Investigación Clínica en Infección VIH, Infección Endovascular y Bacteriemias

Lineas de Investigación

01. Infección por el VIH.

02. Otras infecciones de transmisión sexual.

03. Infecciones endovascular y bacteriemias

04. Infecciones osteoarticulares.



Estudios Clínicos

Temocilina vs Meropenem para el Tratamiento de la Bacteriemia por Enterobacteriales Resistentes a Cefalosporinas de Tercera Generación: Ensayo Aleatorizado y Pragmático..

FUNDACION PUBLICA ANDALUZA PARA LA GESTION DE LA INVESTIGACIÓN EN SALUD DE SEVILLA FISEVI
Fase: III Ensayo Clínico Comercial

CDC-Ensayo clínico fase I/II multicéntrico, aleatorizado y controlado para evaluar la eficacia del tratamiento con plasma hiperinmune obtenido de donantes convalecientes de la infección por COVID-19.

FUNDACION PUBLICA ANDALUZA PROGRESO Y SALUD
Fase: I Ensayo Clínico Comercial

“CDC-PREVENCION DE ENFERMEDAD POR SARS-CoV-2 (COVID-19) MEDIANTE LA PROFILAXIS PRE-EXPOSICIÓN DE EMTRICITABINA/TENOFOVIR DISOPROXILO E HIDROXICLOROQUINA EN PERSONAL SANITARIO: ENSAYO CLÍNICO ALEATORIZADO, CONTROLADO CON PLACEBO”.

Plan Nacional Sobre Sida
Fase: III Ensayo Clínico Comercial

CDC-Un ensayo aleatorizado internacional para evaluar tratamientos no licenciados para COVID-19 en pacientes hospitalizados que reciben el tratamiento convencional para COVID que se ofrece en cada hospital. SOLIDARITY.

FUNDACION PARA LA INVESTIGACION BIOMEDICA DEL HOSPITAL CLINICO SAN CARLOS INSTITUTO DE INVESTIGACION SANITARIA SAN CARLOS
Fase: III Ensayo Clínico Comercial

Estudio clínico de fase 3, aleatorizado, doble ciego y comparativo con tratamiento activo para evaluar la actividad antirretroviral, la seguridad y la tolerabilidad de doravirina/islatravir una vez al día en participantes infectados por el VIH-1 sin tra.

MERCK SHARP & DOHME DE ESPAÑA SA
Fase: III Ensayo Clínico Comercial

Estudio clínico de fase 3, aleatorizado, doble ciego y controlado con producto activo para evaluar el cambio a doravirina/islatravir (DOR/ISL) una vez al día en participantes con supresión virológica del VIH-1 con bictegravir/emtricitabina/tenofovir a.

MERCK SHARP & DOHME DE ESPAÑA SA
Fase: III Ensayo Clínico Comercial

201636. Estudio Fase III aleatorizado, multicéntrico, de grupos paralelos, de no inferioridad, para evaluar la eficacia, seguridad y tolerabilidad del cambio de una terapia antirretroviral basada en INI, ITINN o IP a dolutegravir más rilpivirina en pacientes adul

LABORATORIOS VIIV HEALTHCARE S.L.
Fase: III ENSAYO CLINICO COMERCIAL

SYMTRI. SYMTRI Study: Ensayo clínico abierto, aleatorizado y multicéntrico para comparar la eficacia, seguridad y tolerabilidad de una pauta de tratamiento TAF/FTC/DRV/cobi vs. ABC/3TC/DTG en pacientes infectados por el VIH-1 naïve de tratamiento antirretroviral.

RED DE INVESTIGACIÓN EN SIDA
Fase: IV ENSAYO CLINICO INDEPENDIENTE

GS-US-311-1717.

Estudio de fase 3b, aleatorizado, doble ciego, con cambio de tratamiento para evaluar F/TAF, en pacientes con infección por VIH-1 y supresión virológica que reciben tratamientos que contienen ABC/3TC

GILEAD SCIENCES, INC
Fase: IIIb ENSAYO CLINICO COMERCIAL

GS-US-380-1878.

Estudio fase III, aleatorizado y abierto para evaluar la seguridad y eficacia del cambio de un régimen formado por atazanavir o darunavir reforzados más emtricitabina/tenofovir o abacavir/lamivudina a GS 9883/emtricitabina/tenofovir alafenamida en adultos

GILEAD SCIENCES, INC
Fase: III ENSAYO CLINICO COMERCIAL

GS-US-380-1490.

