
Hematología y Hematoterapia
Lineas de Investigación
1. Estudio de factores pronóstico a nivel genómico con influencia en el tratamiento y la evolución de pacientes con hemopatías malignas. Tratamiento individualizado. Calidad de vida.
2. Trasplante de precursores hematopoyéticos.
- Trasplante de precursores hematopoyéticos domiciliario y calidad de vida.
- Influencia del genotipado KIR en el trasplante Alogénico de precursores.
- Infusión de células mesenquimales en el tratamiento de la enfermedad injerto contra huésped.
- Estudio del quimerismo hematopoyético mediante nuevas tecnologías (PCR en tiempo real y PCR digital).
3. Coagulopatías congénitas y adquiridas.
- Terapia génica en hemofilia y estudio de terapia no sustitutiva.
- Definición molecular de la enfermedad de von Willebrand.
- Definición molecular de la Purpura Trombocitopénica Idiopática.
4. Leucemia Aguda Linfoblástica infantil
- Caracterización genómica mediante secuenciación masiva de la Leucemia Aguda Linfoblástica de origen T.
- Estudios de enfermedad mínima residual en la leucemia aguda linfoblástica infantil.
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Miembros del grupo
- Todos
- IR
- Co-IR
- Investigador
- Otro

Proyectos de Investigación
CASCLIN_001 Hemofilia A con alto riesgo tanto hemorrágico como trombótico
Swedish Orphan Biovitrum ABEstudios Clínicos
Estudio de fase 2b, aleatorizado, doble ciego y controlado con placebo para evaluar los efectos de EDP-938 en adultos receptores de un trasplante de células hematopoyéticas con infección aguda de las vías respiratorias altas por el virus respiratorio sinc.
Estudio de fase 3 aleatorizado y abierto para evaluar la eficacia y la seguridad de navitoclax combinado con ruxolitinib en comparación con el mejor tratamiento disponible en pacientes con mielofibrosis en recaída/refractario (TRANSFORM-2).
Estudio de fase 1/2 de dos partes para determinar la seguridad, tolerabilidad, farmacocinética y actividad de K0706, un nuevo inhibidor de la tirosina cinasa (ITC), en pacientes sanos y pacientes con leucemia mieloide crónica (LMC) o leucemia linfoblástic.
Estudio de fase I/II, aleatorizado, abierto y de plataforma abierta en el que se evalúa la seguridad y eficacia de nuevas combinaciones de ruxolitinib en pacientes con mielofibrosis. (ADORE).
Estudio de fase Ib, abierto, aleatorizado, para evaluar la seguridad y la eficacia preliminar de Tafasitamab en combinación con R-CHOP o Tafasitamab más Lenalidomida en combinación con R-CHOP en pacientes con linfoma difuso de células B grandes (LDCBG) de.
Estudio de fase III, aleatorizado, abierto y multicéntrico, para comparar zanubrutinib (BGB-3111) más rituximab frente a bendamustina más rituximab en pacientes con linfoma de células del manto no tratados previamente que no son aptos para recibir un tras.
Estudio de fase III, aleatorizado, doble ciego, multicéntrico y controlado con placebo, de pracinostat en combinación con azacitidina en pacientes ≥ 18 años con leucemia mieloide aguda de diagnóstico reciente no aptos para la quimioterapia de inducción ha.
“IntReALL HR 2010 Estudio internacional para el tratamiento de la LLA infantil de alto riesgo 2010”.
“Estudio de fase III, abierto, aleatorizado y multicéntrico de ravulizumab en pacientes adultos y adolescentes que presentan microangiopatía trombótica (MAT) después de un trasplante de células madre hematopoyéticas (TCMH)”.
CA180406.
20120215.
BAY 80-6946 / 17833.
15-007.
AG-221-AML-005.
CAMN107AIC05.
AP24534-14-203.
CINC424C2301.
AC220-A-U302.
abr-30.
AZA-MDS-003.
CINC424B2401.
BET116183.
CINC424A2353.
200622.
MEDI4736-MDS-001.
CC-486-MDS-006.
205203.
M15-656.
LAMAN-01AN.
PonaZaero_study.
GELTAMO-O-CRT-2011.
ALODEPLETE.
BOS-IIG-01.
GS-US-406-1840.
CETB115EES03.
CAMN107A2303.
Estudio fase III, multicéntrico, abierto, aleatorizado de imatinib frente a nilotinib, en pacientes adultos con leucemia mieloide crónica cromosoma Filadelfia positivo (Ph+) en fase crónica (LMC-FC) de nuevo diagnóstico.
PAC203.
CABL001A2301.
SGN33A-005.
CC-5013-MDS-005.
Pevonedistat-2001.
LR-ESHAP.
