Lineas de Investigación
Estudio de las bases biológicas del comportamiento y la fisiopatología de enfermedades degenerativas de gran prevalencia. Estas incluyen los trastornos adictivos (abuso de drogas), los trastornos de la alimentación (obesidad, diabetes, dislipemia), la enfermedad de Alzheimer, así como los síndromes de ansiedad y depresión, a lo largo del desarrollo y en modelos de enfermedad (comorbilidad psiquiátrica)..
01. Esteatohepatitis alcohólica y no alcohólica.
02. Programación metabólica durante el desarrollo y crecimiento (obesidad, diabetes)
03. Desarrollo de nuevas entidades químicas terapéuticas o nuevas indicaciones de fármacos existentes.
04 Evaluación farmacológica de alimentos de uso médico especial (ADUME).
Miembros del grupo
- Todos
- IR
- Co-IR
- Investigador
- Tecnico Laboratorio
- Otro
Proyectos de Investigación
Área 3.Neurociencias, Cronicidad, Envejecimiento y Salud en poblaciones vulnerables.PLAN PROPIO_AREA 3
Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
.
2020
MOV20-002 Análisis de perfiles inflamatorios en pacientes usuarios con trastornos psiquiátricos comorbidos: Depresión, Deterioro cognitivo y uso de alcohol. Candidato: María Flores López. Jefe de Grupo: Antonia María Serrano Criado
Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
.
2020
MOV20-001 Análisis del mecanismo de autofagia en modelos animales de Alzheimer de última generación. Candidato: Dina Medina Vera, Jefe de Grupo: Fernando Rodríguez de Fonseca
Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
.
2020
CD20/00192 Contratos Sara Borrell 2020 Sara Peñasco Iglesias. Jefe de Grupo: Fernando Rodriguez de Fonseca
Instituto de Salud Carlos III
.
2020
PI20/01399 Papel de la señalización lipídica mediada por monoacilgliceroles y ácido lisofosfatídico en la Asociación entre trastornos por uso de alcohol y Depresión: Identificación de Biomarcadores
Instituto de Salud Carlos III
.
2020
P18-TP-5194 VALIDACIÓN PRECLINICA DE LOS INOSITOLES DE LA ALGARROBA SOBRE TRASTORNOS ASOCIADOS A LA RESISTENCIA INSULINICA
Consejería de Transformación Económica, Industria, Conocimiento y Universidades
.
2020
RTC2019-007329-1 Obtención de principios activos antioxidantes a partir de la vaina del algarrobo y validación de su potencial terapéutico. Fernando Rodriguez de Fonseca.
Agencia Estatal de Investigación
.
2020
COV20/00157 Afectación neurológica en la enfermedad Covid-19 clinicamente relevante. ¿Existe la enfermedad Neuro-Covid-19?
Instituto de Salud Carlos III
.
2020
Euronutra S.L. RRHH
Euronutra
Estancia de investigación en Euronutra S.L.
2021
IFI18/00042 Contrato i-PFIS 2018 Antonio Jesús López Gambero.
Instituto de Salud Carlos III (ISCIII)
Acción Estratégica en Salud 2019 AES 2018
2018
RTC2019-007329-1: Obtención de principios activos antioxidantes a partir de la vaina del algarrobo y validación de su potencial terapéutico | El objetivo tecnológico principal de esta línea de I+D se basa en la extracción y obtención de principios activos naturales de una fracción del fruto del algarrobo para el tratamiento de enfermedades metabólicas crónicas como el NASH, del neurodesarrollo (síndrome de Down, síndrome de X-Frágil) y psiquiátricas infantiles (trastorno por déficit de atención e hiperactividad, TDH), sin tratamiento específico que cursan con deterioro metabólico y/o cognitivo abordando para ello el diseño e ingeniería de una tecnología complementaria que permita desarrollar y completar el reto que supone el presente proyecto.
Agencia Estatal de Investigación. Ministerio de Ciencia e Innovación
Proyectos de I+D+I «Retos Colaboración.
2019
Papel de la señalización lipídica mediada por monoacilgliceroles y ácido lisofosfatídico en la asociación entre trastornos por uso de alcohol y depresión: iIdentificación de biomarcadores.
ISCIII
.
2021
MV19/00060 Papel de las aciletanolamidas y los acilgliceroles en el consumo abusivo de alcohol durante la adolescencia y la vulnerabilidad a desarrollar trastornos por uso de alcohol.
ISCIII
.
2019
PEIBA-2019-040 BIOMARCADORES CIRCULANTES DE COMORBILIODAD NEUROLÓGICA EN EL TRASTORNO POR CONSUMO TEMPRANO DE ALCOHOL Y/O DROGAS ILEGALES: HERRAMIENTA PREDICTIVA DE DETERIORO COGNITIVO Y DEMENCIAS EN POBLACIONES VULNERABLES.
Ministerio de Sanidad, Consumo y Bienestar Social
.
2019
PI19/00343 Estudio de nuevos factores del sistema GH/IGF: análisis de mecanismos moleculares que regulan crecimiento y metabolismo mediane PAPP-A2 y desarrollo de nuevas terapias.
ISCIII
.
2019
CPII19/00031 Contratos Miguel Servet Tipo II 2019
ISCIII
.
2019
EIN2019-103364 – INNOVATIVE DUAL LIGANDS FOR THE TREATMENT OF ALCOHOL USE DISORDERS AND ITS COMPLICATIONS
Agencia Estatal de Investigación
.
2019
DTS19/00125 Evaluación preclínica de ligandos duales para el tratamiento de los trastornos por uso de alcohol
ISCIII
.
2019
PI19/01577 Alcohol, depresión y deterioro cognitivo: Papel de las aciletanolamidas no cannabinoides. IP Fernando Rodriguez de Fonseca
ISCIII
.
2019
PI19/01577 Alcohol, depresión y deterioro cognitivo: Papel de las aciletanolamidas no cannabinoides. IP Fernando Rodriguez de Fonseca
ISCIII
.
2019
Estancia Universidad de Roma-Sapienza
Sapienza University of Roma
.
2019
ERASMUS+: Intestinal Neoplasia
ISCIII
.
2019
FATZHEIMER: High Fat Diet, Microbiota and Neuroinflammation in the Progression of Alzheimer Disease
European Comission (H2020)
EU-LAC Health
2018
Consumo de alcohol durante la adolescencia: Papel del sistema endocannabinoide en el desarrollo de adicción al alcohol y trastornos afectivos y de ansiedad comórbidos.