Estudio de fase 3, aleatorizado y doble ciego para evaluar la seguridad y la eficacia de GS-9883/emtricitabina/tenofovir alefenamida en comparación con dolutegravir + emtricitabina/tenofovir alefenamida en adultos infectados por el VIH-1 sin tratamiento a

GILEAD SCIENCES, INC
Fase: III ENSAYO CLINICO COMERCIAL

204862. Estudio de fase III, aleatorizado, multicéntrico, con grupos paralelos y de ausencia de inferioridad para evaluar la eficacia, la seguridad y la tolerabilidad del cambio a dolutegravir más lamivudina en adultos infectados por el VIH 1 con supresión viroló

VIIV HEALTHCARE UK LIMITED
Fase: III ENSAYO CLINICO COMERCIAL

Publicaciones científicas

  • Todo
  • D1
  • Q1
  • Q2
  • Otro
A Genome-Wide Association Study on Liver Stiffness Changes during Hepatitis C Virus Infection Cure

Corma-Gómez A, Macías J, Rivero A, Rivero-Juarez A, de Los Santos I, et al. Diagnostics (Basel, Switzerland) 2021 Aug 20;11(8):

A Pandemic within Other Pandemics. When a Multiple Infection of a Host Occurs: SARS-CoV-2, HIV and Mycobacterium tuberculosis

González-Domenech CM, Pérez-Hernández I, Gómez-Ayerbe C, Viciana Ramos I, Palacios-Muñoz R, et al. Viruses 2021 May 17;13(5):

Acute hepatitis C virus infection and direct-acting antiviral drugs: Perfect combination to eliminate the epidemic?

Gomez-Ayerbe, C; Palacios, R; Rios, MJ; Tellez, F; Sayago, C; Martin-Aspas, A; Camacho, A; Munoz, L; Santos, J INTERNATIONAL JOURNAL OF STD & AIDS 2021

Analysis of sex differences in the clinical presentation, management and prognosis of infective endocarditis in Spain

Barca, LV; Vidal-Bonnet, L; Farinas, MC; Munoz, P; Minero, MV; de Alarcon, A; Carretero, EG; Cuadra, MG; Camacho, AM; Urkola, XK; Agirre, JG; Burgos, GO; Lopez-Cortes, LE; Azpiroz, JCP; Lopez-Menendez, J HEART 2021

Blood culture-negative infective endocarditis: a worse outcome? Results from a large multicentre retrospective Spanish cohort study

Suardi, LR; de Alarcon, A; Garcia, MV; Ciezar, AP; Tenorio, CH; Martinez-Marcos, FJ; Concejo-Martinez, E; Lima, JD; Garcia, DV; Marquez, RL; Ojeda, G; Iglesias, JMR; Lomas, JM; Lopez-Cortes, LE INFECTIOUS DISEASES 2021

Clinical Factors Associated with Reinfection versus Relapse in Infective Endocarditis: Prospective Cohort Study

Calderón-Parra J, Kestler M, Ramos-Martínez A, Bouza E, Valerio M, et al. Journal of clinical medicine 2021 Feb 13;10(4):

Cryptococcal infection in HIV-infected patients with CD4(+) T-cell counts under 100/mu L diagnosed in a high-income country: a multicentre cohort study

Asin, MAPJ; Bisbal, O; Iribarren, JA; Perez-Rivilla, A; Mican, R; Dronda, F; Gonzalez-Domenech, CM; Vinuesa-Garcia, D; Macias, J; Lumbreras, C; Moreno, S; Rubio, R CLINICAL MICROBIOLOGY AND INFECTION 2021

Do specific antimicrobial stewardship interventions have an impact on carbapenem resistance in Gram-negative bacilli? A multicentre quasi-experimental ecological study: time-trend analysis and characterization of carbapenemases

Alvarez-Marin, R; Lopez-Cerero, L; Guerrero-Sanchez, F; Palop-Borras, B; Rojo-Martin, MD; Ruiz-Sancho, A; Herrero-Rodriguez, C; Garcia, MV; Lazo-Torres, AM; Lopez, I; Martin-Hita, L; Nuno-Alvarez, E; Sanchez-Yebra, W; Galan-Sanchez, F; Reguera-Iglesias, JM; Lepe, JA; Penalva, G; Pascual, A; Cisneros, JM JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 2021

Dynamics of creatinine estimated glomerular filtration rate using one or more antiretrovirals that inhibit creatinine tubular secretion

Elias, MJP; Alejos, B; Gutierrez, MM; Crespo, M; Gil, ID; Ribera, E; Galindo, MJ; Lozano, F; Cifre, AP; Boix, V; Montero-Alonso, M; Sanz, J; Lima, JD; Palacios, R; Moral, SDF; Martinez, E JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 2021

Failure on voxilaprevir, velpatasvir, sofosbuvir and efficacy of rescue therapy

Dietz, J; Di Maio, VC; de Salazar, A; Merino, D; Vermehren, J; Paolucci, S; Kremer, AE; Lara, M; Pardo, MR; Zoller, H; Degasperi, E; Peiffer, KH; Sighinolfi, L; Tellez, F; Graf, C; Ghisetti, V; Schreiber, J; Fernandez-Fuertes, E; Boglione, L; Munoz-Medina, L; Stauber, R; Gennari, W; Figueruela, B; Santos, J; Lampertico, P; Zeuzem, S; Ceccherini-Silberstein, F; Garcia, F; Sarrazin, C JOURNAL OF HEPATOLOGY 2021

Hepatitis C and HIV combined screening in primary care: A cluster randomized trial