ALL-SCT-ped-FORUM.
NKCell_LMA_2015.
MSC-EICH-2014.
Publicaciones científicas
- Todo
- D1
- Q1
- Q2
- Otro
A Randomized Open-Label Phase III Trial Evaluating the Addition of Denosumab to Standard First-Line Treatment in Advanced NSCLC: The European Thoracic Oncology Platform (ETOP) and European Organisation for Research and Treatment of Cancer (EORTC) SPLENDOUR Trial
Peters S, Danson S, Hasan B, Dafni U, Reinmuth N, Majem M, Tournoy KG, Mark MT, Pless M, Cobo M, Rodriguez-Abreu D, Falchero L, Moran T, Ortega Granados AL, Monnet I, Mohorcic K, Sureda BM, Betticher D, Demedts I, Macias JA, Cuffe S, Luciani A, Sanchez JG, Curioni-Fontecedro A, Gautschi O, Price G, Coate L, von Moos R, Zielinski C, Provencio M, Menis J, Ruepp B, Pochesci A, Roschitzki-Voser H, Besse B, Rabaglio M, O’Brien MER, Stahel RA
J Thorac Oncol 2020 Oct;15(10):1647-1656
Characterization of the Human Exposome by a Comprehensive and Quantitative Large-Scale Multianalyte Metabolomics Platform
González-Domínguez R, Jáuregui O, Queipo-Ortuño MI, Andrés-Lacueva C
Anal Chem 2020 Oct 20;92(20):13767-13775
Durvalumab With or Without Tremelimumab vs Standard Chemotherapy in First-line Treatment of Metastatic Non-Small Cell Lung Cancer: The MYSTIC Phase 3 Randomized Clinical Trial
Rizvi NA, Cho BC, Reinmuth N, Lee KH, Luft A, Ahn MJ, van den Heuvel MM, Cobo M, Vicente D, Smolin A, Moiseyenko V, Antonia SJ, Le Moulec S, Robinet G, Natale R, Schneider J, Shepherd FA, Geater SL, Garon EB, Kim ES, Goldberg SB, Nakagawa K, Raja R, Higgs BW, Boothman AM, Zhao L, Scheuring U, Stockman PK, Chand VK, Peters S; MYSTIC Investigators
JAMA Oncol 2020 May 1;6(5):661-674
Epigenetic regulation of white adipose tissue in the onset of obesity and metabolic diseases
Castellano-Castillo D, Ramos-Molina B, Cardona F, Queipo-Ortuño MI
Obes Rev 2020 Nov;21(11):e13054
Final Overall Survival and Other Efficacy and Safety Results From ASCEND-3: Phase II Study of Ceritinib in ALKi-Naive Patients With ALK-Rearranged NSCLC
Nishio M, Felip E, Orlov S, Park K, Yu CJ, Tsai CM, Cobo M, McKeage M, Su WC, Mok T, Scagliotti GV, Spigel DR, Viraswami-Appanna K, Chen Z, Passos VQ, Shaw AT
J Thorac Oncol 2020 Apr;15(4):609-617
Impact of Tumor LINE-1 Methylation Level and Neoadjuvant Treatment and Its Association with Colorectal Cancer Survival
Boughanem H, Martin-Nuñez GM, Torres E, Arranz-Salas I, Alcaide J, Morcillo S, Tinahones FJ, Crujeiras AB, Macias-Gonzalez M
J Pers Med 2020 Nov 11;10(4):219
Lurbinectedin as second-line treatment for patients with small-cell lung cancer: a single-arm, open-label, phase 2 basket trial
Trigo J, Subbiah V, Besse B, Moreno V, López R, Sala MA, Peters S, Ponce S, Fernández C, Alfaro V, Gómez J, Kahatt C, Zeaiter A, Zaman K, Boni V, Arrondeau J, Martínez M, Delord JP, Awada A, Kristeleit R, Olmedo ME, Wannesson L, Valdivia J, Rubio MJ, Anton A, Sarantopoulos J, Chawla SP, Mosquera-Martinez J, D’Arcangelo M, Santoro A, Villalobos VM, Sands J, Paz-Ares L
Lancet Oncol 2020 May;21(5):645-654
Neoadjuvant chemotherapy and nivolumab in resectable non-small-cell lung cancer (NADIM): an open-label, multicentre, single-arm, phase 2 trial
Provencio M, Nadal E, Insa A, García-Campelo MR, Casal-Rubio J, Dómine M, Majem M, Rodríguez-Abreu D, Martínez-Martí A, De Castro Carpeño J, Cobo M, López Vivanco G, Del Barco E, Bernabé Caro R, Viñolas N, Barneto Aranda I, Viteri S, Pereira E, Royuela A, Casarrubios M, Salas Antón C, Parra ER, Wistuba I, Calvo V, Laza-Briviesca R, Romero A, Massuti B, Cruz-Bermúdez A