Ministerio de Sanidad, Servicios Sociales e Igualdad
Plan Nacional sobre Drogas
2018
Papel del ácido lisofosfatídico en el alcoholismo y la cormobilidad psiquiátrica: implicaciones terapéuticas y evaluación de biomarcadores
CONSEJERÍA DE SALUD
: Proyectos de Investigación biomédica y en ciencias de la salud. Consejería de Salud
2016
Early life stress and excessive alcohol consumption in adolescents: Role of the endocannabinoid system in the vulnerability to alcoholism
INSTITUTO DE SALUD CARLOS III
Proyecto de Investigación Miguel Servet Tipo I. Instituto de Salud Carlos III.
2015
Red de Trastornos Adictivos (Red RTA)
INSTITUTO DE SALUD CARLOS III
RETICS. Instituto de Salud Carlos III. Ministerio de Ciencia e Innovación
2013
Implicación del Sistema endocannabinoide en la vulnerabilidad al alcoholismo en adultos tras el consumo abusivo durante la adolescencia
CONSEJERÍA DE SALUD
Consejería de Salud
2013
CD17/00125 Sara Borrell 2017 Victor Echeverry Alzaty.Jefe de Grupo Fernando Rodriguez de Fonseca
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS SARA BORRELL
2017
FI17/00027 Contrato PFIS 2017 Laura Sanchez Marin.Jefe de Grupo: Fernando Rodriguez de Fonseca
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS PFIS: CONTRATOS PREDOCTORALES DE FORMACIÓN EN INVESTIGACIÓN EN SALUD
2017
PI-0139-2018 ESTUDIO DE LA ACTIVACIÓN DEL RECEPTOR PARA GLP1 COMO BASE DEL DESARROLLO DE TERAPIAS COMBINADAS PARA EL TRATAMIENTO DE LA ESTEATOHEPATITIS NO ALCOHÓLICA
CONSEJERÍA DE SALUD
PROYECTOS DE INVESTIGACIÓN EN SALUD
2018
CPII17/00024 Miiguel Servet Tipo II 2017 Juan Suarez Pérez
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS MIGUEL SERVET TIPO II
2017
PI16/01374 Obesidad infantil grave de comienzo precoz al diagnóstico y tras pérdida ponderal: Fundamentos metabólicos, hormonales, genéticos, genómicos, metabolómicos y de microbiota
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD
2016
RC-0003-2018 Acción C Nicolás Monarde F.Rodríguez de Fonseca
SERVICIO ANDALUZ DE SALUD
RENOVACIÓN ACCIÓN C (PROGRAMA NICOLÁS MONARDES) DE LA CONVOCATORIA
2018
PRX18/00608 Estancias de movilidad de profesores e investigadores seniores en centros extranjeros de enseñanza superior e investigación, incluido el Programa Salvador de Madariaga 2018. Investigador: Fernando Antonio Rodríguez de Fonseca
MINISTERIO DE EDUCACIÓN Y FORMACIÓN PROFESIONAL
ESTANCIAS PROGRAMA SALVADOR DE MADARIAGA
2018
RD16/0017/0001 Red de Trastornos Adictivos
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONVOCATORIA DE REDES TEMÁTICAS DE INVESTIGACIÓN COOPERATIVA EN SALUD (RETICS)
2016
PND2018/044 BIOMARCADORES CIRCULANTES DE COMORBILIDAD PSIQUIÁTRICA EN EL TRASTORNO POR USO DE DROGAS: COMPARACIÓN CON BIOMARCADORES DE TRASTORNO DEPRESIVO Y TRASTORNO PSICÓTICO
MINISTERIO DE SANIDAD, CONSUMO Y BIENESTAR SOCIAL
PROYECTOS DE INVESTIGACIÓN SOBRE ADICCIONES
2018
RTC-2016-4983-1 Diseño, ingeniería y ensamblaje de línea piloto de nuevos extractos naturales solvent free y validacion in vivo de compuestos bioactivos
MINISTERIO DE ECONOMIA Y EMPRESA
AYUDAS PARA I+D+i RETOS COLABORACIÓN
2016
PI16/01698 Lípidos transmisores derivados del ácido oleico: Estudio traslacional de su papel en los trastornos por uso de alcohol
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD
2016
DTS16/00115 Desarrollo de nuevos conjugados de ácidos grasos para el tratamiento de las esteatohepatitis
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE DESARROLLO TECNOLÓGICO EN SALUD
2016
PSI2015-73156-JIN Incremento de la neurogénesis hipocampal adulta como estrategia terapéutica para las alteraciones conductuales inducidas por cocaína (COCANEUROGNSIS)
MINISTERIO DE ECONOMIA Y EMPRESA
PROYECTOS I+D+i PARA JÓVENES INVESTIGADORES
2015
MS14/00173 Contrato Miguel Servet Tipo I Antonia Mª Serrano Criado
INSTITUTO DE SALUD CARLOS III
CONTRATOS MIGUEL SERVET TIPO I
2014
2017i043 Consumo de alcohol durante la adolescencia: papel del sistema endocannabinoide en el desarrollo de adicción al alcohol y trastornos afectivos y de ansiedad comórbidos
MINISTERIO DE SANIDAD, CONSUMO Y BIENESTAR SOCIAL
PROYECTOS DE INVESTIGACIÓN SOBRE ADICCIONES
2017
PI17/02026 Estudio Traslacional del Papel del Sistema Endocannabinoide en la Amígdala Ampliada en la Ansiedad Asociada a la Dependencia Alcohólica
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD (FIS)
2017
Publicaciones científicas
- Todo
- D1
- Q1
- Q2
- Otro
Discovery of V-0219: A Small-Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 Receptor toward Oral Treatment for “Diabesity”.
