUD CARLOS III
CONTRATOS JUAN RODES 2015

PI17/01318 Identificación de biomarcadores de utilidad diagnóstica en pacientes con alergia a LTP de fenotipo grave. Mecanismos implicados en la eficacia de la inmunoterapia con LTP

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD (FIS) 2017

RC-0004-2016 Accion C Nicolas Monardes Cristobalina Mayorga

SERVICIO ANDALUZ DE SALUD
RENOVACIÓN ACCIÓN C (PROGRAMA NICOLÁS MONARDES) DE LA CONVOCATORIA 2016

PE-0039-2018. Intervención con prebióticos para el tratamiento de alergia a alimentos

CONSEJERÍA DE SALUD
PROYECTOS ESTRATÉGICOS DE I+D+i CON FORTALECIMIENTO DE CAPITAL HUMANO INVESTIGADOR 2018

PI18-00288 Biomarcadores inmunológicos y epigenéticos de tolerancia a alérgenos alimentarios inducida por inmunoterapia basada en nanoestructuras oligodendriméricas y epítopos T

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD 2018

PI17/01410 Estudio clínico e inmunológico de la vía aérea inferior y de la respuesta a la inmunoterapia con alérgeno en pacientes con rinitis alérgica local

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD (FIS) 2017

CD17/00146 Sara Borrell 2017 Adriana Ariza Veguillas.Jefe de Grupo Carmen Rondon Segovia

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS SARA BORRELL 2017

Estudios Clínicos

Ensayo prospectivo multicéntrico aleatorizado, controlado con placebo y comparativo de la eficacia y la seguridad de la inmunoterapia subcutánea con mezcla de gramíneas y ácaros a dosis adecuadas frente a monoterapia, para el tratamiento de la alergia.

INMUNOTEK, S.L.
Fase: III Ensayo Clínico Comercial

Estudio de fase II para evaluar la tolerabilidad, seguridad y eficacia de la inmunoterapia sublingual en pacientes con alergia a los ácaros del polvo doméstico..

ROXALL MEDICINA ESPAÑA, S.A.
Fase: II Ensayo Clínico Comercial

Estudio de extensión multicéntrico, doble ciego y abierto para evaluar la eficacia y seguridad de ligelizumab como retratamiento, terapia autoadministrada y monoterapia en pacientes con urticaria crónica espontánea que han completado los estudios CQGE031C.

NOVARTIS FARMACEUTICA, S.A.
Fase: III Ensayo Clínico Comercial

Estudio de fase 3, aleatorizado y en doble ciego, sobre la eficacia y la seguridad de ABP 938 en comparación con aflibercept (Eylea®) en sujetos con degeneración macular neovascular relacionada con la edad.

AMGEN INC.
Fase: III Ensayo Clínico Comercial

CQGE031C2302. Estudio multicéntrico, aleatorizado, doble ciego, con control activo y placebo para investigar la eficacia y seguridad de ligelizumab (QGE031) en el tratamiento de la urticaria crónica espontánea (UCE) en adolescentes y adultos inadecuadamente controlados

NOVARTIS FARMACEUTICA, S.A.
Fase: III ENSAYO CLINICO COMERCIAL

CQGE031C2201E1. Estudio de extensión, multicéntrico, abierto para evaluar la seguridad a largo plazo de QGE031 240 mg s.c. administrado cada 4 semanas durante 52 semanas en pacientes con urticaria espontánea crónica que hayan completado el estudio CQGE031C2201

NOVARTIS FARMACEUTICA, S.A.
Fase: II ENSAYO CLINICO COMERCIAL

AL1402ac. Estudio multicéntrico, aleatorio, doble ciego adaptativo, controlado con placebo para la evaluación de la eficacia y la seguridad de inmunoterapia especifica con una preparación alergoide de ácaros de polvo doméstico (Dermatophagoides Pteronyssinus) adher

ALLERGOPHARMA GMBH & CO. KG
Fase: III ENSAYO CLINICO COMERCIAL

AL-X-01. Seguridad y tolerabilidad de una pauta acortada de tratamiento con Alutard SQ

ALK-ABELLO A/S
Fase: II ENSAYO CLINICO COMERCIAL


Publicaciones científicas

  • Todo
  • D1
  • Q1
  • Q2
  • Otro
Allergies and COVID-19 vaccines: An ENDA/EAACI Position paper

Barbaud A, Garvey LH, Arcolaci A, Brockow K, Mori F, et al. Allergy 2022 Feb 2;():

Sequential class switch recombination to IgE and allergen-induced accumulation of IgE+ plasmablasts occur in the nasal mucosa of local allergic rhinitis patients.

Testera-Montes, Almudena; Palomares, Francisca; Jurado-Escobar, Raquel; Fernandez-Santamaria, Ruben; Ariza, Adriana; Verge, Jesus; Salas, Maria; Campo, Paloma; Mayorga, Cristobalina; Torres, Maria Jose; Rondon, Carmen; Eguiluz-Gracia, Ibon Allergy 2022

EAACI position paper on the clinical use of the bronchial allergen challenge: Unmet needs and research priorities

Agache I, Antolin-Amerigo D, de Blay F, Boccabella C, Caruso C, et al. Allergy 2022 Jun;77(6):1667-1684

Adalimumab in Elderly Patients with Non-Infectious Uveitis. Safety and Efficacy

Moll-Udina A, Miguel Escuder L, Hernanz I, Llorenç V, Fonollosa A, et al. Ocular immunology and inflammation 2021 Nov 17;29(7-8):1591-1598

Anaphylaxis and Pregnancy: A Systematic Review and Call for Public Health Actions

Carra S, Schatz M, Mertes PM, Torres MJ, Fuchs F, et al. The journal of allergy and clinical immunology. In practice 2021 Dec;9(12):4270-4278

ARADyAL: The Spanish Multidisciplinary Research Network for Allergic Diseases

Torres MJ, Agundez J, Barber D, Bartra J, Davila I, et al. Journal of investigational allergology & clinical immunology 2021 Apr 20;31(2):108-119

ARIA-EAACI care pathways for allergen immunotherapy in respiratory allergy

Bousquet J, Pfaar O, Agache I, Bedbrook A, Akdis CA, et al. Clinical and translational allergy 2021 Jun;11(4):e12014

ARIA-EAACI statement on severe allergic reactions to COVID-19 vaccines – An EAACI-ARIA Position Paper

Klimek L, Jutel M, Akdis CA, Bousquet J, Akdis M, et al. Allergy 2021 Jun;76(6):1624-1628

Basophil Activation Test for Allergy Diagnosis

Doña I, Ariza A, Fernández TD, Torres MJ Journal of visualized experiments : JoVE 2021 May 31;(171):

Beta-lactam-induced immediate hypersensitivity reactions: A genome-wide association study of a deeply phenotyped cohort

Nicoletti P, Carr DF, Barrett S, McEvoy L, Friedmann PS, et al. The Journal of allergy and clinical immunology 2021 May;147(5):1830-1837.e15

Editorial: Drug Hypersensitivity: From Mechanisms to Improved Diagnosis and Standards of Care

Fernandez TD, Torres MJ, Romano A Frontiers in pharmacology 2021;12():718928

Clinical Approach to Mast Cell Activation Syndrome: A Practical Overview

Matito A, Escribese MM, Longo N, Mayorga C, Luengo-Sánchez O, et al. Journal of investigational allergology & clinical immunology 2021 Dec 21;31(6):461-470

Clinical Practice Guidelines for Diagnosis and Management of Hypersensitivity Reactions to Quinolones

Doña I, Blanca-López N, Boteanu C, Cueva-Oliver B, Fernández-Sánchez FJ, et al. Journal of investigational allergology & clinical immunology 2021 Jul 26;31(4):292-307

COVID-19 pandemic: Practical considerations on the organization of an allergy clinic-An EAACI/ARIA Position Paper

Pfaar O, Klimek L, Jutel M, Akdis CA, Bousquet J, et al. Allergy 2021 Mar;76(3):648-676

Deep sequencing of prostaglandin-endoperoxide synthase (PTGE) genes reveals genetic susceptibility for cross-reactive hypersensitivity to NSAID

García-Martín E, García-Menaya JM, Esguevillas G, Cornejo-García JA, Doña I, et al. British journal of pharmacology 2021 Mar;178(5):1218-1233

Dendritic cells inclusion and cell-subset assessment improve flow-cytometry-based proliferation test in non-immediate drug hypersensitivity reactions