Lancet Oncol 2020 Nov;21(11):1413-1422
Overall Survival with Osimertinib in Untreated, EGFR-Mutated Advanced NSCLC
Ramalingam SS, Vansteenkiste J, Planchard D, Cho BC, Gray JE, Ohe Y, Zhou C, Reungwetwattana T, Cheng Y, Chewaskulyong B, Shah R, Cobo M, Lee KH, Cheema P, Tiseo M, John T, Lin MC, Imamura F, Kurata T, Todd A, Hodge R, Saggese M, Rukazenkov Y, Soria JC; FLAURA Investigators
N Engl J Med 2020 Jan 2;382(1):41-50
Pembrolizumab in Microsatellite-Instability-High Advanced Colorectal Cancer
André T, Shiu KK, Kim TW, Jensen BV, Jensen LH, Punt C, Smith D, Garcia-Carbonero R, Benavides M, Gibbs P, de la Fouchardiere C, Rivera F, Elez E, Bendell J, Le DT, Yoshino T, Van Cutsem E, Yang P, Farooqui MZH, Marinello P, Diaz LA Jr; KEYNOTE-177 Investigators
N Engl J Med 2020 Dec 3;383(23):2207-2218
Programmed Cell Death Ligand 1 Expression in Untreated EGFR Mutated Advanced NSCLC and Response to Osimertinib Versus Comparator in FLAURA
Brown H, Vansteenkiste J, Nakagawa K, Cobo M, John T, Barker C, Kohlmann A, Todd A, Saggese M, Chmielecki J, Markovets A, Scott M, Ramalingam SS
J Thorac Oncol 2020 Jan;15(1):138-143
Antitumor activity of lurbinectedin in second-line small cell lung cancer patients who are candidates for re-challenge with the first-line treatment
Subbiah V, Paz-Ares L, Besse B, Moreno V, Peters S, Sala MA, López-Vilariño JA, Fernández C, Kahatt C, Alfaro V, Siguero M, Zeaiter A, Zaman K, López R, Ponce S, Boni V, Arrondeau J, Delord JP, Martínez M, Wannesson L, Antón A, Valdivia J, Awada A, Kristeleit R, Olmedo ME, Rubio MJ, Sarantopoulos J, Chawla SP, Mosquera-Martinez J, D’ Arcangelo M, Santoro A, Villalobos VM, Sands J, Trigo J
Lung Cancer 2020 Dec;150:90-96
Breast and Gut Microbiota Action Mechanisms in Breast Cancer Pathogenesis and Treatment
Laborda-Illanes A, Sanchez-Alcoholado L, Dominguez-Recio ME, Jimenez-Rodriguez B, Lavado R, Comino-Méndez I, Alba E, Queipo-Ortuño MI
Cancers (Basel) 2020 Aug 31;12(9):2465
Challenges and achievements of liquid biopsy technologies employed in early breast cancer
Alba-Bernal A, Lavado-Valenzuela R, Domínguez-Recio ME, Jiménez-Rodriguez B, Queipo-Ortuño MI, Alba E, Comino-Méndez I
EBioMedicine 2020 Dec;62:103100
CheckMate 171: A phase 2 trial of nivolumab in patients with previously treated advanced squamous non-small cell lung cancer, including ECOG PS 2 and elderly populations
Felip E, Ardizzoni A, Ciuleanu T, Cobo M, Laktionov K, Szilasi M, Califano R, Carcereny E, Griffiths R, Paz-Ares L, Duchnowska R, Garcia MA, Isla D, Jassem J, Appel W, Milanowski J, Van Meerbeeck JP, Wolf J, Li A, Acevedo A, Popat S
Eur J Cancer 2020 Mar;127:160-172
Clinical activity of a htert (vx-001) cancer vaccine as post-chemotherapy maintenance immunotherapy in patients with stage IV non-small cell lung cancer: final results of a randomised phase 2 clinical trial
Gridelli C, Ciuleanu T, Domine M, Szczesna A, Bover I, Cobo M, Kentepozidis N, Zarogoulidis K, Kalofonos C, Kazarnowisz A, Korozan M, de Las Penas R, Majem M, Chella A, Griesinger F, Bournakis E, Sadjadian P, Kotsakis A, Chinet T, Syrigos KN, Correale P, Gallou C, Jamet JM, Vetsika EK, Kosmatopoulos K, Georgoulias V; Vx-001-201 trial team
Br J Cancer 2020 May;122(10):1461-1466
Connection between the Gut Microbiome, Systemic Inflammation, Gut Permeability and FOXP3 Expression in Patients with Primary Sjögren’s Syndrome
Cano-Ortiz A, Laborda-Illanes A, Plaza-Andrades I, Membrillo Del Pozo A, Villarrubia Cuadrado A, Rodríguez Calvo de Mora M, Leiva-Gea I, Sanchez-Alcoholado L, Queipo-Ortuño MI