Martinez-Sanz, J; Vivancos, MJ; Sanchez-Conde, M; Gomez-Ayerbe, C; Polo, L; Labrador, C; Gonzalez, P; Mesa, A; Muriel, A; Chamorro, C; de la Fuente, Y; Elias, PP; Uranga, A; Herrero, M; Ares, S; Barea, R; Moreno, S; Perez-Elias, MJ JOURNAL OF VIRAL HEPATITIS 2021

Human Immunodeficiency Virus (HIV) Infection Is Associated With Lower Risk of Hepatocellular Carcinoma After Sustained Virological Response to Direct-acting Antivirals in Hepatitis C Infected Patients With Advanced Fibrosis

Corma-Gomez, A; Macias, J; Lacalle-Remigio, JR; Tellez, F; Morano, L; Rivero, A; Serrano, M; Rios, MJ; Vera-Mendez, FJ; Alados, JC; Real, LM; Palacios, R; De los Santos, I; Imatz, A; Pineda, JA CLINICAL INFECTIOUS DISEASES 2021

Incidence of recently acquired hepatitis C virus infection among HIV-infected patients in southern Spain

Gonzalez-Serna, A; Macias, J; Palacios, R; Gomez-Ayerbe, C; Tellez, F; Rivero-Juarez, A; Fernandez, M; Santos, J; Real, LM; Gonzalez-Domenech, CM; Gomez-Mateos, J; Pineda, JA HIV MEDICINE 2021

Liver Stiffness-Based Strategies Predict Absence of Variceal Bleeding in Cirrhotic Hepatitis C Virus-Infected Patients With and Without Human Immunodeficiency Virus Coinfection After Sustained Virological Response

Corma-Gomez, A; Macias, J; Morano, L; Rivero, A; Tellez, F; Rios, MJ; Santos, M; Serrano, M; Palacios, R; Merino, D; Real, LM; De Los Santos, I; Vera-Mendez, FJ; Galindo, MJ; Pineda, JA CLINICAL INFECTIOUS DISEASES 2021

Prevalence of Colorectal Neoplasms Among Patients With Enterococcus faecalis Endocarditis in the GAMES Cohort (2008-2017)

Pericas, JM; Ambrosioni, J; Munoz, P; de Alarcon, A; Kestler, M; Mari-Hualde, A; Moreno, A; Goenaga, MA; Farinas, MC; Rodriguez-Alvarez, R; Ojeda-Burgos, G; Galvez-Acebal, J; Hidalgo-Tenorio, C; Noureddine, M; Miro, JM MAYO CLINIC PROCEEDINGS 2021

Tumour form of neurocysticercosis in a patient with prostate carcinoma

Carazo-Barrios, L; Delgado-Gil, V; Leon-Plaza, O; Gomez-Ayerbe, C REVISTA DE NEUROLOGIA 2021

A Contemporary Picture of Enterococcal Endocarditis

Pericàs JM, Llopis J, Muñoz P, Gálvez-Acebal J, Kestler M, et al. Journal of the American College of Cardiology 2020 Feb 11;75(5):482-494

Clinical and prognostic differences between methicillin-resistant and methicillin-susceptible Staphylococcus aureus infective endocarditis

Hidalgo-Tenorio C, Gálvez J, Martínez-Marcos FJ, Plata-Ciezar A, De La Torre-Lima J, et al. BMC infectious diseases 2020 Feb 21;20(1):160

Factors associated with the number of drugs in darunavir/cobicistat regimens

Martinez E, Negredo E, Knobel H, Ocampo A, Sanz J, et al. The Journal of antimicrobial chemotherapy 2020 Jan 1;75(1):208-214

Four weeks versus six weeks of ampicillin plus ceftriaxone in Enterococcus faecalis native valve endocarditis: A prospective cohort study

Ramos-Martínez A, Pericàs JM, Fernández-Cruz A, Muñoz P, Valerio M, et al. PloS one 2020;15(8):e0237011

GEHEP 010 study: Prevalence and distribution of hepatitis B virus genotypes in Spain (2000-2016)

Aguilera A, Trastoy R, Rodríguez-Frias F, Muñoz-Bellido JL, Melón S, et al. The Journal of infection 2020 Oct;81(4):600-606

Genetic variants in the LPL and GPIHBP1 genes, in patients with severe hypertriglyceridaemia, detected with high resolution melting analysis

Ariza MJ, Pérez-López C, Almagro F, Sánchez-Tévar AM, Muñiz-Grijalvo O, et al. Clinica chimica acta; international journal of clinical chemistry 2020 Jan;500():163-171

High Prevalence of Sequences Included in Transmission Clusters Within Newly Diagnosed HIV-1 Patients in Southern Spain (2004-2015)

González-Domenech CM, Sena-Corrales G, Viciana-Ramos I, Palacios-Muñoz R, Mora-Navas L, et al. Microbial drug resistance (Larchmont, N.Y.) 2020 Sep;26(9):1090-1097

Impact of HIV on the survival of hepatocellular carcinoma in hepatitis C virus-infected patients