Decara, Juan M; Vazquez-Villa, Henar; Brea, Jose; Alonso, Monica; Srivastava, Raj Kamal; Orio, Laura; Alen, Francisco; Suarez, Juan; Baixeras, Elena; Garcia-Carceles, Javier; Escobar-Pena, Andrea; Lutz, Beat; Rodriguez, Ramon; Codesido, Eva; Garcia-Ladona, F Javier; Bennett, Teresa A; Ballesteros, Juan A; Cruces, Jacobo; Loza, Maria I; Benhamu, Bellinda; Rodriguez de Fonseca, Fernando; Lopez-Rodriguez, Maria L…Less Journal of medicinal chemistry 2022
A combination of circulating chemokines as biomarkers of obesity-induced insulin resistance at puberty
Rivera, P; Martos-Moreno, GA; Barrios, V; Suarez, J; Pavon, FJ; Chowen, JA; de Fonseca, FR; Argente, J PEDIATRIC OBESITY 2021
A Negative Energy Balance Is Associated with Metabolic Dysfunctions in the Hypothalamus of a Humanized Preclinical Model of Alzheimer’s Disease, the 5XFAD Mouse
López-Gambero AJ, Rosell-Valle C, Medina-Vera D, Navarro JA, Vargas A, et al. International journal of molecular sciences 2021 May 20;22(10):
Abrupt cessation of reboxetine along alcohol deprivation results in alcohol intake escalation after reinstatement of drinking
Ballesta, A; Alen, F; Orio, L; Arco, R; Vadas, E; Decara, J; Vargas, A; de Heras, RG; Ramirez-Lopez, M; Serrano, A; Pavon, FJ; Suarez, J; de Fonseca, FR ADDICTION BIOLOGY 2021
Activation of Macrophages by Lysophosphatidic Acid through the Lysophosphatidic Acid Receptor 1 as a Novel Mechanism in Multiple Sclerosis Pathogenesis
Fransson, J; Gomez-Conde, AI; Romero-Imbroda, J; Fernandez, O; Leyva, L; de Fonseca, FR; Chun, J; Louapre, C; Van-Evercooren, AB; Zujovic, V; Estivill-Torrus, G; Garcia-Diaz, B MOLECULAR NEUROBIOLOGY 2021
Activation of PI3K/Akt Signaling Pathway in Rat Hypothalamus Induced by an Acute Oral Administration of D-Pinitol
Medina-Vera D, Navarro JA, Tovar R, Rosell-Valle C, Gutiérrez-Adan A, et al. Nutrients 2021 Jun 30;13(7):
Adolescent binge-ethanol accelerates cognitive impairment and beta-amyloid production and dysregulates endocannabinoid signaling in the hippocampus of APP/PSE mice
Ledesma, JC; Rodriguez-Arias, M; Gavito, AL; Sanchez-Perez, AM; Vina, J; Vera, DM; de Fonseca, FR; Minarro, J ADDICTION BIOLOGY 2021
Analysis of Both Lipid Metabolism and Endocannabinoid Signaling Reveals a New Role for Hypothalamic Astrocytes in Maternal Caloric Restriction-Induced Perinatal Programming
Tovar R, Vargas A, Aranda J, Sánchez-Salido L, González-González L, et al. International journal of molecular sciences 2021 Jun 11;22(12):
ATP13A2 levels in serum and cerebrospinal fluid in patients with idiopathic Parkinson’s disease
Fernandez-Espejo, E; de Fonseca, FR; Suarez, J; Gonzalez-Aparicio, R; Santurtun, A PARKINSONISM & RELATED DISORDERS 2021
Cerebellar and cortical TLR4 activation and behavioral impairments in Wernicke-Korsakoff Syndrome: Pharmacological effects of oleoylethanolamide
Moya, M; San Felipe, D; Ballesta, A; Alen, F; de Fonseca, FR; Garcia-Bueno, B; Marco, EM; Orio, L PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY 2021
Cerebrospinal fluid lactoperoxidase level is enhanced in idiopathic Parkinson’s disease, and correlates with levodopa equivalent daily dose
Fernandez-Espejo, E; de Fonseca, FR; Suarez, J; de Pablos, AM BRAIN RESEARCH 2021
Chronic central modulation of LPA/LPA receptors-signaling pathway in the mouse brain regulates cognition, emotion, and hippocampal neurogenesis
Rosell-Valle, C; Pedraza, C; Manuel, I; Moreno-Rodriguez, M; Rodriguez-Puertas, R; Castilla-Ortega, E; Carames, JM; Conde, AIG; Zambrana-Infantes, E; Ortega-Pinazo, J; Serrano-Castro, PJ; Chun, J; De Fonseca, FR; Santin, LJ; Estivill-Torrus, G PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY 2021
Cocaine and depressive disorders: When standard clinical diagnosis is insufficient
Alias-Ferri, M; Garcia-Marchena, N; Mestre-Pinto, JI; Araos, P; Vergara-Moragues, E; Fonseca, F; Gonzalez-Saiz, F; de Fonseca, FR; Torrens, M; Mateus, J; Papaseit, E; Perez-Mana, C; Rodriguez-Minguela, R; Rossi, P; Tamarit, C; Vallecillo, G ADICCIONES 2021
Energy sensors in drug addiction: A potential therapeutic target
Lopez-Gambero, AJ; de Fonseca, FR; Suarez, J ADDICTION BIOLOGY 2021
Environmental Enrichment Rescues Endocannabinoid-Dependent Synaptic Plasticity Lost in Young Adult Male Mice after Ethanol Exposure during Adolescence
Rico-Barrio I, Peñasco S, Lekunberri L, Serrano M, Egaña-Huguet J, et al. Biomedicines 2021 Jul 16;9(7):
Evaluation of neurotrophic factors and education level as predictors of cognitive decline in alcohol use disorder
Requena-Ocaña N, Araos P, Flores M, García-Marchena N, Silva-Peña D, et al. Scientific reports 2021 Aug 2;11(1):15583
GABAergic deficits in absence of LPA(1) receptor, associated anxiety-like and coping behaviors, and amelioration by interneuron precursor transplants into the dorsal hippocampus
Rosell-Valle, C; Martinez-Losa, M; Matas-Rico, E; Castilla-Ortega, E; Zambrana-Infantes, E; Gomez-Conde, AI; Sanchez-Salido, L; de Guevara-Miranda, DL; Pedraza, C; Serrano-Castro, PJ; Chun, J; de Fonseca, FR; Alvarez-Dolado, M; Santin, LJ; Estivill-Torrus, G BRAIN STRUCTURE & FUNCTION 2021
Gender Perspective in Dual Diagnosis
Torrens-Melich M, Orengo T, Rodríguez de Fonseca F, Almodóvar I, Baquero A, et al. Brain sciences 2021 Aug 21;11(8):
Genetic deletion of dopamine D1 receptors increases the sensitivity to cannabinoid CB1 receptor antagonist-precipitated withdrawal when compared with wild-type littermates: studies in female mice repeatedly exposed to the Spice cannabinoid HU-210
Serrano, A; Vadas, E; Ferrer, B; Bilbao, A; Granado, N; Suarez, J; Pavon, FJ; Moratalla, R; de Fonseca, FR PSYCHOPHARMACOLOGY 2021
Immunomodulatory, Antioxidant Activity and Cytotoxic Effect of Sulfated Polysaccharides from Porphyridium cruentum. (S.F.Gray) Nageli
Casas-Arrojo V, Decara J, de Los Ángeles Arrojo-Agudo M, Pérez-Manríquez C, Abdala-Díaz RT Biomolecules 2021 Mar 24;11(4):
Influence of gender and education on cocaine users in an outpatient cohort in Spain
Requena-Ocaña N, Flores-Lopez M, Martín AS, García-Marchena N, Pedraz M, et al. Scientific reports 2021 Oct 22;11(1):20928
Met and Unmet Needs in an Inpatient Psychiatry Setting in Spain
Gomez-Sanchez-Lafuente C, Guzman-Parra J, Lopez-Zambrano MA, Moreno-Kustner B, Mayoral-Cleries F Neuropsychiatric disease and treatment 2021;17():1859-1868
Microglia activated by microbial neuraminidase contributes to ependymal cell death
Fernández-Arjona MDM, León-Rodríguez A, López-Ávalos MD, Grondona JM Fluids and barriers of the CNS 2021 Mar 23;18(1):15