Int J Mol Sci 2020 Nov 19;21(22):8733
Energy System Assessment in Survivors of Breast Cancer
Cuesta-Vargas AI, Buchan J, Pajares B, Alba E, Trinidad-Fernández M, Ruiz-Medina S, García-Almeida JM, Ríos-López MJ, Roldán-Jiménez C
Phys Ther 2020 Mar 10;100(3):438-446
Epigenetics modulates the complexity of the response to Immune Checkpoint Blockade
Barragan I
EBioMedicine 2020 Oct;60:103005
Genetic and Epigenetic Biomarkers of Immune Checkpoint Blockade Response
Xiao Q, Nobre A, Piñeiro P, Berciano-Guerrero MÁ, Alba E, Cobo M, Lauschke VM, Barragán I
J Clin Med 2020 Jan 20;9(1):286
Genetic and Epigenetic Biomarkers of Immune Checkpoint Blockade Response
Xiao Q, Nobre A, Piñeiro P, Berciano-Guerrero MÁ, Alba E, Cobo M, Lauschke VM, Barragán I
J Clin Med 2020 Jan 20;9(1):286
Inertial Sensors Embedded in Smartphones as a Tool for Fatigue Assessment Based on Acceleration in Survivors of Breast Cancer
Cuesta-Vargas AI, Pajares B, Trinidad-Fernandez M, Alba E, Roldan-Jiménez C
Phys Ther 2020 Mar 10;100(3):447-456
Lung cancer symptoms at diagnosis: results of a nationwide registry study
Ruano-Raviña A, Provencio M, Calvo de Juan V, Carcereny E, Moran T, Rodriguez-Abreu D, López-Castro R, Cuadrado Albite E, Guirado M, Gómez González L, Massutí B, Ortega Granados AL, Blasco A, Cobo M, Garcia-Campelo R, Bosch J, Trigo J, Juan Ó, Aguado de la Rosa C, Dómine M, Sala M, Oramas J, Casal-Rubio J, Cerezo S
ESMO Open 2020 Nov;5(6):e001021
Microbial Signature in Adipose Tissue of Crohn’s Disease Patients
Serena C, Queipo-Ortuño M, Millan M, Sanchez-Alcoholado L, Caro A, Espina B, Menacho M, Bautista M, Monfort-Ferré D, Terrón-Puig M, Núñez-Roa C, Maymó-Masip E, Rodriguez MM, Tinahones FJ, Espin E, Martí M, Fernández-Veledo S, Vendrell J
J Clin Med 2020 Jul 31;9(8):2448
Phase I/II trial of sequential treatment of nab-paclitaxel in combination with gemcitabine followed by modified FOLFOX chemotherapy in patients with untreated metastatic exocrine pancreatic cancer: Phase I results
Carrato A, Vieitez JM, Benavides M, Rodriguez-Garrote M, Castillo A, Ogalla GD, Bermejo LG, Ruiz de Mena I, Guillén-Ponce C, Aranda E; Spanish Cooperative Group for the Treatment of Digestive Tumors (TTD)
Eur J Cancer 2020 Nov;139:51-58
Resistance to Neoadjuvant Treatment in Breast Cancer: Clinicopathological and Molecular Predictors
Chica-Parrado MR, Godoy-Ortiz A, Jiménez B, Ribelles N, Barragan I, Alba E
Cancers (Basel) 2020 Jul 22;12(8):2012
Safety of switching from intravenous to subcutaneous rituximab during first-line treatment of patients with non-Hodgkin lymphoma: the Spanish population of the MabRella study
García-Muñoz R, Quero C, Pérez-Persona E, Domingo-García A, Pérez-López C, Villaescusa-de-la-Rosa T, Martínez-Castro AM, Arguiñano-Pérez JM, Parra-Cuadrado JF, Panizo C
Br J Haematol 2020 Mar;188(5):661-673
Subclinical Arteriosclerosis is Associated With Common Vascular Risk Factors in Long-Term Survivors of Testicular Cancer
Espíldora-Hernández J, Díaz-Antonio T, Baena-Espinar J, Alonso-Calderón I, Rioja J, Alba-Conejo E, Valdivielso P, Sánchez-Chaparro MÁ
J Clin Med 2020 Mar 31;9(4):971
The Role of the Gut Microbiome in Colorectal Cancer Development and Therapy Response
Sánchez-Alcoholado L, Ramos-Molina B, Otero A, Laborda-Illanes A, Ordóñez R, Medina JA, Gómez-Millán J, Queipo-Ortuño MI
Cancers (Basel) 2020 May 29;12(6):1406