Merchante N, Rodríguez-Fernández M, Figueruela B, Rodríguez-Arrondo F, Revollo B, et al. AIDS (London, England) 2020 Aug 1;34(10):1497-1507

Liver Stiffness at the Time of Sustained Virological Response Predicts the Clinical Outcome in People Living With Human Immunodeficiency Virus and Hepatitis C Virus With Advanced Fibrosis Treated With Direct-acting Antivirals

Corma-Gómez A, Macías J, Téllez F, Freyre-Carrillo C, Morano L, et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2020 Dec 3;71(9):2354-2362

Maintenance of virologic suppression and improvement in comorbidities after simplification to raltegravir plus boosted darunavir among treatment-experienced HIV-infected patients

Casado JL, Vizcarra P, Blanco JL, Montejano R, Negredo E, et al. International journal of STD & AIDS 2020 Apr;31(5):467-473

Prognostic assessment of valvular surgery in active infective endocarditis: multicentric nationwide validation of a new score developed from a meta-analysis

Varela Barca L, Fernández-Felix BM, Navas Elorza E, Mestres CA, Muñoz P, et al. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2020 Apr 1;57(4):724-731

Quasiexperimental intervention study protocol to optimise the use of new antibiotics in Spain: the NEW_SAFE project

Palacios-Baena ZR, Valiente de Santis L, Maldonado N, Rosso-Fernández CM, Borreguero I, et al. BMJ open 2020 Jul 31;10(7):e035460

Risk of cardiovascular disease in patients with HIV infection undergoing antiretroviral therapy

Estrada V, Domingo P, Suarez-Lozano I, Gutiérrez F, Knobel H, et al. Revista clinica espanola 2020 Apr;220(3):149-154

Towards the elimination of hepatitis C: implementation of reflex testing in Andalusia

Casas MP, García F, Freyre-Carrillo C, Montiel N, de la Iglesia A, et al. Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 2020 Jul;112(7):515-519

Using machine learning methods to determine a typology of patients with HIV-HCV infection to be treated with antivirals

Rivero-Juárez A, Guijo-Rubio D, Tellez F, Palacios R, Merino D, et al. PloS one 2020;15(1):e0227188

What is needed to achieve HCV microelimination among HIV-infected populations in Andalusia, Spain: a modeling analysis

Skaathun B, Borquez A, Rivero-Juarez A, Mehta SR, Tellez F, et al. BMC infectious diseases 2020 Aug 8;20(1):588

A genome-wide association study on low susceptibility to hepatitis C virus infection (GEHEP012 study)

Real LM, Fernández-Fuertes M, Sáez ME, Rivero-Juárez A, Frías M, et al. Liver international : official journal of the International Association for the Study of the Liver 2019 Oct;39(10):1918-1926

Analysis of the costs and cost-effectiveness of the guidelines recommended by the 2018 GESIDA/Spanish National AIDS Plan for initial antiretroviral therapy in HIV-infected adults

Pérez-Molina JA, Martínez E, Blasco AJ, Arribas JR, Domingo P, et al. Enfermedades infecciosas y microbiologia clinica (English ed.) 2019 Mar;37(3):151-159

Durability of first-line antiretroviral regimens in the era of integrase inhibitors: a cohort of HIV-positive individuals in Spain, 2014-2015.

Jarrin I, Suarez-Garcia I, Moreno C, Tasias M, Del Romero J, et al. Antiviral therapy 2019;24(3):167-175

Early emergence of opportunistic infections after starting direct-acting antiviral drugs in HIV/HCV-coinfected patients

Macías J, Téllez F, Rivero-Juárez A, Palacios R, Morano LE, et al. Journal of viral hepatitis 2019 Jan;26(1):48-54

Evaluation of hepatitis C viral RNA persistence in HIV-infected patients with long-term sustained virological response by droplet digital PCR

Frías M, Rivero-Juárez A, Téllez F, Palacios R, Jiménez-Arranz Á, et al. Scientific reports 2019 Aug 29;9(1):12507

Executive summary of the consensus document on metabolic disorders and cardiovascular risk in patients with HIV infection

Panel of Experts from the Metabolic Disorders and Comorbilities Study Group (GEAM)., Aids Study Group (GeSIDA)., National Aids Plan (PNS). Electronic address: rpolor@msssi.es. Enfermedades infecciosas y microbiologia clinica (English ed.) 2019 Jan;37(1):50-55

Executive summary of the GeSIDA consensus document on control and monitoring of HIV-infected patients

AIDS Study Group (GeSIDA) of the Spanish Society of Infectious Diseases and Clinical Microbiology., AIDS Study Group (GeSIDA) of the Spanish Society of Infectious Diseases and Clinical Microbiology. Enfermedades infecciosas y microbiologia clinica (English ed.) 2019 Aug – Sep;37(7):467-475

Executive summary of the GeSIDA/National AIDS Plan consensus document on antiretroviral therapy in adults infected by the human immunodeficiency virus (updated January 2018)