Fernandez-Santamaria R, Bogas G, Palomares F, Salas M, Fernandez TD, et al. Allergy 2021 Jul;76(7):2123-2134

Medical algorithm: Diagnosis and treatment of local allergic rhinitis

Eguiluz-Gracia I, Testera-Montes A, Rondon C Allergy 2021 Sep;76(9):2927-2930

Diagnostic Approach of Hypersensitivity Reactions to Cefazolin in a Large Prospective Cohort

Bogas G, Doña I, Dionicio J, Fernández TD, Mayorga C, et al. The journal of allergy and clinical immunology. In practice 2021 Dec;9(12):4421-4430.e4

EAACI statement on the diagnosis, management and prevention of severe allergic reactions to COVID-19 vaccines

Sokolowska M, Eiwegger T, Ollert M, Torres MJ, Barber D, et al. Allergy 2021 Jun;76(6):1629-1639

Recent patents in Allergy/Immunology: New pyrazinones for the diagnosis of allergies to aminocephalosporins

Martin-Serrano A, Perez-Inestrosa E, Mayorga C, Torres MJ, Montañez MI Allergy 2021 Apr;76(4):1288-1291

Epigenetics in Food Allergy and Immunomodulation

Cañas JA, Núñez R, Cruz-Amaya A, Gómez F, Torres MJ, et al. Nutrients 2021 Dec 1;13(12):

Food-dependent NSAID-induced hypersensitivity (FDNIH) reactions: Unraveling the clinical features and risk factors

Sánchez-López J, Araujo G, Cardona V, García-Moral A, Casas-Saucedo R, et al. Allergy 2021 May;76(5):1480-1492

The complexity of drug hypersensitivity reactions

Torres MJ, Torres MJ Allergy 2021 Apr;76(4):985-987

Genetic Variants in Cytosolic Phospholipase A2 Associated With Nonsteroidal Anti-Inflammatory Drug-Induced Acute Urticaria/Angioedema

Jurado-Escobar R, Doña I, Triano-Cornejo J, Perkins JR, Pérez-Sánchez N, et al. Frontiers in pharmacology 2021;12():667824

Genetic Variants of Alcohol Metabolizing Enzymes and Alcohol-Related Liver Cirrhosis Risk

Ayuso P, García-Martín E, Cornejo-García JA, Agúndez JAG, Ladero JM Journal of personalized medicine 2021 May 13;11(5):

Hypersensitivity reactions and anaphylaxis to checkpoint inhibitor- monoclonal antibodies and desensitization

Labella M, Castells M Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2021 Jun;126(6):623-629

Hypersensitivity Reactions to Cancer Chemotherapy: Practical Recommendations of ARADyAL for Diagnosis and Desensitization

Vega A, Jimenez-Rodriguez TW, Barranco R, Bartra J, Diéguez MC, et al. Journal of investigational allergology & clinical immunology 2021 Oct 25;31(5):364-384

IgE-Reactivity Pattern of Tomato Seed and Peel Nonspecific Lipid-Transfer Proteins after in Vitro Gastrointestinal Digestion

Martín-Pedraza L, Mayorga C, Gomez F, Bueno-Díaz C, Blanca-Lopez N, et al. Journal of agricultural and food chemistry 2021 Mar 24;69(11):3511-3518

Immune-Mediated Mechanisms in Cofactor-Dependent Food Allergy and Anaphylaxis: Effect of Cofactors in Basophils and Mast Cells

Muñoz-Cano R, San Bartolome C, Casas-Saucedo R, Araujo G, Gelis S, et al. Frontiers in immunology 2020;11():623071

Immunomodulatory Response of Toll-like Receptor Ligand-Peptide Conjugates in Food Allergy

Losada Méndez J, Palomares F, Gómez F, Ramírez-López P, Ramos-Soriano J, et al. ACS chemical biology 2021 Nov 19;16(11):2651-2664

Lack of Major Involvement of Common CYP2C Gene Polymorphisms in the Risk of Developing Cross-Hypersensitivity to NSAIDs

Macías Y, García-Menaya JM, Martí M, Cordobés C, Jurado-Escobar R, et al. Frontiers in pharmacology 2021;12():648262

Local Respiratory Allergy: From Rhinitis Phenotype to Disease Spectrum

Testera-Montes A, Salas M, Palomares F, Ariza A, Torres MJ, et al. Frontiers in immunology 2021;12():691964

Management of anaphylaxis due to COVID-19 vaccines in the elderly

Bousquet J, Agache I, Blain H, Jutel M, Ventura MT, et al. Allergy 2021 Oct;76(10):2952-2964

Management of patients with chronic rhinosinusitis during the COVID-19 pandemic-An EAACI position paper

Klimek L, Jutel M, Bousquet J, Agache I, Akdis CA, et al. Allergy 2021 Mar;76(3):677-688

Multiepitope Dendrimeric Antigen-Silica Particle Composites as Nano-Based Platforms for Specific Recognition of IgEs

Gil-Ocaña V, Jimenez IM, Mayorga C, Doña I, Céspedes JA, et al. Frontiers in immunology 2021;12():750109

Nanoarchitectures for efficient IgE cross-linking on effector cells to study amoxicillin allergy

Tesfaye A, Rodríguez-Nogales A, Benedé S, Fernández TD, Paris JL, et al. Allergy 2021 Oct;76(10):3183-3193

Epithelial Permeability to Ole e 1 Is More Dependent on the Functional State of the Bronchial Epithelium Than on the Activity of Der p 1 Protease Acting as an Adjuvant to the Bystander Allergen

López-Rodríguez JC, González M, Bogas G, Mayorga C, Villalba M, et al. Journal of investigational allergology & clinical immunology 2021 Jul 26;31(4):343-346

New Insights in Therapy for Food Allergy

Mayorga C, Palomares F, Cañas JA, Pérez-Sánchez N, Núñez R, et al. Foods (Basel, Switzerland) 2021 May 10;10(5):

Non-specific lipid-transfer proteins: Allergen structure and function, cross-reactivity, sensitization, and epidemiology

Skypala IJ, Asero R, Barber D, Cecchi L, Diaz Perales A, et al. Clinical and translational allergy 2021 May;11(3):e12010

Ocular side effects of checkpoint inhibitors

Alba-Linero C, Alba E Survey of ophthalmology 2021 Nov-Dec;66(6):951-959

Polymorphisms in eicosanoid-related biosynthesis enzymes associated with acute urticaria/angioedema induced by nonsteroidal anti-inflammatory drug hypersensitivity

Jurado-Escobar R, Doña I, Perkins JR, Laguna JJ, Muñoz-Cano R, et al. The British journal of dermatology 2021 Oct;185(4):815-824

Practice parameters for diagnosing and managing iodinated contrast media hypersensitivity

Torres MJ, Trautmann A, Böhm I, Scherer K, Barbaud A, et al. Allergy 2021 May;76(5):1325-1339

PTGDR2 Expression in Peripheral Blood as a Potential Biomarker in Adult Patients with Asthma

García-Sánchez A, Estravís M, Martin MJ, Pérez-Pazos J, Martín-García C, et al. Journal of personalized medicine 2021 Aug 24;11(9):

Metabolomics in the Identification of Biomarkers of Asthma

Villaseñor A, Eguiluz-Gracia I, Moreira A, Wheelock CE, Escribese MM Metabolites 2021 May 29;11(6):

Real-life impact of COVID-19 pandemic lockdown on the management of pediatric and adult asthma: A survey by the EAACI Asthma Section

Eguiluz-Gracia I, van den Berge M, Boccabella C, Bonini M, Caruso C, et al. Allergy 2021 Sep;76(9):2776-2784

Single-dose prolonged drug provocation test, without previous skin testing, is safe for diagnosing children with mild non-immediate reactions to beta-lactams

Prieto A, Muñoz C, Bogas G, Fernández-Santamaría R, Palomares F, et al. Allergy 2021 Aug;76(8):2544-2554

Subjects develop tolerance to Pru p 3 but respiratory allergy to Pru p 9: A large study group from a peach exposed population

Somoza ML, Pérez-Sánchez N, Victorio-Puche L, Martín-Pedraza L, Esteban Rodríguez A, et al. PloS one 2021;16(8):e0255305

Systematic evaluation of allergic phenotypes of rhinitis in children and adolescents

Prieto A, Rondón C, Eguiluz-Gracia I, Muñoz C, Testera-Montes A, et al. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2021 Jul;32(5):953-962