Association of uric acid levels before start of conditioning with mortality after allogeneic hematopoietic stem cell transplantation – a prospective, non-interventional study of the EBMT Transplant Complication Working Party
Penack O, Peczynski C, van der Werf S, Finke J, Ganser A, Schoemans H, Pavlu J, Niittyvuopio R, Schroyens W, Kaynar L, Blau IW, van der Velden W, Sierra J, Cortelezzi A, Wulf G, Turlure P, Rovira M, Ozkurt Z, Pascual-Cascon MJ, Moreira MC, Clausen J, Greinix H, Duarte RF, Basak GW
Haematologica 2020 Jul;105(7):1977-1983
COVID-19 severity and mortality in patients with chronic lymphocytic leukemia: a joint study by ERIC, the European Research Initiative on CLL, and CLL Campus
Scarfò L, Chatzikonstantinou T, Rigolin GM, Quaresmini G, Motta M, Vitale C, Garcia-Marco JA, Hernández-Rivas JÁ, Mirás F, Baile M, Marquet J, Niemann CU, Reda G, Munir T, Gimeno E, Marchetti M, Quaglia FM, Varettoni M, Delgado J, Iyengar S, Janssens A, Marasca R, Ferrari A, Cuéllar-García C, Itchaki G, Špaček M, De Paoli L, Laurenti L, Levin MD, Lista E, Mauro FR, Šimkovič M, Van Der Spek E, Vandenberghe E, Trentin L, Wasik-Szczepanek E, Ruchlemer R, Bron D, De Paolis MR, Del Poeta G, Farina L, Foglietta M, Gentile M, Herishanu Y, Herold T, Jaksic O, Kater AP, Kersting S, Malerba L, Orsucci L, Popov VM, Sportoletti P, Yassin M, Pocali B, Barna G, Chiarenza A, Dos Santos G, Nikitin E, Andres M, Dimou M, Doubek M, Enrico A, Hakobyan Y, Kalashnikova O, Ortiz Pareja M, Papaioannou M, Rossi D, Shah N, Shrestha A, Stanca O, Stavroyianni N, Strugov V, Tam C, Zdrenghea M, Coscia M, Stamatopoulos K, Rossi G, Rambaldi A, Montserrat E, Foà R, Cuneo A, Ghia P
Leukemia 2020 Sep;34(9):2354-2363
COVID-19 severity and mortality in patients with chronic lymphocytic leukemia: a joint study by ERIC, the European Research Initiative on CLL, and CLL Campus
Scarfò L, Chatzikonstantinou T, Rigolin GM, Quaresmini G, Motta M, Vitale C, Garcia-Marco JA, Hernández-Rivas JÁ, Mirás F, Baile M, Marquet J, Niemann CU, Reda G, Munir T, Gimeno E, Marchetti M, Quaglia FM, Varettoni M, Delgado J, Iyengar S, Janssens A, Marasca R, Ferrari A, Cuéllar-García C, Itchaki G, Špaček M, De Paoli L, Laurenti L, Levin MD, Lista E, Mauro FR, Šimkovič M, Van Der Spek E, Vandenberghe E, Trentin L, Wasik-Szczepanek E, Ruchlemer R, Bron D, De Paolis MR, Del Poeta G, Farina L, Foglietta M, Gentile M, Herishanu Y, Herold T, Jaksic O, Kater AP, Kersting S, Malerba L, Orsucci L, Popov VM, Sportoletti P, Yassin M, Pocali B, Barna G, Chiarenza A, Dos Santos G, Nikitin E, Andres M, Dimou M, Doubek M, Enrico A, Hakobyan Y, Kalashnikova O, Ortiz Pareja M, Papaioannou M, Rossi D, Shah N, Shrestha A, Stanca O, Stavroyianni N, Strugov V, Tam C, Zdrenghea M, Coscia M, Stamatopoulos K, Rossi G, Rambaldi A, Montserrat E, Foà R, Cuneo A, Ghia P
Leukemia 2020 Sep;34(9):2354-2363
Helpful Criteria When Implementing NGS Panels in Childhood Lymphoblastic Leukemia
Vega-Garcia N, Benito R, Esperanza-Cebollada E, Llop M, Robledo C, Vicente-Garcés C, Alonso J, Barragán E, Fernández G, Hernández-Sánchez JM, Martín-Izquierdo M, Maynou J, Minguela A, Montaño A, Ortega M, Torrebadell M, Cervera J, Sánchez J, Jiménez-Velasco A, Riesco S, Hernández-Rivas JM, Lassaletta Á, Fernández JM, Rives S, Dapena JL, Ramírez M, Camós M, On Behalf Of The Group Of Leukemia Of The Spanish Society Of Pediatric Hematology And Oncology Sehop
J Pers Med 2020 Nov 26;10(4):244
Association of Serum Ferritin Levels Before Start of Conditioning With Mortality After alloSCT – A Prospective, Non-interventional Study of the EBMT Transplant Complications Working Party