AIDS Study Group (GeSIDA) of the Spanish Society of Infectious Diseases and Clinical Microbiology and the National AIDS Plan:., AIDS Study Group (GeSIDA) of the Spanish Society of Infectious Diseases and Clinical Microbiology and the National AIDS Plan:. Enfermedades infecciosas y microbiologia clinica (English ed.) 2019 Mar;37(3):195-202

Fractional excretion of phosphorus and vascular calcification in stage 3 chronic kidney disease

Jiménez Villodres M, García Gutiérrez G, García Frías P, Rioja Villodres J, Martín Velázquez M, et al. Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2019 Mar;67(3):674-680

Higher relapse rate among HIV/HCV-coinfected patients receiving sofosbuvir/ledipasvir for 8 vs 12 weeks

Corma-Gómez A, Macías J, Merino Muñoz D, Téllez F, Granados R, et al. The Journal of infection 2019 Jul;79(1):30-35

IL7RA rs6897932 Polymorphism Is Associated with Better CD4(+) T-Cell Recovery in HIV Infected Patients Starting Combination Antiretroviral Therapy

Resino S, Navarrete-Muñoz MA, Blanco J, Pacheco YM, Castro I, et al. Biomolecules 2019 Jun 16;9(6):

Incidence of lymphoma in HIV-HCV-infected patients. Modifications in function of the anti-hepatitis C virus therapy

Gutiérrez-Saborido D, Gutiérrez-Valencia A, González Domenech CM, López Ruz MÁ, Raffo Márquez M, et al. Annals of hematology 2019 Aug;98(8):1953-1959

Left-sided infective endocarditis caused by Streptococcus agalactiae: rare and serious

Ivanova-Georgieva R, Ruiz-Morales J, García-Cabrera E, García-López MV, Gálvez-Acebal J, et al. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2019 Feb;38(2):265-275

Low performance of ultrasound surveillance for the diagnosis of hepatocellular carcinoma in HIV-infected patients

Merchante N, Figueruela B, Rodríguez-Fernández M, Rodríguez-Arrondo F, Revollo B, et al. AIDS (London, England) 2019 Feb 1;33(2):269-278

OXA-48-Like-Producing Klebsiella pneumoniae in Southern Spain in 2014-2015

Machuca J, López-Cerero L, Fernández-Cuenca F, Mora-Navas L, Mediavilla-Gradolph C, et al. Antimicrobial agents and chemotherapy 2019 Jan;63(1):

Parenteral drug use as the main barrier to hepatitis C treatment uptake in HIV-infected patients

Rivero-Juarez A, Tellez F, Castaño-Carracedo M, Merino D, Espinosa N, et al. HIV medicine 2019 Jul;20(6):359-367

Predictive factors of renal impairment in HIV-infected patients on antiretroviral therapy: Results from the VACH longitudinal cohort study

Domingo P, Suarez-Lozano I, Gutierrez F, Estrada V, Knobel H, et al. Nefrologia 2019 Sep – Oct;39(5):497-505

Rate of cardiovascular, renal and bone disease and their major risks factors in HIV-infected individuals on antiretroviral therapy in Spain

Knobel H, Domingo P, Suarez-Lozano I, Gutierrez F, Estrada V, et al. Enfermedades infecciosas y microbiologia clinica (English ed.) 2019 Jun – Jul;37(6):373-379

Reliable resolution of ambiguous hepatitis C virus genotype 1 results with the Abbott HCV Genotype Plus RUO assay

Saludes V, Antuori A, Reinhardt B, Viciana I, Clavijo E, et al. Scientific reports 2019 Mar 6;9(1):3678

Response to direct-acting antiviral therapy among ongoing drug users and people receiving opioid substitution therapy

Macías J, Morano LE, Téllez F, Granados R, Rivero-Juárez A, et al. Journal of hepatology 2019 Jul;71(1):45-51

Role of age and comorbidities in mortality of patients with infective endocarditis

Armiñanzas C, Fariñas-Alvarez C, Zarauza J, Muñoz P, González Ramallo V, et al. European journal of internal medicine 2019 Jun;64():63-71

Similar recovery of liver function after response to all-oral HCV therapy in patients with cirrhosis with and without HIV coinfection

Macías J, Granados R, Téllez F, Merino D, Pérez M, et al. Journal of viral hepatitis 2019 Jan;26(1):16-24

Surveillance of transmitted drug resistance to integrase inhibitors in Spain: implications for clinical practice

Alvarez M, Casas P, de Salazar A, Chueca N, Guerrero-Beltran C, et al. The Journal of antimicrobial chemotherapy 2019 Jun 1;74(6):1693-1700

Validation of a basic neurosonology laboratory for detecting cervical carotid artery stenosis

de la Cruz Cosme C, Dawid Milner MS, Ojeda Burgos G, Gallardo Tur A, Márquez Martínez M, et al. Neurologia (Barcelona, Spain) 2019 Jul – Aug;34(6):367-375

Class-modeling analysis reveals T-cell homeostasis disturbances involved in loss of immune control in elite controllers

Benito JM, Ortiz MC, León A, Sarabia LA, Ligos JM, et al. BMC medicine 2018 Feb 28;16(1):30