Targeted inhibition of allergen-induced histamine production by neutrophils

Chacón P, Vega-Rioja A, Doukkali B, Del Valle Rodríguez A, Bellido V, et al. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21483

Seasonal Administration of Omalizumab in Patients With Uncontrolled Asthma and Sensitization to Olive Pollen

Serrano P, Navas A, Ruiz-León B, Herrero L, Rondón C, et al. Journal of investigational allergology & clinical immunology 2021 Oct 25;31(5):436-438

The diagnosis and management of allergic reactions in patients sensitized to non-specific lipid transfer proteins

Skypala IJ, Bartra J, Ebo DG, Antje Faber M, Fernández-Rivas M, et al. Allergy 2021 Aug;76(8):2433-2446

The Role of Benzylpenicilloyl Epimers in Specific IgE Recognition

Mayorga C, Montañez MI, Najera F, Bogas G, Fernandez TD, et al. Frontiers in pharmacology 2021;12():585890

Tomographic and aberrometric assessment of first-time diagnosed paediatric keratoconus based on age ranges: a multicentre study

Rocha-de-Lossada C, Prieto-Godoy M, Sánchez-González JM, Romano V, Borroni D, et al. Acta ophthalmologica 2021 Sep;99(6):e929-e936

Treating Through Drug-Associated Exanthems in Drug Allergy Management: Current Evidence and Clinical Aspects

Trubiano JA, Soria A, Torres MJ, Trautmann A The journal of allergy and clinical immunology. In practice 2021 Aug;9(8):2984-2993

Use of ultra-wide field retinal imaging and optical coherence tomography angiography in the diagnosis of incomplete Susac syndrome

Alba-Linero C, Liscombe-Sepúlveda JP, Llorenç V, GiraltJosa J, Adán A European journal of ophthalmology 2021 Nov;31(6):3238-3247

Uveitic macular edema response to intravitreal dexamethasone implant is independent of optical coherence tomography findings

Moll-Udina A, Figueras-Roca M, Oliveres J, Sala-Puigdollers A, Esquinas C, et al. International ophthalmology 2021 Mar;41(3):787-796

Vaccines and Allergic reactions: The past, the current COVID-19 pandemic, and future perspectives

Sampath V, Rabinowitz G, Shah M, Jain S, Diamant Z, et al. Allergy 2021 Jun;76(6):1640-1660

Viral Infections and Cutaneous Drug-Related Eruptions

Anci E, Braun C, Marinosci A, Rodieux F, Midun E, et al. Frontiers in pharmacology 2020;11():586407

You might owe your mother more than you think

de Las Vecillas L, Eguiluz-Gracia I, Giovannini M Allergy 2021 Oct;76(10):3236-3237

A compendium answering 150 questions on COVID-19 and SARS-CoV-2

Riggioni C, Comberiati P, Giovannini M, Agache I, Akdis M, et al. Allergy 2020 Oct;75(10):2503-2541

Advances and novel developments in drug hypersensitivity diagnosis

Ariza A, Mayorga C, Bogas G, Barrionuevo E, Torres MJ, et al. Allergy 2020 Dec;75(12):3112-3123

Allergen Immunotherapy for Local Respiratory Allergy

Eguiluz-Gracia I, Ariza A, Testera-Montes A, Rondón C, Campo P Current allergy and asthma reports 2020 May 19;20(7):23

Amoxicillin Inactivation by Thiol-Catalyzed Cyclization Reduces Protein Haptenation and Antibacterial Potency

Pajares MA, Zimmerman T, Sánchez-Gómez FJ, Ariza A, Torres MJ, et al. Frontiers in pharmacology 2020;11():189

Analysis of the Costs Associated With the Elective Evaluation of Patients Labelled as Allergic to Beta-Lactams or Nonsteroidal Antiinflamatory Agents

Sobrino-García M, Moreno EM, Muñoz-Bellido FJ, Gracia-Bara MT, Laffond E, et al. Frontiers in pharmacology 2020;11():584633

Atopy Can Be an Interfering Factor in Genetic Association Studies of beta-Lactam Allergy

Rivera-Reigada ML, Moreno E, Sanz C, García-Sánchez A, Cornejo-García JA, et al. Journal of investigational allergology & clinical immunology 2020;30(1):63-65

Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis: an EAACI position paper

Hox V, Lourijsen E, Jordens A, Aasbjerg K, Agache I, et al. Clinical and translational allergy 2020;10():1

Biomarkers for diagnosis and prediction of therapy responses in allergic diseases and asthma

Breiteneder H, Peng YQ, Agache I, Diamant Z, Eiwegger T, et al. Allergy 2020 Dec;75(12):3039-3068

Biotin-Labelled Clavulanic Acid to Identify Proteins Target for Haptenation in Serum: Implications in Allergy Studies

Martín-Serrano Á, Gonzalez-Morena JM, Barbero N, Ariza A, Sánchez Gómez FJ, et al. Frontiers in pharmacology 2020;11():594755

Characterization of amoxicillin and clavulanic acid specific T-cell clones from patients with immediate drug hypersensitivity

Ariza A, Fernández-Santamaría R, Meng X, Salas M, Ogese MO, et al. Allergy 2020 Oct;75(10):2562-2573

Clinical Characterization and Diagnostic Approaches for Patients Reporting Hypersensitivity Reactions to Quinolones

Doña I, Pérez-Sánchez N, Salas M, Barrionuevo E, Ruiz-San Francisco A, et al. The journal of allergy and clinical immunology. In practice 2020 Sep;8(8):2707-2714.e2

Coexistence of nasal reactivity to allergens with and without IgE sensitization in patients with allergic rhinitis

Eguiluz-Gracia I, Fernandez-Santamaria R, Testera-Montes A, Ariza A, Campo P, et al. Allergy 2020 Jul;75(7):1689-1698

Corneal Fleck dystrophy in a Spanish family

Rocha-de-Lossada C, Alba-Linero C, Hernando Ayala C, Rodriguez-Calvo-de-Mora M Indian journal of ophthalmology 2020 May;68(5):918

Der p 1-based immunotoxin as potential tool for the treatment of dust mite respiratory allergy

Lázaro-Gorines R, López-Rodríguez JC, Benedé S, González M, Mayorga C, et al. Scientific reports 2020 Jul 23;10(1):12255

Design of an antigenic determinant of cefaclor: Chemical structure-IgE recognition relationship

Martín-Serrano A, Mayorga C, Barrionuevo E, Pérez N, Romano A, et al. The Journal of allergy and clinical immunology 2020 Apr;145(4):1301-1304.e4

Diagnosis and management of the drug hypersensitivity reactions in Coronavirus disease 19

Gelincik A, Brockow K, Çelik GE, Doña I, Mayorga C, et al. Allergy 2020 Nov;75(11):2775-2793

Diagnostic criteria for acute FPIES: What are we missing?

Vazquez-Ortiz M, Argiz L, Machinena A, Echeverria L, Blasco C, et al. The journal of allergy and clinical immunology. In practice 2020 May;8(5):1717-1720.e2

EAACI position paper on how to classify cutaneous manifestations of drug hypersensitivity

Brockow, K; Ardern-Jones, MR; Mockenhaupt, M; Aberer, W; Barbaud, A; Caubet, JC; Spiewak, R; Torres, MJ; Mortz, CG ALLERGOLOGIE 2020

Evaluation of Subjects Experiencing Allergic Reactions to Non-Steroidal Anti-Inflammatory Drugs: Clinical Characteristics and Drugs Involved

Pérez-Sánchez N, Doña I, Bogas G, Salas M, Testera A, et al. Frontiers in pharmacology 2020;11():503

FENOMA Study: Achieving Full Control in Patients with Severe Allergic Asthma

Cabrejos S, Moreira A, Ramirez A, Quirce S, Soto Campos G, et al. Journal of asthma and allergy 2020;13():159-166

GNAI2 variants predict nonsteroidal anti-inflammatory drug hypersensitivity in a genome-wide study

Blanca M, Oussalah A, Cornejo-García JA, Blanca-López N, Guéant-Rodriguez RM, et al. Allergy 2020 May;75(5):1250-1253

Hypersensitivity Reactions to Multiple Iodinated Contrast Media

Doña I, Bogas G, Salas M, Testera A, Moreno E, et al. Frontiers in pharmacology 2020;11():575437

Intradermal Tests With Drugs: An Approach to Standardization

Barbaud A, Weinborn M, Garvey LH, Testi S, Kvedariene V, et al. Frontiers in medicine 2020;7():156