Native alpha-Synuclein, 3-Nitrotyrosine Proteins, and Patterns of Nitro-alpha-Synuclein-Immunoreactive Inclusions in Saliva and Submandibulary Gland in Parkinson’s Disease
Fernández-Espejo E, Rodríguez de Fonseca F, Suárez J, Tolosa E, Vilas D, et al. Antioxidants (Basel, Switzerland) 2021 May 1;10(5):
Obesity as a Condition Determined by Food Addiction: Should Brain Endocannabinoid System Alterations Be the Cause and Its Modulation the Solution?
de Ceglia M, Decara J, Gaetani S, Rodríguez de Fonseca F Pharmaceuticals (Basel, Switzerland) 2021 Sep 29;14(10):
Palmitoleoylethanolamide Is an Efficient Anti-Obesity Endogenous Compound: Comparison with Oleylethanolamide in Diet-Induced Obesity
Tovar R, Gavito AL, Vargas A, Soverchia L, Hernandez-Folgado L, et al. Nutrients 2021 Jul 28;13(8):
Persistent changes in exploration and hyperactivity coexist with cognitive impairment in mice withdrawn from chronic cocaine
Mañas-Padilla MC, Ávila-Gámiz F, Gil-Rodríguez S, Ladrón de Guevara-Miranda D, Rodríguez de Fonseca F, et al. Physiology & behavior 2021 Oct 15;240():113542
Pigment epithelium-derived factor (PEDF) and PEDF-receptor in the adult mouse brain: Differential spatial/temporal localization pattern
de Diego-Otero, Y; Giraldez-Perez, RM; Lima-Cabello, E; Heredia-Farfan, R; Medina, RC; Sanchez-Salido, L; Costillas, LP JOURNAL OF COMPARATIVE NEUROLOGY 2021
Plasma concentrations of granulocyte colony-stimulating factor (G-CSF) in patients with substance use disorders and comorbid major depressive disorder
Galván ST, Flores-López M, Romero-Sanchiz P, Requena-Ocaña N, Porras-Perales O, et al. Scientific reports 2021 Jul 1;11(1):13629
Plasma Concentrations of Lysophosphatidic Acid and Autotaxin in Abstinent Patients with Alcohol Use Disorder and Comorbid Liver Disease
Flores-López M, García-Marchena N, Pavon FJ, Lara E, Porras-Perales O, et al. Biomedicines 2021 Sep 13;9(9):
Pregnancy-Associated Plasma Protein (PAPP)-A2 in Physiology and Disease
Barrios V, Chowen JA, Martín-Rivada Á, Guerra-Cantera S, Pozo J, et al. Cells 2021 Dec 18;10(12):
Recombinant IGF-1 Induces Sex-Specific Changes in Bone Composition and Remodeling in Adult Mice with Pappa2 Deficiency
Rubio L, Vargas A, Rivera P, López-Gambero AJ, Tovar R, et al. International journal of molecular sciences 2021 Apr 14;22(8):
Remote memory of drug experiences coexists with cognitive decline and abnormal adult neurogenesis in an animal model of cocaine-altered cognition
Manas-Padilla, MC; Gil-Rodriguez, S; Sampedro-Piquero, P; Avila-Gamiz, F; de Fonseca, FR; Santin, LJ; Castilla-Ortega, E ADDICTION BIOLOGY 2021
Selective inhibition of monoacylglycerol lipase is associated with passive coping behavior and attenuation of stress-induced dopamine release in the medial prefrontal cortex
Pavón FJ, Polis IY, Stouffer DG, Cravatt BF, Roberto M, et al. Neurobiology of stress 2021 May;14():100293
Sex-specific Associations of Alcohol Withdrawal in Patients Admitted for the Treatment of Alcohol Use Disorder
Sanvisens, A; Zuluaga, P; Short, A; Rubio, G; Gual, A; Torrens, M; Fuster, D; Bolao, F; de Fonseca, FR; Muga, R JOURNAL OF ADDICTION MEDICINE 2021
Sex-specific behavioral and neurogenic responses to cocaine in mice lacking and blocking dopamineD1or dopamineD2receptors
Rivera, P; Aranda, J; Alen, F; Vargas, A; Serrano, A; Pavon, FJ; Orio, L; Rubio, L; Moratalla, R; de Fonseca, FR; Suarez, J JOURNAL OF COMPARATIVE NEUROLOGY 2021
Sudden cessation of fluoxetine before alcohol drinking reinstatement alters microglial morphology and TLR4/inflammatory neuroadaptation in the rat brain
Aranda J, Fernández-Arjona MDM, Alén F, Rivera P, Rubio L, et al. Brain structure & function 2021 Sep;226(7):2243-2264
The Immune System through the Lens of Alcohol Intake and Gut Microbiota
Calleja-Conde J, Echeverry-Alzate V, Bühler KM, Durán-González P, Morales-García JÁ, et al. International journal of molecular sciences 2021 Jul 13;22(14):
A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA(1)), UCM-05194, Shows Efficacy in Neuropathic Pain Amelioration
González-Gil I, Zian D, Vázquez-Villa H, Hernández-Torres G, Martínez RF, et al. Journal of medicinal chemistry 2020 Mar 12;63(5):2372-2390
Abstinent patients with alcohol use disorders show an altered plasma cytokine profile: Identification of both interleukin 6 and interleukin 17A as potential biomarkers of consumption and comorbid liver and pancreatic diseases
García-Marchena N, Maza-Quiroga R, Serrano A, Barrios V, Requena-Ocaña N, et al. Journal of psychopharmacology (Oxford, England) 2020 Nov;34(11):1250-1260
Adult hippocampal neurogenesis as a target for cocaine addiction: a review of recent developments
Castilla-Ortega E, Santín LJ Current opinion in pharmacology 2020 Feb;50():109-116
Better data, better policy and better lives: a call for improved drug monitoring and concerted responses
Comiskey C, Bretteville-Jensen AL, Bergeron H, Bühringer G, Dargan P, et al. Addiction (Abingdon, England) 2020 Feb;115(2):199-200
Cessation of fluoxetine treatment increases alcohol seeking during relapse and dysregulates endocannabinoid and glutamatergic signaling in the central amygdala
Suárez J, Khom S, Alén F, Natividad LA, Varodayan FP, et al. Addiction biology 2020 Sep;25(5):e12813
Cocaine-induced changes in CX(3)CL1 and inflammatory signaling pathways in the hippocampus: Association with IL1 beta
Montesinos J, Castilla-Ortega E, Sánchez-Marín L, Montagud-Romero S, Araos P, et al. Neuropharmacology 2020 Jan 1;162():107840
COX-2 Inhibition Antagonizes Intra-Accumbens 2-Arachidonoylglycerol-Mediated Reduction in Ethanol Self-Administration in Rats
Pavon FJ, Polis I, Stouffer DG, Roberto M, Martin-Fardon R, et al. Alcoholism, clinical and experimental research 2020 Nov;44(11):2158-2165
D-Chiro-Inositol Treatment Affects Oocyte and Embryo Quality and Improves Glucose Intolerance in Both Aged Mice and Mouse Models of Polycystic Ovarian Syndrome
Pericuesta E, Laguna-Barraza R, Ramos-Ibeas P, Gutierrez-Arroyo JL, Navarro JA, et al. International journal of molecular sciences 2020 Aug 22;21(17):
Differential hepatoprotective role of the cannabinoid CB1 and CB2 receptors in paracetamol-induced liver injury
Rivera P, Vargas A, Pastor A, Boronat A, López-Gambero AJ, et al. British journal of pharmacology 2020 Jul;177(14):3309-3326
D-Pinitol fromCeratonia siliquaIs an Orally Active Natural Inositol That Reduces Pancreas Insulin Secretion and Increases Circulating Ghrelin Levels in Wistar Rats
Navarro JA, Decara J, Medina-Vera D, Tovar R, Suarez J, et al. Nutrients 2020 Jul 8;12(7):