Consensus document on the diagnosis and treatment of sexually transmitted diseases in adults, children and adolescents

AIDS Study Group (GESIDA)., National Aids Plan, STI Study group of the SEIMC (GEITS)., Spanish Group for the Investigation of Sexual Transmission Diseases of the Spanish Academy of Dermatology and Venerology., Spanish Society for Pediatric Infectious (SEIP). Enfermedades infecciosas y microbiologia clinica (English ed.) 2018 Nov;36(9):576-585

Continued propagation of the CRF19_cpx variant among HIV-positive MSM patients in Spain

Pérez-Parra S, Álvarez M, Fernandez-Caballero JA, Pérez AB, Santos J, et al. The Journal of antimicrobial chemotherapy 2018 Apr 1;73(4):1031-1038

Costs and cost-efficacy analysis of the 2017 GESIDA/Spanish National AIDS Plan recommended guidelines for initial antiretroviral therapy in HIV-infected adults

Rivero A, Pérez-Molina JA, Blasco AJ, Arribas JR, Asensi V, et al. Enfermedades infecciosas y microbiologia clinica (English ed.) 2018 May;36(5):268-276

Emergence as an outbreak of the HIV-1 CRF19_cpx variant in treatment-naive patients in southern Spain

González-Domenech CM, Viciana I, Delaye L, Mayorga ML, Palacios R, et al. PloS one 2018;13(1):e0190544

Executive summary of the GESIDA/National AIDS Plan Consensus Document on Antiretroviral Therapy in Adults Infected by the Human Immunodeficiency Virus (Updated January 2017)

AIDS Study Group (GESIDA) of the Spanish Society of Infectious Diseases and Clinical Microbiology and the National AIDS Plan., AIDS Study Group (GESIDA) of the Spanish Society of Infectious Diseases and Clinical Microbiology and the National AIDS Plan. Enfermedades infecciosas y microbiologia clinica (English ed.) 2018 Aug – Sep;36(7):435-445

Gentamicin may have no effect on mortality of staphylococcal prosthetic valve endocarditis

Ramos-Martínez A, Muñoz Serrano A, de Alarcón González A, Muñoz P, Fernández-Cruz A, et al. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2018 Jul;24(7):555-562

Human Immunodeficiency Virus/Hepatits C Virus Coinfection in Spain: Elimination Is Feasible, but the Burden of Residual Cirrhosis Will Be Significant

Berenguer J, Jarrín I, Pérez-Latorre L, Hontañón V, Vivancos MJ, et al. Open forum infectious diseases 2018 Jan;5(1):ofx258

Impact of Staphylococcus aureus phenotype and genotype on the clinical characteristics and outcome of infective endocarditis. A multicentre, longitudinal, prospective, observational study

Fernández-Hidalgo N, Ribera A, Larrosa MN, Viedma E, Origüen J, et al. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2018 Sep;24(9):985-991

Lipid changes and tolerability in a cohort of adult HIV-infected patients who switched to rilpivirine/emtricitabine/tenofovir due to intolerance to previous combination ART: the PRO-STR study

Ocampo A, Domingo P, Fernández P, Diz J, Barberá JR, et al. The Journal of antimicrobial chemotherapy 2018 Aug 1;73(8):2171-2176

Paritaprevir/ritonavir/ombitasvir plus dasabuvir in HIV/HCV-coinfected patients with genotype 1 in real-life practice

Pineda JA, Rivero-Juárez A, de Los Santos I, Collado A, Merino D, et al. HIV clinical trials 2018 Feb;19(1):23-30

Role of APOBEC3H in the Viral Control of HIV Elite Controller Patients

Benito JM, Hillung J, Restrepo C, Cuevas JM, León A, et al. International journal of medical sciences 2018;15(2):95-100

Sustained virological response to direct-acting antiviral regimens reduces the risk of hepatocellular carcinoma in HIV/HCV-coinfected patients with cirrhosis

Merchante N, Rivero-Juárez A, Téllez F, Merino D, Ríos-Villegas MJ, et al. The Journal of antimicrobial chemotherapy 2018 Sep 1;73(9):2435-2443

Symtuza (DRV/c/FTC/TAF) in the management of treatment-naive HIV-patients.

Gómez Ayerbe C, Santos González J, Palacios Muñoz R Enfermedades infecciosas y microbiologia clinica (English ed.) 2018 Dec;36 Suppl 2():17-21

The Kidney, Liver, Index surgery and C reactive protein score is a predictor of treatment response in acute prosthetic joint infection

Jiménez-Garrido C, Gómez-Palomo JM, Rodríguez-Delourme I, Durán-Garrido FJ, Nuño-Álvarez E, et al. International orthopaedics 2018 Jan;42(1):33-38

Aetiology of renal failure in patients with infective endocarditis. The role of antibiotics

Goenaga Sánchez MÁ, Kortajarena Urkola X, Bouza Santiago E, Muñoz García P, Verde Moreno E, et al. Medicina clinica 2017 Oct 23;149(8):331-338