Local allergic rhinitis: a pediatric perspective

Beken B, Eguiluz-Gracia I, Yazicioglu M, Campo P The Turkish journal of pediatrics 2020;62(5):701-710

Medical algorithm: Diagnosis and treatment of nonsteroidal antiinflammatory drugs hypersensitivity

Doña I, Pérez-Sánchez N, Bogas G, Moreno E, Salas M, et al. Allergy 2020 Apr;75(4):1003-1005

Naphthalimide Dyes with Orthogonal Functional Groups for Click Chemistry: Attachment to Solid Supports and Applications in Drug Allergy Diagnosis

Ruiz-Sanchez AJ, Collado D, Mayorga C, Torres MJ, Perez-Inestrosa E ChemPlusChem 2020 Apr;85(4):689-693

Ocular surface characterization after allogeneic stem cell transplantation: A prospective study in a referral center

Alba-Linero C, Rodriguez Calvo de Mora M, Lavado Valenzuela R, Pascual Cascón MJ, Martín Cerezo AR, et al. Indian journal of ophthalmology 2020 Aug;68(8):1556-1562

Omega-3 fatty acids and the regulation of adipogenesis

Eguiluz-Gracia I, Bogas G Allergy 2020 May;75(5):1281-1282

Penicillin and cephalosporin cross-reactivity: role of side chain and synthetic cefadroxil epitopes

Bogas G, Mayorga C, Martín-Serrano Á, Fernández-Santamaría R, Jiménez-Sánchez IM, et al. Clinical and translational allergy 2020 Dec 4;10(1):57

Peptide Glycodendrirners as Potential Vaccines for Olive Pollen Allergy

Benedé S, Ramos-Soriano J, Palomares F, Losada J, Mascaraque A, et al. Molecular pharmaceutics 2020 Mar 2;17(3):827-836

Phenotyping peach-allergic patients sensitized to LTP and analysing severity biomarkers

Bogas G, Muñoz-Cano R, Mayorga C, Casas R, Bartra J, et al. Allergy 2020 Dec;75(12):3228-3236

Platelet-Adherent Leukocytes Associated With Cutaneous Cross-Reactive Hypersensitivity to Nonsteroidal Anti-Inflammatory Drugs

Jurado-Escobar R, Doña I, Bogas-Herrera G, Pérez-Sánchez N, Salas M, et al. Frontiers in pharmacology 2020;11():594427

Practical Guidance for the Evaluation and Management of Drug Hypersensitivity: Specific Drugs

Broyles AD, Banerji A, Barmettler S, Biggs CM, Blumenthal K, et al. The journal of allergy and clinical immunology. In practice 2020 Oct;8(9S):S16-S116

Precision Medicine in House Dust Mite-Driven Allergic Asthma

Eguiluz-Gracia I, Palomares F, Salas M, Testera-Montes A, Ariza A, et al. Journal of clinical medicine 2020 Nov 26;9(12):

Progress in understanding hypersensitivity reactions to nonsteroidal anti-inflammatory drugs

Doña I, Pérez-Sánchez N, Eguiluz-Gracia I, Muñoz-Cano R, Bartra J, et al. Allergy 2020 Mar;75(3):561-575

Promoter Genotyping and mRNA Expression-Based Analysis of the PTGDR Gene in Allergy

San Segundo-Val I, García-Sánchez A, Sanz C, Cornejo-García JA, Isidoro-García M, et al. Journal of investigational allergology & clinical immunology 2020 Apr 24;30(2):117-126

Protein Binding of Lapatinib and Its N- and O-Dealkylated Metabolites Interrogated by Fluorescence, Ultrafast Spectroscopy and Molecular Dynamics Simulations

Andreu I, Lence E, González-Bello C, Mayorga C, Cuquerella MC, et al. Frontiers in pharmacology 2020;11():576495

Spanish Guidelines for Diagnosis, Management, Treatment, and Prevention of DRESS Syndrome

Cabañas R, Ramírez E, Sendagorta E, Alamar R, Barranco R, et al. Journal of investigational allergology & clinical immunology 2020;30(4):229-253

Statement of the Spanish Society of Allergology and Clinical Immunology on Provocation Tests With Aspirin/Nonsteroidal Anti-inflammatory Drugs

Izquierdo-Domínguez A, Bobolea I, Doña I, Campo P, Segura C, et al. Journal of investigational allergology & clinical immunology 2020;30(1):1-13

The need for clean air: The way air pollution and climate change affect allergic rhinitis and asthma

Eguiluz-Gracia I, Mathioudakis AG, Bartel S, Vijverberg SJH, Fuertes E, et al. Allergy 2020 Sep;75(9):2170-2184

Towards a more precise diagnosis of hypersensitivity to beta-lactams – an EAACI position paper

Romano A, Atanaskovic-Markovic M, Barbaud A, Bircher AJ, Brockow K, et al. Allergy 2020 Jun;75(6):1300-1315

A EAACI drug allergy interest group survey on how European allergy specialists deal with beta-lactam allergy

Torres MJ, Celik GE, Whitaker P, Atanaskovic-Markovic M, Barbaud A, et al. Allergy 2019 Jun;74(6):1052-1062

Accuracy of the Diagnosis of Allergic Reactions in the Emergency Department

Lacombe-Barrios J, Gómez F, Pérez N, Barrionuevo E, Doña I, et al. Journal of investigational allergology & clinical immunology 2019;29(3):222-230

An Update on the Immunological, Metabolic and Genetic Mechanisms in Drug Hypersensitivity Reactions

Mayorga C, Montañez MI, Jurado-Escobar R, Gil-Ocaña V, Cornejo-García JA Current pharmaceutical design 2019;25(36):3813-3828

Bronchial asthma triggered by house dust mites in patients with local allergic rhinitis

Campo P, Eguiluz-Gracia I, Plaza-Serón MC, Salas M, José Rodríguez M, et al. Allergy 2019 Aug;74(8):1502-1510

Comparing biologicals and small molecule drug therapies for chronic respiratory diseases: An EAACI Taskforce on Immunopharmacology position paper

Roth-Walter F, Adcock IM, Benito-Villalvilla C, Bianchini R, Bjermer L, et al. Allergy 2019 Mar;74(3):432-448

Controversies in Drug Allergy: Beta-Lactam Hypersensitivity Testing

Torres MJ, Adkinson NF Jr, Caubet JC, Khan DA, Kidon MI, et al. The journal of allergy and clinical immunology. In practice 2019 Jan;7(1):40-45

Diagnosis and management of NSAID-Exacerbated Respiratory Disease (N-ERD)a EAACI position paper

Kowalski ML, Agache I, Bavbek S, Bakirtas A, Blanca M, et al. Allergy 2019 Jan;74(1):28-39

EAACI position paper on how to classify cutaneous manifestations of drug hypersensitivity

Brockow K, Ardern-Jones MR, Mockenhaupt M, Aberer W, Barbaud A, et al. Allergy 2019 Jan;74(1):14-27

Early Biomarkers for Severe Drug Hypersensitivity Reactions

Ariza A, Torres MJ, Moreno-Aguilar C, Fernández-Santamaría R, Fernández TD Current pharmaceutical design 2019;25(36):3829-3839

Eicosanoid mediator profiles in different phenotypes of nonsteroidal anti-inflammatory drug-induced urticaria

Doña I, Jurado-Escobar R, Perkins JR, Ayuso P, Plaza-Serón MC, et al. Allergy 2019 Jun;74(6):1135-1144

Expression of the Tim3-galectin-9 axis is altered in drug-induced maculopapular exanthema

Fernandez-Santamaría R, Palomares F, Salas M, Doña I, Bogas G, et al. Allergy 2019 Sep;74(9):1769-1779

Future research trends in understanding the mechanisms underlying allergic diseases for improved patient care.