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Imbalance of Endocannabinoid/Lysophosphatidylinositol Receptors Marks the Severity of Alzheimer’s Disease in a Preclinical Model: A Therapeutic Opportunity
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Inhibition of Receptor Protein Tyrosine Phosphatase beta/zeta Reduces Alcohol Intake in Rats
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Intermittent ethanol exposure during adolescence impairs cannabinoid type 1 receptor-dependent long-term depression and recognition memory in adult mice
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Lysophosphatidic Acid Receptor 1 Specifically Labels Seizure-Induced Hippocampal Reactive Neural Stem Cells and Regulates Their Division
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Peroxisome Proliferator-Activated Receptors: Experimental Targeting for the Treatment of Inflammatory Bowel Diseases
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Plasma tryptophan and kynurenine pathway metabolites in abstinent patients with alcohol use disorder and high prevalence of psychiatric comorbidity
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Potential association of plasma lysophosphatidic acid (LPA) species with cognitive impairment in abstinent alcohol use disorders outpatients
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Sex-Specific Anxiety and Prefrontal Cortex Glutamatergic Dysregulation Are Long-Term Consequences of Pre-and Postnatal Exposure to Hypercaloric Diet in a Rat Model
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Spectrophotometric Color Measurement to Assess Temperature of Exposure in Cortical and Medullar Heated Human Bones: A Preliminary Study
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Variation in chemokines plasma concentrations in primary care depressed patients associated with Internet-based cognitive-behavioral therapy
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A novel approach to childhood obesity: circulating chemokines and growth factors as biomarkers of insulin resistance
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Adipocyte cannabinoid CB1 receptor deficiency alleviates high fat diet-induced memory deficit, depressive-like behavior, neuroinflammation and impairment in adult neurogenesis
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Adult-onset hypothyroidism increases ethanol consumption
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Alcohol-induced cognitive deficits are associated with decreased circulating levels of the neurotrophin BDNF in humans and rats
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Brain Glucose-Sensing Mechanism and Energy Homeostasis
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Bupropion, a possible antidepressant without negative effects on alcohol relapse
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CB1 and LPA(1) Receptors Relationship in the Mouse Central Nervous System
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Cell Phone Use Habits Among the Spanish Population: Contribution of Applications to Problematic Use
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Central administration of galanin N-terminal fragment 1-15 decreases the voluntary alcohol intake in rats
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Defensive pessimism, optimism and adaptation to chronic pain
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Effects of the LPA(1) Receptor Deficiency and Stress on the Hippocampal LPA Species in Mice
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Ethanol-induced alterations in endocannabinoids and relevant neurotransmitters in the nucleus accumbens of fatty acid amide hydrolase knockout mice
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Highlighting the Role of Cognitive and Brain Reserve in the Substance use Disorder Field
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Inflammatory mediators and dual depression: Potential biomarkers in plasma of primary and substance-induced major depression in cocaine and alcohol use disorders
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Lysophosphatidic acid-induced increase in adult hippocampal neurogenesis facilitates the forgetting of cocaine-contextual memory
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Neuroplastic and cognitive impairment in substance use disorders: a therapeutic potential of cognitive stimulation
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Oleoylethanolamide Modulates BDNF-ERK Signaling and Neurogenesis in the Hippocampi of Rats Exposed to Delta(9)-THC and Ethanol Binge Drinking During Adolescence
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Oleoylethanolamide restores alcohol-induced inhibition of neuronal proliferation and microglial activity in striatum
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Oleoylethanolamide, Neuroinflammation, and Alcohol Abuse
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Perinatal free-choice of a high-calorie low-protein diet affects leptin signaling through IRS1 and AMPK dephosphorylation in the hypothalami of female rat offspring in adulthood
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Plasma concentrations of oleoylethanolamide in a primary care sample of depressed patients are increased in those treated with selective serotonin reuptake inhibitor-type antidepressants
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Serotonin is the main tryptophan metabolite associated with psychiatric comorbidity in abstinent cocaine-addicted patients
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Sex-Dimorphic Behavioral Alterations and Altered Neurogenesis in U12 Intron Splicing-Defective Zrsr1 Mutant Mice
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The presence of a social stimulus reduces cocaine-seeking in a place preference conditioning paradigm
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Cannabinoid dependence induces sustained changes in GABA release in the globus pallidus without affecting dopamine release in the dorsal striatum: A dual microdialysis probe study
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Cooperative role of the glucagon-like peptide-1 receptor and 3-adrenergic-mediated signalling on fat mass reduction through the downregulation of PKA/AKT/AMPK signalling in the adipose tissue and muscle of rats
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Deficient endocannabinoid signaling in the central amygdala contributes to alcohol dependence-related anxiety-like behavior and excessive alcohol intake