Penack O, Peczynski C, van der Werf S, Finke J, Ganser A, Schoemans H, Pavlu J, Niittyvuopio R, Schroyens W, Kaynar L, Blau IW, van der Velden WJFM, Sierra J, Cortelezzi A, Wulf G, Turlure P, Rovira M, Ozkurt Z, Pascual-Cascon MJ, Moreira MC, Clausen J, Greinix H, Duarte RF, Basak GW
Front Immunol 2020 Apr 15;11:586
Blinatumomab and inotuzumab for B cell precursor acute lymphoblastic leukaemia in children: a retrospective study from the Leukemia Working Group of the Spanish Society of Pediatric Hematology and Oncology (SEHOP)
Fuster JL, Molinos-Quintana A, Fuentes C, Fernández JM, Velasco P, Pascual T, Rives S, Dapena JL, Sisinni L, López-Godino O, Palomo P, Villa-Alcázar M, Bautista F, González-Vicent M, López-Duarte M, García-Morín M, Ramos-Elbal E, Ramírez M; Leukemia Working Group of the Spanish Society of Pediatric Hematology, Oncology (SEHOP)
Br J Haematol 2020 Sep;190(5):764-771
LncRNA-mRNA Co-Expression Analysis Identifies AL133346
Cuadros M, García DJ, Andrades A, Arenas AM, Coira IF, Baliñas-Gavira C, Peinado P, Rodríguez MI, Álvarez-Pérez JC, Ruiz-Cabello F, Camós M, Jiménez-Velasco A, Medina PP
1/CCN2 as Biomarkers in Pediatric B-Cell Acute Lymphoblastic Leukemia Cancers (Basel)
PLZF-RARα, NPM1-RARα, and Other Acute Promyelocytic Leukemia Variants: The PETHEMA Registry Experience and Systematic Literature Review
Sobas M, Talarn-Forcadell MC, Martínez-Cuadrón D, Escoda L, García-Pérez MJ, Mariz J, Mela-Osorio MJ, Fernández I, Alonso-Domínguez JM, Cornago-Navascués J, Rodríguez-Macias G, Amutio ME, Rodríguez-Medina C, Esteve J, Sokół A, Murciano-Carrillo T, Calasanz MJ, Barrios M, Barragán E, Sanz MA, Montesinos P
Cancers (Basel) 2020 May 21;12(5):1313
Reconstitution of cytomegalovirus-specific T-cell immunity following unmanipulated haploidentical allogeneic hematopoietic stem cell transplantation with posttransplant cyclophosphamide
Huntley D, Giménez E, Pascual MJ, Remigia MJ, Amat P, Vázquez L, Hernández M, Hernández-Boluda JC, Gago B, Piñana JL, García M, Martínez A, Mateo E, Gozalbo-Rovira R, Albert E, Solano C, Navarro D
Bone Marrow Transplant 2020 Jul;55(7):1347-1356
Association of uric acid levels before start of conditioning with mortality after allogeneic hematopoietic stem cell transplantation – a prospective, non-interventional study of the EBMT Transplant Complication Working Party
Penack O, Peczynski C, van der Werf S, Finke J, Ganser A, Schoemans H, Pavlu J, Niittyvuopio R, Schroyens W, Kaynar L, Blau IW, van der Velden W, Sierra J, Cortelezzi A, Wulf G, Turlure P, Rovira M, Ozkurt Z, Pascual-Cascon MJ, Moreira MC, Clausen J, Greinix H, Duarte RF, Basak GW
Haematologica 2020 Jul;105(7):1977-1983
COVID-19 severity and mortality in patients with chronic lymphocytic leukemia: a joint study by ERIC, the European Research Initiative on CLL, and CLL Campus
Scarfò L, Chatzikonstantinou T, Rigolin GM, Quaresmini G, Motta M, Vitale C, Garcia-Marco JA, Hernández-Rivas JÁ, Mirás F, Baile M, Marquet J, Niemann CU, Reda G, Munir T, Gimeno E, Marchetti M, Quaglia FM, Varettoni M, Delgado J, Iyengar S, Janssens A, Marasca R, Ferrari A, Cuéllar-García C, Itchaki G, Špaček M, De Paoli L, Laurenti L, Levin MD, Lista E, Mauro FR, Šimkovič M, Van Der Spek E, Vandenberghe E, Trentin L, Wasik-Szczepanek E, Ruchlemer R, Bron D, De Paolis MR, Del Poeta G, Farina L, Foglietta M, Gentile M, Herishanu Y, Herold T, Jaksic O, Kater AP, Kersting S, Malerba L, Orsucci L, Popov VM, Sportoletti P, Yassin M, Pocali B, Barna G, Chiarenza A, Dos Santos G, Nikitin E, Andres M, Dimou M, Doubek M, Enrico A, Hakobyan Y, Kalashnikova O, Ortiz Pareja M, Papaioannou M, Rossi D, Shah N, Shrestha A, Stanca O, Stavroyianni N, Strugov V, Tam C, Zdrenghea M, Coscia M, Stamatopoulos K, Rossi G, Rambaldi A, Montserrat E, Foà R, Cuneo A, Ghia P