Breiteneder H, Diamant Z, Eiwegger T, Fokkens WJ, Traidl-Hoffmann C, et al. Allergy 2019 Dec;74(12):2293-2311

Glycosylated nanostructures in sublingual immunotherapy induce long-lasting tolerance in LTP allergy mouse model

Rodriguez MJ, Ramos-Soriano J, Perkins JR, Mascaraque A, Torres MJ, et al. Scientific reports 2019 Mar 11;9(1):4043

How to Diagnose and Treat Local Allergic Rhinitis: A Challenge for Clinicians

Eguiluz-Gracia I, Pérez-Sánchez N, Bogas G, Campo P, Rondón C Journal of clinical medicine 2019 Jul 19;8(7):

ICER report for peanut OIT comes up short

Eiwegger T, Anagnostou K, Arasi S, Bégin P, Ben-Shoshan M, et al. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2019 Nov;123(5):430-432

Identification of an antigenic determinant of clavulanic acid responsible for IgE-mediated reactions

Barbero N, Fernández-Santamaría R, Mayorga C, Martin-Serrano Á, Salas M, et al. Allergy 2019 Aug;74(8):1490-1501

Local allergic rhinitis: Implications for management

Campo P, Eguiluz-Gracia I, Bogas G, Salas M, Plaza Serón C, et al. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2019 Jan;49(1):6-16

Management of ocular allergy

Leonardi A, Silva D, Perez Formigo D, Bozkurt B, Sharma V, et al. Allergy 2019 Sep;74(9):1611-1630

Mucosal IgE immune responses in respiratory diseases

Eguiluz-Gracia I, Layhadi JA, Rondon C, Shamji MH Current opinion in pharmacology 2019 Jun;46():100-107

Polymorphisms in CEP68 gene associated with risk of immediate selective reactions to non-steroidal anti-inflammatory drugs

Perkins JR, Acosta-Herrera M, Plaza-Serón MC, Jurado-Escobar R, Doña I, et al. The pharmacogenomics journal 2019 Apr;19(2):191-199

Pru p 3-Glycodendropeptides Based on Mannoses Promote Changes in the Immunological Properties of Dendritic and T-Cells from LTP-Allergic Patients

Palomares F, Ramos-Soriano J, Gomez F, Mascaraque A, Bogas G, et al. Molecular nutrition & food research 2019 Oct;63(20):e1900553

PSEUDOVITELLIFORM MACULOPATHY SECONDARY TO BRAF AND MEK INHIBITORS IN A PATIENT WITH METASTASIC MELANOMA

Alba-Linero C, Rocha De Lossada C, Delgado-Fernández AS, Jódar-Márquez M, Rodríguez Calvo De Mora M, et al. Journal of biological regulators and homeostatic agents 2019 September-October,;33(5):1497-1500

Quality of Life in Patients with Allergic Reactions to Medications: Influence of a Drug Allergy Evaluation

Gastaminza G, Ruiz-Canela M, Andrés-López B, Barasona Villarejo MJ, Cabañas R, et al. The journal of allergy and clinical immunology. In practice 2019 Nov – Dec;7(8):2714-2721

Recent developments and highlights in drug hypersensitivity

Mayorga C, Fernandez TD, Montañez MI, Moreno E, Torres MJ Allergy 2019 Dec;74(12):2368-2381

Role of IL-35 in sublingual allergen immunotherapy

Layhadi JA, Eguiluz-Gracia I, Shamji MH Current opinion in allergy and clinical immunology 2019 Feb;19(1):12-17

Safety and reproducibility of nasal allergen challenge

Eguiluz-Gracia I, Testera-Montes A, González M, Pérez-Sánchez N, Ariza A, et al. Allergy 2019 Jun;74(6):1125-1134

Severe asthma phenotypes in patients controlled with omalizumab: A real-world study

Campo P, Soto Campos G, Aparicio MB, Jorge AM, González Expósito HM, et al. Respiratory medicine 2019 Nov;159():105804

Transcriptional Profiling of Dendritic Cells in a Mouse Model of Food-Antigen-Induced Anaphylaxis Reveals the Upregulation of Multiple Immune-Related Pathways

Rodriguez MJ, Palomares F, Bogas G, Torres MJ, Diaz-Perales A, et al. Molecular nutrition & food research 2019 Feb;63(3):e1800759

A recombinant isoform of the Ole e 7 olive pollen allergen assembled by de novo mass spectrometry retains the allergenic ability of the natural allergen

Oeo-Santos C, Mas S, Benedé S, López-Lucendo M, Quiralte J, et al. Journal of proteomics 2018 Sep 15;187():39-46

An EAACI task force report: recognising the potential of the primary care physician in the diagnosis and management of drug hypersensitivity

Doña I, Caubet JC, Brockow K, Doyle M, Moreno E, et al. Clinical and translational allergy 2018;8():16

Asthma and allergic rhinitis associate with the rs2229542 variant that induces a p.Lys90Glu mutation and compromises AKR1B1 protein levels

García-Martín E, Sánchez-Gómez FJ, Amo G, García Menaya J, Cordobés C, et al. Human mutation 2018 Aug;39(8):1081-1091

Dendrimeric Antigens for Drug Allergy Diagnosis: A New Approach for Basophil Activation Tests

Molina N, Martin-Serrano A, Fernandez TD, Tesfaye A, Najera F, et al. Molecules (Basel, Switzerland) 2018 Apr 24;23(5):

Design of multivalent fluorescent dendritic probes for site-specific labeling of biomolecules

Ortiz, AMS; Stenstrom, P; Antunez, PM; Andren, OCJ; Torres, MJ; Montanez, MI; Malkoch, M JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY 2018

Diagnosing and managing patients with drug hypersensitivity

Fernandez J, Doña I Expert review of clinical immunology 2018 Jan;14(1):29-41

Direct intranasal application of the solid phase of ImmunoCAP (R) increases nasal specific immunoglobulin E detection in local allergic rhinitis patients

Campo P, Del Carmen Plaza-Seron M, Eguiluz-Gracia I, Verge J, Galindo L, et al. International forum of allergy & rhinology 2018 Jan;8(1):15-19

EAACI Position paper on the standardization of nasal allergen challenges

Augé J, Vent J, Agache I, Airaksinen L, Campo Mozo P, et al. Allergy 2018 Aug;73(8):1597-1608

Elemental and optical imaging evaluation of zwitterionic gold nanoclusters in glioblastoma mouse models

Le Guével X, Henry M, Motto-Ros V, Longo E, Montañez MI, et al. Nanoscale 2018 Oct 21;10(39):18657-18664

IgE Test in Secretions of Patients with Respiratory Allergy

Rondón C, Eguíluz-Gracia I, Shamji MH, Layhadi JA, Salas M, et al. Current allergy and asthma reports 2018 Oct 13;18(12):67

Immunological Changes Induced in Peach Allergy Patients with Systemic Reactions by Pru p 3 Sublingual Immunotherapy

Palomares F, Gomez F, Bogas G, Campo P, Perkins JR, et al. Molecular nutrition & food research 2018 Feb;62(3):

Immunotherapy with Native Molecule rather than Hypoallergenic Variant of Pru p 3, the Major Peach Allergen, Shows Beneficial Effects in Mice

Rodriguez MJ, Wangorsch A, Gomez F, Schülke S, Torres MJ, et al. Journal of immunology research 2018;2018():3479185

International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis

Wise SK, Lin SY, Toskala E, Orlandi RR, Akdis CA, et al. International forum of allergy & rhinology 2018 Feb;8(2):108-352

Is the evidence of local allergic rhinitis growing?

Rondón C, Eguiluz-Gracia I, Campo P Current opinion in allergy and clinical immunology 2018 Aug;18(4):342-349

Local allergic rhinitis is an independent rhinitis phenotype: The results of a 10-year follow-up study

Rondon C, Campo P, Eguiluz-Gracia I, Plaza C, Bogas G, et al. Allergy 2018 Feb;73(2):470-478

Microbiome and Allergic Diseases

Pascal M, Perez-Gordo M, Caballero T, Escribese MM, Lopez Longo MN, et al. Frontiers in immunology 2018;9():1584

Missense Gamma-Aminobutyric Acid Receptor Polymorphisms Are Associated with Reaction Time, Motor Time, and Ethanol Effects in Vivo

García-Martín E, Ramos MI, Cornejo-García JA, Galván S, Perkins JR, et al. Frontiers in cellular neuroscience 2018;12():10

NSAIDs-hypersensitivity often induces a blended reaction pattern involving multiple organs

Doña I, Barrionuevo E, Salas M, Laguna JJ, Agúndez J, et al. Scientific reports 2018 Nov 12;8(1):16710

Occupational hypersensitivity pneumonitis: an EAACI position paper

Quirce, S; Vandenplas, O; Campo, P; Cruz, MJ; de Blay, F; Koschel, D; Moscato, G; Pala, G; Raulf, M; Sastre, J; Siracusa, A; Tarlo, SM; Walusiak-Skorupa, J; Cormier, Y ALLERGOLOGIE 2018