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Effects of genetic deletion versus pharmacological blockade of the LPA(1) receptor on depression-like behaviour and related brain functional activity
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Fatty acid amide hydrolase (FAAH) inactivation confers enhanced sensitivity to nicotine-induced dopamine release in the mouse nucleus accumbens
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Higher Impulsivity As a Distinctive Trait of Severe Cocaine Addiction among Individuals Treated for Cocaine or Alcohol Use Disorders
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Impaired Spermatogenesis, Muscle, and Erythrocyte Function in U12 Intron Splicing-Defective Zrsr1 Mutant Mice
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Inclusion of Alcoholic Associations Into a Public Treatment Programme for Alcoholism Improves Outcomes During the Treatment and Continuing Care Period: A 6-Year Experience
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Increased plasma oleoylethanolamide and palmitoleoylethanolamide levels correlate with inflammatory changes in alcohol binge drinkers: the case of HMGB1 in women
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Inflammatory gene expression in adipose tissue according to diagnosis of anxiety and mood disorders in obese and non-obese subjects
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Octadecylpropyl Sulfamide Reduces Neurodegeneration and Restores the Memory Deficits Induced by Hypoxia-Ischemia in Mice
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Palmitoylethanolamide attenuates cocaine-induced behavioral sensitization and conditioned place preference in mice
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Palmitoylethanolamide prevents neuroinflammation, reduces astrogliosis and preserves recognition and spatial memory following induction of neonatal anoxia-ischemia
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Patients with alcohol use disorder: initial results from a prospective multicenter registry in the Spanish Network on Addiction Disorders. CohRTA Study
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Pharmacological blockade of fatty acid amide hydrolase (FAAH) by URB597 improves memory and changes the phenotype of hippocampal microglia despite ethanol exposure
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PPAR alpha/CB1 receptor dual ligands as a novel therapy for alcohol use disorder: Evaluation of a novel oleic acid conjugate in preclinical rat models
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Red Bull (R) energy drink increases consumption of higher concentrations of alcohol
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Stress, Depression, Resilience and Ageing: A Role for the LPA-LPA(1) Pathway
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Systemic blockade of LPA(1/3) lysophosphatidic acid receptors by ki16425 modulates the effects of ethanol on the brain and behavior
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The adiponectin promoter activator NP-1 induces high levels of circulating TNF alpha and weight loss in obese (fa/fa) Zucker rats
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Training memory without aversion: Appetitive hole-board spatial learning increases adult hippocampal neurogenesis
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A moderate diet restriction during pregnancy alters the levels of endocannabinoids and endocannabinoid-related lipids in the hypothalamus, hippocampus and olfactory bulb of rat offspring in a sex-specific manner
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A Positive Allosteric Modulator of the Serotonin 5-HT2c Receptor for Obesity
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Acetaminophen-Induced Liver Injury Alters the Acyl Ethanolamine-Based Anti-Inflammatory Signaling System in Liver
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Acylethanolamides and endocannabinoid signaling system in dorsal striatum of rats exposed to perinatal asphyxia
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Decreased plasma concentrations of BDNF and IGF-1 in abstinent patients with alcohol use disorders
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Development of a Mobile Phone addiction craving scale and its Validation in a spanish adult Population
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Differences in the Rates of Drug Polyconsumption and Psychiatric Comorbidity among Patients with Cocaine Use Disorders According to the Mental Health Service
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Dopamine D-4 receptor stimulation prevents nigrostriatal dopamine pathway activation by morphine: relevance for drug addiction
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Effects of Intermittent Alcohol Exposure on Emotion and Cognition: A Potential Role for the Endogenous Cannabinoid System and Neuroinflammation
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Evaluation of plasma cytokines in patients with cocaine use disorders in abstinence identifies transforming growth factor alpha (TGF alpha) as a potential biomarker of consumption and dual diagnosis
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Glutamate and Brain Glutaminases in Drug Addiction
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Glutaminase and MMP-9 Downregulation in Cortex and Hippocampus of LPA(1) Receptor Null Mice Correlate with Altered Dendritic Spine Plasticity
Peñalver A, Campos-Sandoval JA, Blanco E, Cardona C, Castilla L, et al. Frontiers in molecular neuroscience 2017;10():278
Long-lasting memory deficits in mice withdrawn from cocaine are concomitant with neuroadaptations in hippocampal basal activity, GABAergic interneurons and adult neurogenesis
Ladrón de Guevara-Miranda D, Millón C, Rosell-Valle C, Pérez-Fernández M, Missiroli M, et al. Disease models & mechanisms 2017 Mar 1;10(3):323-336
Long-Term Effects of Intermittent Adolescent Alcohol Exposure in Male and Female Rats
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maLPA1-null mice as an endophenotype of anxious depression
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Neuronal Damage Induced by Perinatal Asphyxia Is Attenuated by Postinjury Glutaredoxin-2 Administration
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Oleoylethanolamide prevents neuroimmune HMGB1/TLR4/NF-kB danger signaling in rat frontal cortex and depressive-like behavior induced by ethanol binge administration