Costs and cost-efficacy analysis of the 2016 GESIDA/Spanish AIDS National Plan recommended guidelines for initial antiretroviral therapy in HIV-infected adults

Rivero A, Pérez-Molina JA, Blasco AJ, Arribas JR, Crespo M, et al. Enfermedades infecciosas y microbiologia clinica 2017 Feb;35(2):88-99

Endocarditis caused by anaerobic bacteria

Kestler M, Muñoz P, Marín M, Goenaga MA, Idígoras Viedma P, et al. Anaerobe 2017 Oct;47():33-38

Hepatic safety of maraviroc in HIV-1-infected patients with hepatitis C and/or B co-infection. The Maraviroc Cohort Spanish Group

Crespo M, Navarro J, Moreno S, Sanz J, Márquez M, et al. Enfermedades infecciosas y microbiologia clinica 2017 Oct;35(8):493-498

Hepatitis C virus core antigen in the management of patients treated with new direct-acting antivirals

Arboledas JCA, Guerrero IP, Rodríguez MJB, Martos ET, Pérez AB, et al. Diagnostic microbiology and infectious disease 2017 Sep;89(1):29-34

Impact of universal access to hepatitis C therapy on HIV-infected patients: implementation of the Spanish national hepatitis C strategy

Rivero-Juarez A, Lopez-Cortes LF, Castaño M, Merino D, Marquez M, et al. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2017 Mar;36(3):487-494

Infective endocarditis in patients with bicuspid aortic valve: Clinical characteristics, complications, and prognosis

Becerra-Muñoz VM, Ruíz-Morales J, Rodríguez-Bailón I, Sánchez-Espín G, López-Garrido MA, et al. Enfermedades infecciosas y microbiologia clinica 2017 Dec;35(10):645-650

Liver stiffness predicts the response to direct-acting antiviral-based therapy against chronic hepatitis C in cirrhotic patients

Neukam K, Morano-Amado LE, Rivero-Juárez A, Macías J, Granados R, et al. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2017 May;36(5):853-861

Liver stiffness predicts variceal bleeding in HIV/HCV-coinfected patients with compensated cirrhosis

Merchante N, Rivero-Juárez A, Téllez F, Merino D, Ríos-Villegas MJ, et al. AIDS (London, England) 2017 Feb 20;31(4):493-500

Prevalence and distribution of hepatitis C virus genotypes in Spain during the 2000-2015 period (the GEHEP 005 study)

Aguilera A, Navarro D, Rodríguez-Frias F, Viciana I, Martínez-Sapiña AM, et al. Journal of viral hepatitis 2017 Sep;24(9):725-732

Clinical, virological and phylogenetic characterization of a multiresistant HIV-1 strain outbreak in naive patients in southern Spain

Viciana I, González-Domenech CM, Palacios R, Delgado M, Del Arco A, et al. The Journal of antimicrobial chemotherapy 2016 Feb;71(2):357-61

Effectiveness of Ritonavir-Boosted Protease Inhibitor Monotherapy in Clinical Practice Even with Previous Virological Failures to Protease Inhibitor-Based Regimens

López-Cortés LF, Castaño MA, López-Ruz MA, Rios-Villegas MJ, Hernández-Quero J, et al. PloS one 2016;11(2):e0148924

Efficacy and safety of switching to abacavir/lamivudine (ABC/3TC) plus rilpivirine (RPV) in virologically suppressed HIV-infected patients on HAART

Palacios R, Pérez-Hernández IA, Martínez MA, Mayorga ML, González-Domenech CM, et al. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2016 May;35(5):815-9

Executive summary of the consensus document on psychiatric and psychological aspects in adults and children with HIV infection

Experts Panel from the Secretary of the National AIDS Plan (SPNS)., Spanish Society of Psychiatry (SEP)., AIDS Study Group (GeSIDA)., Spanish Society of Pediatric Infectious Diseases (SEIP). Electronic address: rpolor@msssi.es. Enfermedades infecciosas y microbiologia clinica 2016 Jan;34(1):54-60

Executive summary of the GESIDA/National AIDS Plan Consensus Document on Antiretroviral Therapy in Adults Infected by the Human Immunodeficiency Virus (Updated January 2016)

AIDS Study Group (GESIDA) of the Spanish Society of Infectious Diseases, Clinical Microbiology, the National AIDS Plan., AIDS Study Group (GESIDA) of the Spanish Society of Infectious Diseases, Clinical Microbiology, the National AIDS Plan. Enfermedades infecciosas y microbiologia clinica 2016 Aug-Sep;34(7):439-51

Incidence and clinical impact of infective endocarditis after transcatheter aortic valve implantation

Martínez-Sellés M, Bouza E, Díez-Villanueva P, Valerio M, Fariñas MC, et al. EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 2016 Feb;11(10):1180-7

Infective endocarditis: Absence of microbiological diagnosis is an independent predictor of inhospital mortality

Díez-Villanueva P, Muñoz P, Marín M, Bermejo J, de Alarcón González A, et al. International journal of cardiology 2016 Oct 1;220():162-5

