Tissue Bioengineering and Regeneration Laboratory (LABRET) (IBIMA TECH)(IBIMA RARE)

Lineas de Investigación

01. Tissue regeneration. Skeletal tissue engineering. Therapeutic osteogenesis and chondrogenesis.

02. Design and production of biomolecules and biomaterials for regenerative medicine of the musculoskeletal system.

03. Cell therapy based on mesenchymal stem cells (MSCs).

04. Production and characterisation of the MSC secrotome. Therapeutic possibilities in inflammatory and immunomediated pathologies.



Proyectos de Investigación

Mesenchymal stem cell secretome delivery system based on a microparticulate hybrid dressing for chronic skin wound healing (MICRO-SEC)

ISCIII
. 2019

Secretoma de Células Madre Mesenquimales de Tejido Adiposo Canino (cAD-MSCs) y Desarrollo de su Aplicación Clínica en Medicina Veterinaria (SecMeV)

Junta de Andalucía
. 2019

Alterntive therapies for low bone density diseases through modulation of the celular stress

Junta de Andalucía
. 2019

PI-0332-2016 Implantes Personalizados de Titanio Poroso para Defectos Maxilares Segmentarios: Mejora de la Osteointegración y Reparación Tisular Mediante Ingeniería de Tejidos

CONSEJERÍA DE SALUD
PROYECTOS DE INVESTIGACIÓN EN SALUD 2016

RD16/0011/0022 Red de Terapia Celular – TerCel

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONVOCATORIA DE REDES TEMÁTICAS DE INVESTIGACIÓN COOPERATIVA EN SALUD (RETICS) 2016

Publicaciones científicas

  • Todo
  • D1
  • Q1
  • Q2
  • Otro

Copper-containing mesoporous bioactive glass promotes angiogenesis in an in vivo zebrafish model

Romero-Sanchez, LB; Mari-Beffa, M; Carrillo, P; Medina, MA; Diaz-Cuenca, A
Acta Biomaterialia 2018


Safety and efficacy of the mesenchymal stem cell in feline eosinophilic keratitis treatment

Villatoro, AJ; Claros, S; Fernandez, V; Alcoholado, C; Farinas, F; Moreno, A; Becerra, J; Andrades, JA
Bmc Veterinary Research 2018


Fishing anti(lymph)angiogenic drugs with zebrafish

Garcia-Caballero, M; Quesada, AR; Medina, MA; Mari-Beffa, M
Drug Discovery Today 2018


Widening control of fin inter-rays in zebrafish and inferences about actinopterygian fins

Murciano, C; Cazorla-Vazquez, S; Gutierrez, J; Hijano, JA; Ruiz-Sanchez, J; Mesa-Almagro, L; Martin-Reyes, F; Fernandez, TD; Mari-Beffa, M
Journal Of Anatomy 2018


Repair of maxillary cystic bone defects with mesenchymal stem cells seeded on a cross-linked serum scaffold

Redondo, LM; Garcia, V; Peral, B; Verrier, A; Becerra, J; Sanchez, A; Garcia-Sancho, J
Journal Of Cranio-Maxillofacial Surgery 2018


Dendrimer-based Uneven Nanopatterns to Locally Control Surface Adhesiveness: A Method to Direct Chondrogenic Differentiation

Casanellas, I; Lagunas, A; Tsintzou, I; Vida, Y; Collado, D; Perez-Inestrosa, E; Rodriguez-Pereira, C; Magalhaes, J; Gorostiza, P; Andrades, JA; Becerra, J; Samitier, J
Jove-Journal Of Visualized Experiments 2018


Brain Glucose-Sensing Mechanism and Energy Homeostasis.

Lopez-Gambero, A J; Martinez, F; Salazar, K; Cifuentes, M; Nualart, F
Molecular Neurobiology 2018


Expression of a Novel Ciliary Protein, IIIG9, During the Differentiation and Maturation of Ependymal Cells

Cifuentes, M; Baeza, V; Arrabal, PM; Visser, R; Grondona, JM; Saldivia, N; Martinez, F; Nualart, F; Salazar, K
Molecular Neurobiology 2018


SVCT2 Expression and Function in Reactive Astrocytes Is a Common Event in Different Brain Pathologies

Salazar, K; Martinez, F; Perez-Martin, M; Cifuentes, M; Trigueros, L; Ferrada, L; Espinoza, F; Saldivia, N; Bertinat, R; Forman, K; Oviedo, MJ; Lopez-Gambero, AJ; Bonansco, C; Bongarzone, ER; Nualart, F
Molecular Neurobiology 2018


Glioblastoma Bystander Cell Therapy: Improvements in Treatment and Insights into the Therapy Mechanisms

Guerra-Rebollo, M; de Moraes, CN; Alcoholado, C; Soler-Botija, C; Sanchez-Cid, L; Vila, OF; Meca-Cortes, O; Ramos-Romero, S; Rubio, N; Becerra, J; Blanco, J; Garrido, C
Molecular Therapy-Oncolytics 2018


Allogeneic adipose-derived mesenchymal stem cell therapy in dogs with refractory atopic dermatitis: clinical efficacy and safety

Villatoro, AJ; Hermida-Prieto, M; Fernandez, V; Farinas, F; Alcoholado, C; Rodriguez-Garcia, MI; Marinas-Pardo, L; Becerra, J
Veterinary Record 2018

Aging Selectively Modulates Vitamin C Transporter Expression Patterns in the Kidney

Forman, K; Martinez, F; Cifuentes, M; Bertinat, R; Salazar, K; Nualart, FJournal Of Cellular Physiology. 2017

Regenerative Endodontic Procedures: A Perspective from Stem Cell Niche Biology

Mari-Beffa, M; Segura-Egea, JJ; Diaz-Cuenca, AJournal Of Endodontics. 2017

Tailoring RGD local surface density at the nanoscale toward adult stem cell chondrogenic commitment

Lagunas, A; Tsintzou, I; Vida, Y; Collado, D; Perez-Inestrosa, E; Pereira, CR; Magalhaes, J; Andrades, JA; Samitier, JNano Research. 2017

Floating hip and associated injuries

Zamora-Navas, P; Estades-Rubio, FJ; Cano, JR; Guerado, EInjury-International Journal Of The Care Of The Injured. 2017

Microbial neuraminidase induces a Moderate and Transient Myelin Vacuolation independent of complement system activation

Granados-Duran, P; Lopez-Avalos, MD; Cifuentes, M; Perez-Martin, M; Fernandez-Arjona, MD; Hughes, TR; Johnson, K; Morgan, BP; Fernandez-Llebrez, P; Grondona, JMFrontiers In Neurology. 2017

Regenerative Therapies in Dry Eye Disease: From Growth Factors to Cell Therapy

Villatoro, AJ; Fernandez, V; Claros, S; Alcoholado, C; Cifuentes, M; Merayo-Lloves, J; Andrades, JA; Becerra, JInternational Journal Of Molecular Sciences. 2017


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