Practical Guidelines for Perioperative Hypersensitivity Reactions

Laguna JJ, Archilla J, Doña I, Corominas M, Gastaminza G, et al. Journal of investigational allergology & clinical immunology 2018;28(4):216-232

Recent developments and highlights in biomarkers in allergic diseases and asthma

Eguiluz-Gracia I, Tay TR, Hew M, Escribese MM, Barber D, et al. Allergy 2018 Dec;73(12):2290-2305

The Basophil Activation Test Can Be of Value for Diagnosing Immediate Allergic Reactions to Omeprazole

Laguna JJ, Bogas G, Salas M, Mayorga C, Dionicio J, et al. The journal of allergy and clinical immunology. In practice 2018 Sep – Oct;6(5):1628-1636.e2

The roadmap for allergology in Europe: The subspecialty of allergology as “stop-over” on the way to a full specialty. An EAACI position statement

Gerth van Wijk R., Eguiluz-Gracia I., Gayraud J., Gutermuth J., Hamelmann E., Heffler E., Popov T.A., Schmid-Grendelmeier P., Tomazic P.V., Tsilochristou O., Muelleneisen N. ALLERGY 2018

The urgent need for a harmonized severity scoring system for acute allergic reactions

Muraro A, Fernandez-Rivas M, Beyer K, Cardona V, Clark A, et al. Allergy 2018 Sep;73(9):1792-1800

Use of the Basophil Activation Test May Reduce the Need for Drug Provocation in Amoxicillin-Clavulanic Allergy

Salas M, Fernández-Santamaría R, Mayorga C, Barrionuevo E, Ariza A, et al. The journal of allergy and clinical immunology. In practice 2018 May – Jun;6(3):1010-1018.e2

What can we learn in drug allergy management from World Health Organization’s international classifications?

Tanno LK, Torres MJ, Castells M, Demoly P, Joint Allergy Academies. Allergy 2018 May;73(5):987-992

Widening control of fin inter-rays in zebrafish and inferences about actinopterygian fins

Murciano C, Cazorla-Vázquez S, Gutiérrez J, Hijano JA, Ruiz-Sánchez J, et al. Journal of anatomy 2018 May;232(5):783-805

Alcohol hyper-responsiveness in chronic rhinosinusitis with nasal polyps

De Schryver E, Derycke L, Campo P, Gabriels E, Joos GF, et al. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2017 Feb;47(2):245-253

Alternative Anaphylactic Routes: The Potential Role of Macrophages

Escribese MM, Rosace D, Chivato T, Fernández TD, Corbí AL, et al. Frontiers in immunology 2017;8():515

Amoxicillin haptenates intracellular proteins that can be transported in exosomes to target cells

Sánchez-Gómez FJ, González-Morena JM, Vida Y, Pérez-Inestrosa E, Blanca M, et al. Allergy 2017 Mar;72(3):385-396

Approach to the diagnosis of drug hypersensitivity reactions: similarities and differences between Europe and North America

Torres MJ, Romano A, Celik G, Demoly P, Khan DA, et al. Clinical and translational allergy 2017;7():7

Conjunctival allergen provocation test : guidelines for daily practice

Fauquert JL, Jedrzejczak-Czechowicz M, Rondon C, Calder V, Silva D, et al. Allergy 2017 Jan;72(1):43-54

Dermatophagoides pteronyssinus immunotherapy changes the T-regulatory cell activity

Gonzalez M, Doña I, Palomares F, Campo P, Rodriguez MJ, et al. Scientific reports 2017 Sep 20;7(1):11949

Diagnostic tools in ocular allergy

Leonardi A, Doan S, Fauquert JL, Bozkurt B, Allegri P, et al. Allergy 2017 Oct;72(10):1485-1498

Epidemiology, Mechanisms, and Diagnosis of Drug-Induced Anaphylaxis

Montañez MI, Mayorga C, Bogas G, Barrionuevo E, Fernandez-Santamaria R, et al. Frontiers in immunology 2017;8():614

Estimate of the total costs of allergic rhinitis in specialized care based on real-world data: the FERIN Study

Colás C, Brosa M, Antón E, Montoro J, Navarro A, et al. Allergy 2017 Jun;72(6):959-966

Evolution of diagnostic approaches in betalactam hypersensitivity

Fernandez TD, Mayorga C, Salas M, Barrionuevo E, Posadas T, et al. Expert review of clinical pharmacology 2017 Jun;10(6):671-683

Hydrophobicity of Gold Nanoclusters Influences Their Interactions with Biological Barriers

Porret, E; Sancey, L; Martin-Serrano, A; Montanez, MI; Seeman, R; Yahia-Arnmar, A; Okuno, H; Gomez, F; Ariza, A; Hildebrandt, N; Fleury, JB; Coll, JL; Le Guevel, X CHEMISTRY OF MATERIALS 2017

Immediate Reactions to More Than 1 NSAID Must Not Be Considered Cross-Hypersensitivity Unless Tolerance to ASA Is Verified

Pérez-Alzate D, Cornejo-García JA, Pérez-Sánchez N, Andreu I, García-Moral A, et al. Journal of investigational allergology & clinical immunology 2017;27(1):32-39

In Vitro Diagnostic Testing for Antibiotic Allergy

Doña I, Torres MJ, Montañez MI, Fernández TD Allergy, asthma & immunology research 2017 Jul;9(4):288-298

LPS promotes Th2 dependent sensitisation leading to anaphylaxis in a Pru p 3 mouse model

Rodriguez MJ, Aranda A, Fernandez TD, Cubells-Baeza N, Torres MJ, et al. Scientific reports 2017 Jan 13;7():40449

Multi-morbidities of allergic rhinitis in adults: European Academy of Allergy and Clinical Immunology Task Force Report

Cingi C, Gevaert P, Mösges R, Rondon C, Hox V, et al. Clinical and translational allergy 2017;7():17

Natural evolution in patients with nonsteroidal anti-inflammatory drug-induced urticaria/angioedema

Doña I, Barrionuevo E, Salas M, Cornejo-García JA, Perkins JR, et al. Allergy 2017 Sep;72(9):1346-1355

New developments in work-related asthma

Quirce S, Campo P, Domínguez-Ortega J, Fernández-Nieto M, Gómez-Torrijos E, et al. Expert review of clinical immunology 2017 Mar;13(3):271-281

Nonallergic rhinitis and lower airway disease

Rondón C, Bogas G, Barrionuevo E, Blanca M, Torres MJ, et al. Allergy 2017 Jan;72(1):24-34

Non-allergic rhinitis: Position paper of the European Academy of Allergy and Clinical Immunology

Hellings PW, Klimek L, Cingi C, Agache I, Akdis C, et al. Allergy 2017 Nov;72(11):1657-1665

Patients Taking Amoxicillin-Clavulanic Can Become Simultaneously Sensitized to Both Drugs

Salas M, Laguna JJ, Doña I, Barrionuevo E, Fernandez-Santamaría R, et al. The journal of allergy and clinical immunology. In practice 2017 May – Jun;5(3):694-702.e3

Pru p 3-Epitope-based sublingual immunotherapy in a murine model for the treatment of peach allergy

Rodriguez MJ, Mascaraque A, Ramos-Soriano J, Torres MJ, Perkins JR, et al. Molecular nutrition & food research 2017 Oct;61(10):

Rationale and design of the multiethnic Pharmacogenomics in Childhood Asthma consortium

Farzan N, Vijverberg SJ, Andiappan AK, Arianto L, Berce V, et al. Pharmacogenomics 2017 Jul;18(10):931-943

Response to Ebo et al., Letter to the Editor Regarding Update on Quinolone Allergy

Doña I, Moreno E, Pérez-Sánchez N, Andreu I, Fernandez de Rojas DH, et al. Current allergy and asthma reports 2017 Oct 4;17(10):75

The clinical and immunological effects of Pru p 3 sublingual immunotherapy on peach and peanut allergy in patients with systemic reactions

Gomez F, Bogas G, Gonzalez M, Campo P, Salas M, et al. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2017 Mar;47(3):339-350

The Value of In Vitro Tests to DiminishDrug Challenges

Mayorga C, Doña I, Perez-Inestrosa E, Fernández TD, Torres MJ International journal of molecular sciences 2017 Jun 7;18(6):

Update on Quinolone Allergy

Doña I, Moreno E, Pérez-Sánchez N, Andreu I, Hernández Fernandez de Rojas D, et al. Current allergy and asthma reports 2017 Aug;17(8):56

Update on the Genetic Basis of Drug Hypersensitivity Reactions.