No evidence of firstly acquired acute hepatitis C virus infection outbreak among HIV-infected patients from Southern Spain: a multicentric retrospective study from 2000-2014

Neukam K, Viciana P, Ojeda-Burgos G, Delgado-Fernández M, Ríos MJ, et al. BMC infectious diseases 2016 Sep 15;16():489

Overall and cause-specific excess mortality in HIV-positive persons compared with the general population: Role of HCV coinfection

Alejos B, Hernando V, Iribarren J, Gonzalez-García J, Hernando A, et al. Medicine 2016 Sep;95(36):e4727

Relationship between pathogenic, clinical, and virulence factors of Staphylococcus aureus in infective endocarditis versus uncomplicated bacteremia: a case-control study

Gallardo-García MM, Sánchez-Espín G, Ivanova-Georgieva R, Ruíz-Morales J, Rodríguez-Bailón I, et al. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2016 May;35(5):821-8

Validation and adhesion to GESIDA quality indicators in patients with HIV infection

Riera M, Esteban H, Suarez I, Palacios R, Lozano F, et al. Enfermedades infecciosas y microbiologia clinica 2016 Jun-Jul;34(6):346-52

Boceprevir or Telaprevir Based Triple Therapy against Chronic Hepatitis C in HIV Coinfection: Real-Life Safety and Efficacy

Neukam K, Munteanu DI, Rivero-Juárez A, Lutz T, Fehr J, et al. PloS one 2015;10(4):e0125080

Cardiovascular risk factors and lifetime risk estimation in HIV-infected patients under antiretroviral treatment in Spain

Estrada V, Bernardino JI, Masiá M, Iribarren JA, Ortega A, et al. HIV clinical trials 2015 Mar-Apr;16(2):57-65

Dimension of chronic hepatitis C virus in HIV-infected patients in the interferon-free era: an overview from south Spain

Rivero-Juarez A, Gutierrez-Valencia A, Castaño M, Merino D, Neukam K, et al. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2015 Nov;34(11):2247-55

Efficacy of and risk of bleeding during pegylated interferon plus ribavirin treatment in HIV/HCV-coinfected patients with pretreatment thrombocytopenia

Mira JA, Neukam K, López-Cortés LF, Rivero-Juárez A, Téllez F, et al. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2015 Sep;34(9):1879-84

Executive summary of the consensus document on metabolic disorders and cardiovascular risk in patients with HIV infection

Panel of experts from the Metabolic Disorders Study Group (GEAM), National Aids Plan (SPNS), Aids Study Group (GeSIDA)., Polo Rodríguez R, Galindo Puerto MJ, Dueñas C, Gómez Candela C, et al. Enfermedades infecciosas y microbiologia clinica 2015 Jan;33(1):41-7

Executive summary of the GESIDA/National AIDS Plan Consensus Document on antiretroviral therapy in adults infected by the human immunodeficiency virus (updated January 2015)

Expert Panel of GESIDA and the National AIDS Plan., Berenguer J, Polo R, Aldeguer JL, Lozano F, et al. Enfermedades infecciosas y microbiologia clinica 2015 Oct;33(8):544-56

Impact of IL28B genotype on first-week response to telaprevir-based therapy in HIV-HCV coinfection

Neukam K, Munteanu D, Haubitz S, Mira JA, Ingiliz P, et al. Antiviral therapy 2015;20(4):407-13

Left-sided infective endocarditis in patients with liver cirrhosis.

Ruiz-Morales J, Ivanova-Georgieva R, Fernández-Hidalgo N, García-Cabrera E, Miró JM, et al. The Journal of infection 2015 Dec;71(6):627-41

Low Efficacy of Pegylated Interferon plus Ribavirin plus Nitazoxanide for HCV Genotype 4 and HIV Coinfection

Macías J, López-Cortés LF, Téllez F, Recio E, Ojeda-Burgos G, et al. PloS one 2015;10(12):e0143492

Low Risk of Liver Decompensation Among Human Immunodeficiency Virus/Hepatitis C Virus-Coinfected Patients With Mild Fibrosis in the Short Term

Macías J, Mancebo M, Márquez M, Merino D, Téllez F, et al. Hepatology (Baltimore, Md.) 2015 May;61(5):1503-11

Progression of liver stiffness predicts clinical events in HIV/HCV-coinfected patients with compensated cirrhosis

Merchante N, Téllez F, Rivero-Juárez A, Ríos-Villegas MJ, Merino D, et al. BMC infectious diseases 2015 Dec 7;15():557

Serum ferritin in HIV-positive patients is related to immune deficiency and inflammatory activity

López-Calderón C, Palacios R, Cobo A, Nuño E, Ruiz J, et al. International journal of STD & AIDS 2015 May;26(6):393-7

Syphilis and human immunodeficiency virus infection: An endemic infection in men who have sex with men

González-Domenech CM, Antequera Martín-Portugués I, Clavijo-Frutos E, Márquez-Solero M, Santos-González J, et al. Enfermedades infecciosas y microbiologia clinica 2015 Jan;33(1):32-6


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