Leukemia 2020 Sep;34(9):2354-2363
Haploidentical transplantation in high-risk pediatric leukemia: A retrospective comparative analysis on behalf of the Spanish working Group for bone marrow transplantation in children (GETMON) and the Spanish Grupo for hematopoietic transplantation (GETH)
Pérez-Martínez A, Ferreras C, Pascual A, Gonzalez-Vicent M, Alonso L, Badell I, Fernández Navarro JM, Regueiro A, Plaza M, Pérez Hurtado JM, Benito A, Beléndez C, Couselo JM, Fuster JL, Díaz-Almirón M, Bueno D, Mozo Y, Marsal J, Gómez López A, Sisinni L, de Heredia CD, Díaz MÁ
Am J Hematol 2020 Jan;95(1):28-37
Helpful Criteria When Implementing NGS Panels in Childhood Lymphoblastic Leukemia
Vega-Garcia N, Benito R, Esperanza-Cebollada E, Llop M, Robledo C, Vicente-Garcés C, Alonso J, Barragán E, Fernández G, Hernández-Sánchez JM, Martín-Izquierdo M, Maynou J, Minguela A, Montaño A, Ortega M, Torrebadell M, Cervera J, Sánchez J, Jiménez-Velasco A, Riesco S, Hernández-Rivas JM, Lassaletta Á, Fernández JM, Rives S, Dapena JL, Ramírez M, Camós M, On Behalf Of The Group Of Leukemia Of The Spanish Society Of Pediatric Hematology And Oncology Sehop
J Pers Med 2020 Nov 26;10(4):244
Association of Serum Ferritin Levels Before Start of Conditioning With Mortality After alloSCT – A Prospective, Non-interventional Study of the EBMT Transplant Complications Working Party
Penack O, Peczynski C, van der Werf S, Finke J, Ganser A, Schoemans H, Pavlu J, Niittyvuopio R, Schroyens W, Kaynar L, Blau IW, van der Velden WJFM, Sierra J, Cortelezzi A, Wulf G, Turlure P, Rovira M, Ozkurt Z, Pascual-Cascon MJ, Moreira MC, Clausen J, Greinix H, Duarte RF, Basak GW
Front Immunol 2020 Apr 15;11:586
Blinatumomab and inotuzumab for B cell precursor acute lymphoblastic leukaemia in children: a retrospective study from the Leukemia Working Group of the Spanish Society of Pediatric Hematology and Oncology (SEHOP)
Fuster JL, Molinos-Quintana A, Fuentes C, Fernández JM, Velasco P, Pascual T, Rives S, Dapena JL, Sisinni L, López-Godino O, Palomo P, Villa-Alcázar M, Bautista F, González-Vicent M, López-Duarte M, García-Morín M, Ramos-Elbal E, Ramírez M; Leukemia Working Group of the Spanish Society of Pediatric Hematology, Oncology (SEHOP)
Br J Haematol 2020 Sep;190(5):764-771
LncRNA-mRNA Co-Expression Analysis Identifies AL133346
Cuadros M, García DJ, Andrades A, Arenas AM, Coira IF, Baliñas-Gavira C, Peinado P, Rodríguez MI, Álvarez-Pérez JC, Ruiz-Cabello F, Camós M, Jiménez-Velasco A, Medina PP
1/CCN2 as Biomarkers in Pediatric B-Cell Acute Lymphoblastic Leukemia Cancers (Basel)
PLZF-RARα, NPM1-RARα, and Other Acute Promyelocytic Leukemia Variants: The PETHEMA Registry Experience and Systematic Literature Review
Sobas M, Talarn-Forcadell MC, Martínez-Cuadrón D, Escoda L, García-Pérez MJ, Mariz J, Mela-Osorio MJ, Fernández I, Alonso-Domínguez JM, Cornago-Navascués J, Rodríguez-Macias G, Amutio ME, Rodríguez-Medina C, Esteve J, Sokół A, Murciano-Carrillo T, Calasanz MJ, Barrios M, Barragán E, Sanz MA, Montesinos P
Cancers (Basel) 2020 May 21;12(5):1313