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Plasma Chemokines in Patients with Alcohol Use Disorders: Association of CCL11 (Eotaxin-1) with Psychiatric Comorbidity
García-Marchena N, Araos PF, Barrios V, Sánchez-Marín L, Chowen JA, et al. Frontiers in psychiatry 2016;7():214
Plasma concentrations of oleoylethanolamide and other acylethanolamides are altered in alcohol-dependent patients: effect of length of abstinence
Garcia-Marchena N, Pavon FJ, Pastor A, Araos P, Pedraz M, et al. Addiction biology 2017 Sep;22(5):1366-1377
Prevalence of problematic cell phone use in an adult population in Spain as assessed by the Mobile Phone Problem Use Scale (MPPUS)
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Psychiatric comorbidity and plasma levels of 2-acyl-glycerols in outpatient treatment alcohol users. Analysis of gender differences
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Psychological Factors and Alcohol Use in Problematic Mobile Phone Use in the Spanish Population
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Text mining and expert curation to develop a database on psychiatric diseases and their genes
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The CB1 receptor is required for the establishment of the hyperlocomotor phenotype in developmentally-induced hypothyroidism in mice
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The impact of cocaine on adult hippocampal neurogenesis: Potential neurobiological mechanisms and contributions to maladaptive cognition in cocaine addiction disorder
Castilla-Ortega E, Ladrón de Guevara-Miranda D, Serrano A, Pavón FJ, Suárez J, et al. Biochemical pharmacology 2017 Oct 1;141():100-117
The neuropeptides Galanin and Galanin(1-15) in depression-like behaviours
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A place for the hippocampus in the cocaine addiction circuit: Potential roles for adult hippocampal neurogenesis
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An Internet-Based Intervention for Depression in Primary Care in Spain: A Randomized Controlled Trial
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Antiobesity efficacy of GLP-1 receptor agonist liraglutide is associated with peripheral tissue-specific modulation of lipid metabolic regulators
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Both genetic deletion and pharmacological blockade of lysophosphatidic acid LPA(1) receptor results in increased alcohol consumption
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Can symptoms help in differential diagnosis between substance-induced vs independent psychosis in adults with a lifetime diagnosis of cocaine use disorder?
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Cannabinoid CB1 Receptors Are Localized in Striated Muscle Mitochondria and Regulate Mitochondrial Respiration
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Chronic IL-6 Administration Desensitizes IL-6 Response in Liver, Causes Hyperleptinemia and Aggravates Steatosis in Diet-Induced-Obese Mice
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Cocaine-conditioned place preference is predicted by previous anxiety-like behavior and is related to an increased number of neurons in the basolateral amygdala
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Cocaine-induced behavioral sensitization decreases the expression of endocannabinoid signaling-related proteins in the mouse hippocampus
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Effects of Adolescent Intermittent Alcohol Exposure on the Expression of Endocannabinoid Signaling-Related Proteins in the Spleen of Young Adult Rats
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ENVIRONMENTAL ENRICHMENT AS A THERAPEUTIC AVENUE FOR ANXIETY IN AGED WISTAR RATS: EFFECT ON CAT ODOR EXPOSITION AND GABAergic INTERNEURONS
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Environmental Enrichment, Age, and PPAR alpha Interact to Regulate Proliferation in Neurogenic Niches
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Exposure to a Highly Caloric Palatable Diet During Pregestational and Gestational Periods Affects Hypothalamic and Hippocampal Endocannabinoid Levels at Birth and Induces Adiposity and Anxiety-Like Behaviors in Male Rat Offspring
Ramírez-López MT, Vázquez M, Bindila L, Lomazzo E, Hofmann C, et al. Frontiers in behavioral neuroscience 2015;9():339
Exposure to a Highly Caloric Palatable Diet during the Perinatal Period Affects the Expression of the Endogenous Cannabinoid System in the Brain, Liver and Adipose Tissue of Adult Rat Offspring
Ramírez-López MT, Arco R, Decara J, Vázquez M, Noemí Blanco R, et al. PloS one 2016;11(11):e0165432
Long-Term Effects of Prenatal Exposure to Undernutrition on Cannabinoid Receptor-Related Behaviors: Sex and Tissue-Specific Alterations in the mRNA Expression of Cannabinoid Receptors and Lipid Metabolic Regulators
Ramírez-López MT, Arco R, Decara J, Vázquez M, Rivera P, et al. Frontiers in behavioral neuroscience 2016;10():241
Maternal Caloric Restriction Implemented during the Preconceptional and Pregnancy Period Alters Hypothalamic and Hippocampal Endocannabinoid Levels at Birth and Induces Overweight and Increased Adiposity at Adulthood in Male Rat Offspring
Ramírez-López MT, Vázquez M, Bindila L, Lomazzo E, Hofmann C, et al. Frontiers in behavioral neuroscience 2016;10():208
Nalmefene is effective at reducing alcohol seeking, treating alcohol-cocaine interactions and reducing alcohol-induced histone deacetylases gene expression in blood
Calleja-Conde J, Echeverry-Alzate V, Giné E, Bühler KM, Nadal R, et al. British journal of pharmacology 2016 Aug;173(16):2490-505
Pharmacological reduction of adult hippocampal neurogenesis modifies functional brain circuits in mice exposed to a cocaine conditioned place preference paradigm
Castilla-Ortega E, Blanco E, Serrano A, Ladrón de Guevara-Miranda D, Pedraz M, et al. Addiction biology 2016 May;21(3):575-88
Role of the satiety factor oleoylethanolamide in alcoholism
Bilbao A, Serrano A, Cippitelli A, Pavón FJ, Giuffrida A, et al. Addiction biology 2016 Jul;21(4):859-72
Single administration of recombinant IL-6 restores the gene expression of lipogenic enzymes in liver of fasting IL-6-deficient mice
Gavito AL, Cabello R, Suarez J, Serrano A, Pavón FJ, et al. British journal of pharmacology 2016 Mar;173(6):1070-84
Spinal cord compression injury in lysophosphatidic acid 1 receptor-null mice promotes maladaptive pronociceptive descending control.