Jurado-Escobar R, Perkins JR, García-Martín E, Isidoro-García M, Doña I, et al. Journal of investigational allergology & clinical immunology 2017;27(6):336-345

Weighted Epistatic Analysis of NSAIDs Hypersensitivity Data

Upton, A; Blanca, M; Cornejo-Garcia, JA; Perkins, JR ENGINEERING APPLICATIONS OF ARTIFICIAL INTELLIGENCE 2017

A Nonsynonymous FCER1B SNP is Associated with Risk of Developing Allergic Rhinitis and with IgE Levels

Amo G, García-Menaya J, Campo P, Cordobés C, Plaza Serón MC, et al. Scientific reports 2016 Jan 21;6():19724

A non-synonymous polymorphism in galectin-3 lectin domain is associated with allergic reactions to beta-lactam antibiotics

Cornejo-García JA, Romano A, Guéant-Rodríguez RM, Oussalah A, Blanca-López N, et al. The pharmacogenomics journal 2016 Feb;16(1):79-82

Allergic Reactions to Metamizole: Immediate and Delayed Responses

Blanca-López N, Pérez-Sánchez N, Agúndez JA, García-Martin E, Torres MJ, et al. International archives of allergy and immunology 2016;169(4):223-30

Asthma and Rhinitis Induced by Selective Immediate Reactions to Paracetamol and Non-steroidal Anti-inflammatory Drugs in Aspirin Tolerant Subjects

Pérez-Alzate D, Blanca-López N, Doña I, Agúndez JA, García-Martín E, et al. Frontiers in pharmacology 2016;7():215

Cellular Tests for the Evaluation of Drug Hypersensitivity.

Ariza A, Montanez MI, Fernandez TD, Perkins JR, Mayorga C Current pharmaceutical design 2016;22(45):6773-6783

Characterisation of non-coding genetic variation in histamine receptors using AnNCR-SNP

Rojano E, Ranea JA, Perkins JR Amino acids 2016 Oct;48(10):2433-42

Clinical Practice Guidelines for Diagnosis and Management of Hypersensitivity Reactions to Contrast Media

Rosado Ingelmo A, Doña Diaz I, Cabañas Moreno R, Moya Quesada MC, García-Avilés C, et al. Journal of investigational allergology & clinical immunology 2016;26(3):144-55; quiz 2 p following 155

Copy number variation in ALOX5 and PTGER1 is associated with NSAIDs-induced urticaria and/or angioedema

Plaza-Serón Mdel C, Ayuso P, Pérez-Sánchez N, Doña I, Blanca-Lopez N, et al. Pharmacogenetics and genomics 2016 Jun;26(6):280-7

Development of nanostructures in the diagnosis of drug hypersensitivity reactions

Mayorga C, Perez-Inestrosa E, Molina N, Montañez MI Current opinion in allergy and clinical immunology 2016 Aug;16(4):300-7

Drug allergy passport and other documentation for patients with drug hypersensitivity – An ENDA/EAACI Drug Allergy Interest Group Position Paper

Brockow K, Aberer W, Atanaskovic-Markovic M, Bavbek S, Bircher A, et al. Allergy 2016 Nov;71(11):1533-1539

FCERI and Histamine Metabolism Gene Variability in Selective Responders to NSAIDS

Amo G, Cornejo-García JA, García-Menaya JM, Cordobes C, Torres MJ, et al. Frontiers in pharmacology 2016;7():353

Fluorescent BAPAD Dendrimeric Antigens Are Efficiently Internalized by Human Dendritic Cells

Mesa-Antunez, P; Collado, D; Vida, Y; Najera, F; Fernandez, T; Torres, MJ; Perez-Inestrosa, E POLYMERS 2016

Genetic Variants of Thymic Stromal Lymphopoietin in Nonsteroidal Anti-Inflammatory Drug-Induced Urticaria/Angioedema

Plaza-Serón Mdel C, Blanca-López N, Pérez-Sánchez N, Doña I, Acosta-Herrera M, et al. International archives of allergy and immunology 2016;169(4):249-55

Hypersensitivity Reactions to Non-Steroidal Anti-Inflammatory Drugs.

Dona I, Salas M, Perkins JR, Barrionuevo E, Gaeta F, et al. Current pharmaceutical design 2016;22(45):6784-6802

Hypersensitivity to fluoroquinolones The expression of basophil activation markers depends on the clinical entity and the culprit fluoroquinolone

Fernández TD, Ariza A, Palomares F, Montañez MI, Salas M, et al. Medicine 2016 Jun;95(23):e3679

Immediate hypersensitivity reactions to ibuprofen and other arylpropionic acid derivatives

Blanca-López N, Pérez-Alzate D, Andreu I, Doña I, Agúndez JA, et al. Allergy 2016 Jul;71(7):1048-56

In vitro tests for drug hypersensitivity reactions: an ENDA/EAACI Drug Allergy Interest Group position paper

Oussalah A, Mayorga C, Blanca M, Barbaud A, Nakonechna A, et al. Allergy 2016 Apr;71(4):443-62

Is Microarray Analysis Really Useful and Sufficient to Diagnose Nut Allergy in the Mediterranean Area?

Goikoetxea MJ, D’Amelio C M, Martínez-Aranguren R, Gamboa P, Garcia BE, et al. Journal of investigational allergology & clinical immunology 2016;26(1):31-9

Is the ISAC 112 Microarray Useful in the Diagnosis of Pollinosis in Spain?

García BE, Martínez-Aranguren R, Bernard Alonso A, Gamboa P, Feo Brito F, et al. Journal of investigational allergology & clinical immunology 2016;26(2):92-9

Local Allergic Rhinitis

Campo P, Salas M, Blanca-López N, Rondón C Immunology and allergy clinics of North America 2016 May;36(2):321-32

Occupational hypersensitivity pneumonitis: an EAACI position paper

Quirce S, Vandenplas O, Campo P, Cruz MJ, de Blay F, et al. Allergy 2016 Jun;71(6):765-79

Pharmacogenomics of Prostaglandin and Leukotriene Receptors

Cornejo-García JA, Perkins JR, Jurado-Escobar R, García-Martín E, Agúndez JA, et al. Frontiers in pharmacology 2016;7():316

Pros and Cons of Clinical Basophil Testing (BAT)

Hoffmann HJ, Knol EF, Ferrer M, Mayorga L, Sabato V, et al. Current allergy and asthma reports 2016 Jul;16(8):56

Pyrazolones metabolites are relevant for identifying selective anaphylaxis to metamizole

Ariza A, García-Martín E, Salas M, Montañez MI, Mayorga C, et al. Scientific reports 2016 Mar 31;6():23845

Quantification of obeche wood allergen: Development of a sensitive sandwich-ELISA for occupational exposure assessment

Kespohl S, Campo P, Zahradnik E, Maryska S, Aranda-Guerrero A, et al. Journal of toxicology and environmental health. Part A 2016;79(22-23):1070-1077

Relationship between respiratory and food allergy and evaluation of preventive measures

Vega F, Panizo C, Dordal MT, González ML, Velázquez E, et al. Allergologia et immunopathologia 2016 May-Jun;44(3):263-75

Review: High-performance computing to detect epistasis in genome scale data sets

Upton A, Trelles O, Cornejo-García JA, Perkins JR Briefings in bioinformatics 2016 May;17(3):368-79

Seasonal Local Allergic Rhinitis in Areas With High Concentrations of Grass Pollen

Blanca-Lopez N, Campo P, Salas M, García Rodríguez C, Palomares F, et al. Journal of investigational allergology & clinical immunology 2016;26(2):83-91

The Genetics of Drug Hypersensitivity Reactions

Cornejo-García JA, Jurado-Escobar R, Doña I, Perkins JR, Agúndez JA, et al. Journal of investigational allergology & clinical immunology 2016;26(4):222-32, quiz next two pages

The influence of the carrier molecule on amoxicillin recognition by specific IgE in patients with immediate hypersensitivity reactions to betalactams

Ariza A, Mayorga C, Salas M, Doña I, Martín-Serrano Á, et al. Scientific reports 2016 Oct 12;6():35113

The role of IgE recognition in allergic reactions to amoxicillin and clavulanic acid

Torres MJ, Montañez MI, Ariza A, Salas M, Fernandez TD, et al. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2016 Feb;46(2):264-74

Two nonspecific lipid transfer proteins (nsLTPs) from tomato seeds are associated to severe symptoms of tomato-allergic patients