Reconstitution of cytomegalovirus-specific T-cell immunity following unmanipulated haploidentical allogeneic hematopoietic stem cell transplantation with posttransplant cyclophosphamide
Huntley D, Giménez E, Pascual MJ, Remigia MJ, Amat P, Vázquez L, Hernández M, Hernández-Boluda JC, Gago B, Piñana JL, García M, Martínez A, Mateo E, Gozalbo-Rovira R, Albert E, Solano C, Navarro D
Bone Marrow Transplant 2020 Jul;55(7):1347-1356
Dasatinib discontinuation in patients with chronic-phase chronic myeloid leukemia and stable deep molecular response: the DASFREE study
Shah NP, García-Gutiérrez V, Jiménez-Velasco A, Larson S, Saussele S, Rea D, Mahon FX, Levy MY, Gómez-Casares MT, Pane F, Nicolini FE, Mauro MJ, Sy O, Martin-Regueira P, Lipton JH
Leuk Lymphoma 2020 Mar;61(3):650-659
Management experience of advanced-stage mycosis fungoides/Sézary syndrome: a retrospective study from Spanish haematology referral units
Novelli S, Martín A, Sánchez JJ, Espeso M, Mozos A, Briones J
Eur J Dermatol 2020 Aug 1;30(4):397-403
Potential Survival Benefit for Patients Receiving Allogeneic Hematopoietic Stem Cell Transplantation after Nivolumab Therapy for Relapse/Refractory Hodgkin Lymphoma: Real-Life Experience in Spain
Martínez C, Carpio C, Heras I, Ríos-Herranz E, Buch J, Gutierrez A, Romero S, Zeberio I, García-García I, Rodriguez-Izquierdo A, Alonso R, Bargay J, Barrenetxea C, Domingo-Doménech E, de Haro ME, Palomera L, García-Sanz R; Spanish Group of Lymphoma and Bone Marrow Transplantation (GELTAMO)
Biol Blood Marrow Transplant 2020 Aug;26(8):1534-1542
Predicting Survival after Allogeneic Hematopoietic Cell Transplantation in Myelofibrosis: Performance of the Myelofibrosis Transplant Scoring System (MTSS) and Development of a New Prognostic Model
Hernández-Boluda JC, Pereira A, Alvarez-Larran A, Martín AA, Benzaquen A, Aguirre L, Mora E, González P, Mora J, Dorado N, Sampol A, García-Gutiérrez V, López-Godino O, Fox ML, Reguera JL, Pérez-Encinas M, Pascual MJ, Xicoy B, Parody R, González-Pinedo L, Español I, Avendaño A, Correa JG, Vallejo C, Jurado M, García-Cadenas I, Osorio S, Durán MA, Sánchez-Guijo F, Cervantes F, Piñana JL
Biol Blood Marrow Transplant 2020 Dec;26(12):2237-2244
Study protocol for a phase II, multicentre, prospective, non-randomised clinical trial to assess the safety and efficacy of infusing allogeneic activated and expanded natural killer cells as consolidation therapy for paediatric acute myeloblastic leukaemia
Muñoz Builes M, Vela Cuenca M, Fuster Soler JL, Astigarraga I, Pascual Martínez A, Vagace Valero JM, Tong HY, Valentín Quiroga J, Fernández Casanova L, Escudero López A, Sisinni L, Blanquer M, Mirones Aguilar I, González Martínez B, Borobia AM, Pérez-Martínez A
BMJ Open 2020 Jan 8;10(1):e029642
An investigation of the utility of plasma Cytomegalovirus (CMV) microRNA detection to predict CMV DNAemia in allogeneic hematopoietic stem cell transplant recipients
Talaya A, Giménez E, Pascual MJ, Gago B, Piñana JL, Hernández-Boluda JC, Vázquez L, García M, Serrano D, Hernández M, Albert E, Solano C, Navarro D
Med Microbiol Immunol 2020 Feb;209(1):15-21
Incidence, features, and outcomes of cytomegalovirus DNAemia in unmanipulated haploidentical allogeneic hematopoietic stem cell transplantation with post-transplantation cyclophosphamide
Huntley D, Giménez E, Pascual MJ, Hernández-Boluda JC, Gago B, Vázquez L, Piñana JL, García M, Pérez A, Serrano D, Hernández M, Albert E, Solano C, Navarro D
Transpl Infect Dis 2020 Feb;22(1):e13206
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