Suardíaz M, Galan-Arriero I, Avila-Martin G, Estivill-Torrús G, de Fonseca FR, et al. European journal of pain (London, England) 2016 Feb;20(2):176-85
Activation of Lysophosphatidic Acid Receptor Type 1 Contributes to Pathophysiology of Spinal Cord Injury
Santos-Nogueira E, López-Serrano C, Hernández J, Lago N, Astudillo AM, et al. The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 Jul 15;35(28):10224-35
Anatomical location of LPA(1) activation and LPA phospholipid precursors in rodent and human brain
González de San Román E, Manuel I, Giralt MT, Chun J, Estivill-Torrús G, et al. Journal of neurochemistry 2015 Aug;134(3):471-85
Chronic administration of recombinant IL-6 upregulates lipogenic enzyme expression and aggravates high-fat-diet-induced steatosis in IL-6-deficient mice
Vida M, Gavito AL, Pavón FJ, Bautista D, Serrano A, et al. Disease models & mechanisms 2015 Jul 1;8(7):721-31
Cocaine-Induced Behavioral Sensitization Is Associated With Changes in the Expression of Endocannabinoid and Glutamatergic Signaling Systems in the Mouse Prefrontal Cortex
Blanco E, Pavón FJ, Palomino A, Luque-Rojas MJ, Serrano A, et al. The international journal of neuropsychopharmacology 2014 Oct 31;18(1):
Common single nucleotide variants underlying drug addiction: more than a decade of research
Bühler KM, Giné E, Echeverry-Alzate V, Calleja-Conde J, de Fonseca FR, et al. Addiction biology 2015 Sep;20(5):845-71
Effects of Synchronous and Asynchronous Embryo Transfer on Postnatal Development, Adult Health, and Behavior in Mice
López-Cardona AP, Fernández-González R, Pérez-Crespo M, Alén F, de Fonseca FR, et al. Biology of reproduction 2015 Oct;93(4):85
Expectations Among Patients and Health Professionals Regarding Web-Based Interventions for Depression in Primary Care: A Qualitative Study
Montero-Marín J, Prado-Abril J, Botella C, Mayoral-Cleries F, Baños R, et al. Journal of medical Internet research 2015 Mar 10;17(3):e67
Histone Deacetylase Gene Expression Following Binge Alcohol Consumption in Rats and Humans
López-Moreno JA, Marcos M, Calleja-Conde J, Echeverry-Alzate V, Bühler KM, et al. Alcoholism, clinical and experimental research 2015 Oct;39(10):1939-50
Life-long environmental enrichment counteracts spatial learning, reference and working memory deficits in middle-aged rats subjected to perinatal asphyxia
Galeano P, Blanco E, Logica Tornatore TM, Romero JI, Holubiec MI, et al. Frontiers in behavioral neuroscience 2014;8():406
Loss of lysophosphatidic acid receptor LPA(1) alters oligodendrocyte differentiation and myelination in the mouse cerebral cortex
García-Díaz B, Riquelme R, Varela-Nieto I, Jiménez AJ, de Diego I, et al. Brain structure & function 2015 Nov;220(6):3701-20
Narrow Specificity of Responsibility and Intolerance of Uncertainty in Obsessive-Compulsive Behavior and Generalized Anxiety Symptoms
Romero-Sanchiz, P; Nogueira-Arjona, R; Godoy-Avila, A; Gavino-Lazaro, A; Freeston, MH INTERNATIONAL JOURNAL OF COGNITIVE THERAPY 2015
Novel Oxazolidinone-Based Peroxisome Proliferator Activated Receptor Agonists: Molecular Modeling, Synthesis, and Biological Evaluation
Fresno N, Macías-González M, Torres-Zaguirre A, Romero-Cuevas M, Sanz-Camacho P, et al. Journal of medicinal chemistry 2015 Aug 27;58(16):6639-52
Perinatal asphyxia results in altered expression of the hippocampal acylethanolamide/endocannabinoid signaling system associated to memory impairments in postweaned rats
Blanco E, Galeano P, Holubiec MI, Romero JI, Logica T, et al. Frontiers in neuroanatomy 2015;9():141
Pharmacological activation of CB2 receptors counteracts the deleterious effect of ethanol on cell proliferation in the main neurogenic zones of the adult rat brain
Rivera P, Blanco E, Bindila L, Alen F, Vargas A, et al. Frontiers in cellular neuroscience 2015;9():379
Pharmacological Blockade of Cannabinoid CB1 Receptors in Diet-Induced Obesity Regulates Mitochondrial Dihydrolipoamide Dehydrogenase in Muscle
Arrabal S, Lucena MA, Canduela MJ, Ramos-Uriarte A, Rivera P, et al. PloS one 2015;10(12):e0145244
Pharmacological blockade of the fatty acid amide hydrolase (FAAH) alters neural proliferation, apoptosis and gliosis in the rat hippocampus, hypothalamus and striatum in a negative energy context
Rivera P, Bindila L, Pastor A, Pérez-Martín M, Pavón FJ, et al. Frontiers in cellular neuroscience 2015;9():98
Plasma Concentrations of BDNF and IGF-1 in Abstinent Cocaine Users with High Prevalence of Substance Use Disorders: Relationship to Psychiatric Comorbidity
Pedraz M, Martín-Velasco AI, García-Marchena N, Araos P, Serrano A, et al. PloS one 2015;10(3):e0118610
Plasma profile of pro-inflammatory cytokines and chemokines in cocaine users under outpatient treatment: influence of cocaine symptom severity and psychiatric co-morbidity
Araos P, Pedraz M, Serrano A, Lucena M, Barrios V, et al. Addiction biology 2015 Jul;20(4):756-72
Spectrophotometric analysis of color changes in teeth incinerated at increasing temperatures
Rubio L, Sioli JM, Suarez J, Gaitan MJ, Martin-de-las-Heras S Forensic science international 2015 Jul;252():193.e1-6
Systemic Administration of Oleoylethanolamide Protects from Neuroinflammation and Anhedonia Induced by LPS in Rats
Sayd A, Antón M, Alén F, Caso JR, Pavón J, et al. The international journal of neuropsychopharmacology 2014 Dec 28;18(6):
THE ROLE OF MATERNAL DIET IN METABOLIC AND BEHAVIOURAL PROGRAMMING: REVIEW OF BIOLOGIC MECHANISMS INVOLVED
Ramírez-López MT, Vázquez Berrios M, Arco González R, Blanco Velilla RN, Decara Del Olmo J, et al. Nutricion hospitalaria 2015 Dec 1;32(6):2433-45
Treatment with a novel oleic-acid-dihydroxyamphetamine conjugation ameliorates non-alcoholic fatty liver disease in obese Zucker rats
Decara JM, Pavón FJ, Suárez J, Romero-Cuevas M, Baixeras E, et al. Disease models & mechanisms 2015 Oct 1;8(10):1213-25
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