Martín-Pedraza L, González M, Gómez F, Blanca-López N, Garrido-Arandia M, et al. Molecular nutrition & food research 2016 May;60(5):1172-82

Understanding the mechanisms in accelerated drug reactions

Torres MJ, Salas M, Ariza A, Fernández TD Current opinion in allergy and clinical immunology 2016 Aug;16(4):308-14

Adverse reactions to immunotherapy are associated with different patterns of sensitization to grass allergens

Sastre J, Rodríguez F, Campo P, Laffond E, Marín A, et al. Allergy 2015 May;70(5):598-600

Association study of genetic variants in PLA2G4A, PLCG1, LAT, SYK, and TNFRS11A genes in NSAIDs-induced urticaria and/or angioedema patients

Ayuso P, Plaza-Serón Mdel C, Doña I, Blanca-López N, Campo P, et al. Pharmacogenetics and genomics 2015 Dec;25(12):618-21

Betalactam antibiotics affect human dendritic cells maturation through MAPK/NF-kB systems. Role in allergic reactions to drugs

Lopez S, Gomez E, Torres MJ, Pozo D, Fernandez TD, et al. Toxicology and applied pharmacology 2015 Nov 1;288(3):289-99

Clinical Management and Use of Health Care Resources in the Treatment of Nasal Polyposis in Spanish Allergy Centers: The POLAR Study

Rondón C, Dávila I, Navarro Pulido AM, Sánchez MC, Montoro J, et al. Journal of investigational allergology & clinical immunology 2015;25(4):276-82

Consensus Document on Allergic Conjunctivitis (DECA)

Sánchez-Hernández MC, Montero J, Rondon C, Benitez del Castillo JM, Velázquez E, et al. Journal of investigational allergology & clinical immunology 2015;25(2):94-106

Differential Plasma-cell evolution is linked with Dermatophagoides pteronyssinus immunotherapy response

Fernández TD, Gómez E, Doña I, Campo P, Rondon C, et al. Scientific reports 2015 Sep 29;5():14482

Drug hypersensitivity in clonal mast cell disorders: ENDA/EAACI position paper

Bonadonna P, Pagani M, Aberer W, Bilò MB, Brockow K, et al. Allergy 2015 Jul;70(7):755-63

Drug metabolism and hypersensitivity reactions to drugs

Agúndez JA, Mayorga C, García-Martin E Current opinion in allergy and clinical immunology 2015 Aug;15(4):277-84

Genetic basis of hypersensitivity reactions to nonsteroidal anti-inflammatory drugs

Gómez F, Perkins JR, García-Martín E, Canto G, Cornejo-García JA Current opinion in allergy and clinical immunology 2015 Aug;15(4):285-93

Genetic determinants of metamizole metabolism modify the risk of developing anaphylaxis

García-Martín E, Esguevillas G, Blanca-López N, García-Menaya J, Blanca M, et al. Pharmacogenetics and genomics 2015 Sep;25(9):462-4

Genetic variants in arachidonic acid pathway genes associated with NSAID-exacerbated respiratory disease

Ayuso P, Plaza-Serón Mdel C, Blanca-López N, Doña I, Campo P, et al. Pharmacogenomics 2015 Jul;16(8):825-39

Glycodendropeptides stimulate dendritic cell maturation and T cell proliferation: a potential influenza A virus immunotherapy

Mascaraque, A; Kowalczyk, W; Fernandez, T; Palomares, F; Mayorga, C; Andreu, D; Rojo, J MEDCHEMCOMM 2015

Highly sensitive dendrimer-based nanoplasmonic biosensor for drug allergy diagnosis

Soler M, Mesa-Antunez P, Estevez MC, Ruiz-Sanchez AJ, Otte MA, et al. Biosensors & bioelectronics 2015 Apr 15;66():115-23

HLA-DRA variants predict penicillin allergy in genome-wide fine-mapping genotyping

Guéant JL, Romano A, Cornejo-Garcia JA, Oussalah A, Chery C, et al. The Journal of allergy and clinical immunology 2015 Jan;135(1):253-9

Hypersensitivity Reactions to beta-Lactams: Relevance of Hapten-Protein Conjugates

Ariza A, Mayorga C, Fernandez TD, Barbero N, Martín-Serrano A, et al. Journal of investigational allergology & clinical immunology 2015;25(1):12-25

Hypersensitivity Reactions to Nonsteroidal Anti-inflammatory Drugs in Children and Adolescents: Selective Reactions

Blanca-López N, Cornejo-García JA, Pérez-Alzate D, Pérez-Sánchez N, Plaza-Serón MC, et al. Journal of investigational allergology & clinical immunology 2015;25(6):385-95

Hypersensitivity to Nonsteroidal Anti-inflammatory Drugs in Children and Adolescents: Cross-Intolerance Reactions

Blanca-López N, Cornejo-García JA, Plaza-Serón MC, Doña I, Torres-Jaén MJ, et al. Journal of investigational allergology & clinical immunology 2015;25(4):259-69

Immunologic responses to the major allergen of Olea europaea in local and systemic allergic rhinitis subjects

Campo P, Villalba M, Barrionuevo E, Rondón C, Salas M, et al. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2015 Nov;45(11):1703-12

Influence of age on IgE response in peanut-allergic children and adolescents from the Mediterranean area

Garcia-Blanca A, Aranda A, Blanca-Lopez N, Perez D, Gomez F, et al. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2015 Sep;26(6):497-502

Initial immunological changes as predictors for house dust mite immunotherapy response

Gómez E, Fernández TD, Doña I, Rondon C, Campo P, et al. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2015 Oct;45(10):1542-53

Intracellular accumulation and immunological properties of fluorescent gold nanoclusters in human dendritic cells

Fernández TD, Pearson JR, Leal MP, Torres MJ, Blanca M, et al. Biomaterials 2015 Mar;43():1-12

Light induced cytosolic drug delivery from liposomes with gold nanoparticles

Lajunen T, Viitala L, Kontturi LS, Laaksonen T, Liang H, et al. Journal of controlled release : official journal of the Controlled Release Society 2015 Apr 10;203():85-98

Local allergic rhinitis: mechanisms, diagnosis and relevance for occupational rhinitis

Gómez F, Rondón C, Salas M, Campo P Current opinion in allergy and clinical immunology 2015 Apr;15(2):111-6

Local IgE in non-allergic rhinitis

Campo P, Rondón C, Gould HJ, Barrionuevo E, Gevaert P, et al. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2015 May;45(5):872-881

Multivalent Glycosylation of Fluorescent Gold Nanoclusters Promotes Increased Human Dendritic Cell Targeting via Multiple Endocytic Pathways

Le Guével X, Perez Perrino M, Fernández TD, Palomares F, Torres MJ, et al. ACS applied materials & interfaces 2015 Sep 23;7(37):20945-56

Nanoparticle size influences the proliferative responses of lymphocyte subpopulations

le Guevel, X; Palomares, F; Torres, MJ; Blanca, M; Fernandez, TD; Mayorga, C RSC ADVANCES 2015

Pharmacogenomics of cyclooxygenases

Agúndez JA, Blanca M, Cornejo-García JA, García-Martín E Pharmacogenomics 2015;16(5):501-22

Phenotypes and endotypes of rhinitis and their impact on management: a PRACTALL report

Papadopoulos NG, Bernstein JA, Demoly P, Dykewicz M, Fokkens W, et al. Allergy 2015 May;70(5):474-94

Recognition of multiepitope dendrimeric antigens by human immunoglobulin E

Montañez MI, Najera F, Mayorga C, Ruiz-Sanchez AJ, Vida Y, et al. Nanomedicine : nanotechnology, biology, and medicine 2015 Apr;11(3):579-88

Selective immediate responders to amoxicillin and clavulanic acid tolerate penicillin derivative administration after confirming the diagnosis

Blanca-Lopez N, Perez-Alzate D, Ruano F, Garcimartin M, de la Torre V, et al. Allergy 2015 Aug;70(8):1013-9

The clinical utility of basophil activation testing in diagnosis and monitoring of allergic disease

Hoffmann HJ, Santos AF, Mayorga C, Nopp A, Eberlein B, et al. Allergy 2015 Nov;70(11):1393-405

Unravelling adverse reactions to NSAIDs using systems biology

Perkins JR, Sanak M, Canto G, Blanca M, Cornejo-García JA Trends in pharmacological sciences 2015 Mar;36(3):172-80


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